143 related articles for article (PubMed ID: 31663737)
1. Discovery of Small Molecule Antagonists of the USP5 Zinc Finger Ubiquitin-Binding Domain.
Mann MK; Franzoni I; de Freitas RF; Tempel W; Houliston S; Smith L; Vedadi M; Arrowsmith CH; Harding RJ; Schapira M
J Med Chem; 2019 Nov; 62(22):10144-10155. PubMed ID: 31663737
[TBL] [Abstract][Full Text] [Related]
2. Structure-Activity Relationship of USP5 Inhibitors.
Mann MK; Zepeda-Velázquez CA; González-Álvarez H; Dong A; Kiyota T; Aman AM; Loppnau P; Li Y; Wilson B; Arrowsmith CH; Al-Awar R; Harding RJ; Schapira M
J Med Chem; 2021 Oct; 64(20):15017-15036. PubMed ID: 34648286
[TBL] [Abstract][Full Text] [Related]
3. Two ZnF-UBP domains in isopeptidase T (USP5).
Avvakumov GV; Walker JR; Xue S; Allali-Hassani A; Asinas A; Nair UB; Fang X; Zuo X; Wang YX; Wilkinson KD; Dhe-Paganon S
Biochemistry; 2012 Feb; 51(6):1188-98. PubMed ID: 22283393
[TBL] [Abstract][Full Text] [Related]
4. Structure-based virtual screening of novel USP5 inhibitors targeting the zinc finger ubiquitin-binding domain.
Wang T; Tong J; Zhang X; Wang Z; Xu L; Pan P; Hou T
Comput Biol Med; 2024 May; 174():108397. PubMed ID: 38603896
[TBL] [Abstract][Full Text] [Related]
5. Molecular dynamics of zinc-finger ubiquitin binding domains: a comparative study of histone deacetylase 6 and ubiquitin-specific protease 5.
Dos Santos Passos C; Simões-Pires CA; Carrupt PA; Nurisso A
J Biomol Struct Dyn; 2016 Dec; 34(12):2581-2598. PubMed ID: 26619262
[TBL] [Abstract][Full Text] [Related]
6. Identification and Structure-Activity Relationship of HDAC6 Zinc-Finger Ubiquitin Binding Domain Inhibitors.
Ferreira de Freitas R; Harding RJ; Franzoni I; Ravichandran M; Mann MK; Ouyang H; Lautens M; Santhakumar V; Arrowsmith CH; Schapira M
J Med Chem; 2018 May; 61(10):4517-4527. PubMed ID: 29741882
[TBL] [Abstract][Full Text] [Related]
7. Recognition of polyubiquitin isoforms by the multiple ubiquitin binding modules of isopeptidase T.
Reyes-Turcu FE; Shanks JR; Komander D; Wilkinson KD
J Biol Chem; 2008 Jul; 283(28):19581-92. PubMed ID: 18482987
[TBL] [Abstract][Full Text] [Related]
8. Structural insights into interactions between ubiquitin specific protease 5 and its polyubiquitin substrates by mass spectrometry and ion mobility spectrometry.
Scott D; Layfield R; Oldham NJ
Protein Sci; 2015 Aug; 24(8):1257-63. PubMed ID: 25970461
[TBL] [Abstract][Full Text] [Related]
9. Structure and function of USP5: Insight into physiological and pathophysiological roles.
Ning F; Xin H; Liu J; Lv C; Xu X; Wang M; Wang Y; Zhang W; Zhang X
Pharmacol Res; 2020 Jul; 157():104557. PubMed ID: 31756387
[TBL] [Abstract][Full Text] [Related]
10. Structural and functional studies of USP20 ZnF-UBP domain by NMR.
Yang Y; Ding Y; Zhou C; Wen Y; Zhang N
Protein Sci; 2019 Sep; 28(9):1606-1619. PubMed ID: 31278784
[TBL] [Abstract][Full Text] [Related]
11. The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin.
Reyes-Turcu FE; Horton JR; Mullally JE; Heroux A; Cheng X; Wilkinson KD
Cell; 2006 Mar; 124(6):1197-208. PubMed ID: 16564012
[TBL] [Abstract][Full Text] [Related]
12. Method for the Purification of Endogenous Unanchored Polyubiquitin Chains.
Scott D; Strachan J; Krishna VG; Shaw B; Tooth DJ; Searle MS; Oldham NJ; Layfield R
Methods Mol Biol; 2016; 1449():203-13. PubMed ID: 27613037
[TBL] [Abstract][Full Text] [Related]
13. Small Molecule Antagonists of the Interaction between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin.
Harding RJ; Ferreira de Freitas R; Collins P; Franzoni I; Ravichandran M; Ouyang H; Juarez-Ornelas KA; Lautens M; Schapira M; von Delft F; Santhakumar V; Arrowsmith CH
J Med Chem; 2017 Nov; 60(21):9090-9096. PubMed ID: 29019676
[TBL] [Abstract][Full Text] [Related]
14. Zinc-finger UBPs: regulators of deubiquitylation.
Bonnet J; Romier C; Tora L; Devys D
Trends Biochem Sci; 2008 Aug; 33(8):369-75. PubMed ID: 18603431
[TBL] [Abstract][Full Text] [Related]
15. Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6.
Harding RJ; Franzoni I; Mann MK; Szewczyk MM; Mirabi B; Ferreira de Freitas R; Owens DDG; Ackloo S; Scheremetjew A; Juarez-Ornelas KA; Sanichar R; Baker RJ; Dank C; Brown PJ; Barsyte-Lovejoy D; Santhakumar V; Schapira M; Lautens M; Arrowsmith CH
J Med Chem; 2023 Aug; 66(15):10273-10288. PubMed ID: 37499118
[TBL] [Abstract][Full Text] [Related]
16. Domain analysis reveals that a deubiquitinating enzyme USP13 performs non-activating catalysis for Lys63-linked polyubiquitin.
Zhang YH; Zhou CJ; Zhou ZR; Song AX; Hu HY
PLoS One; 2011; 6(12):e29362. PubMed ID: 22216260
[TBL] [Abstract][Full Text] [Related]
17. Vialinin A is a ubiquitin-specific peptidase inhibitor.
Okada K; Ye YQ; Taniguchi K; Yoshida A; Akiyama T; Yoshioka Y; Onose J; Koshino H; Takahashi S; Yajima A; Abe N; Yajima S
Bioorg Med Chem Lett; 2013 Aug; 23(15):4328-31. PubMed ID: 23791076
[TBL] [Abstract][Full Text] [Related]
18. USP5 Is Dispensable for Monoubiquitin Maintenance in Drosophila.
Ristic G; Tsou WL; Guzi E; Kanack AJ; Scaglione KM; Todi SV
J Biol Chem; 2016 Apr; 291(17):9161-72. PubMed ID: 26917723
[TBL] [Abstract][Full Text] [Related]
19. Sulfamide as Zinc Binding Motif in Small Molecule Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa).
Halland N; Czech J; Czechtizky W; Evers A; Follmann M; Kohlmann M; Schreuder HA; Kallus C
J Med Chem; 2016 Oct; 59(20):9567-9573. PubMed ID: 27749053
[TBL] [Abstract][Full Text] [Related]
20. Identification of covalent active site inhibitors of dengue virus protease.
Koh-Stenta X; Joy J; Wang SF; Kwek PZ; Wee JL; Wan KF; Gayen S; Chen AS; Kang C; Lee MA; Poulsen A; Vasudevan SG; Hill J; Nacro K
Drug Des Devel Ther; 2015; 9():6389-99. PubMed ID: 26677315
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
