These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 31665086)

  • 1. Neuropathology of RAN translation proteins in fragile X-associated tremor/ataxia syndrome.
    Krans A; Skariah G; Zhang Y; Bayly B; Todd PK
    Acta Neuropathol Commun; 2019 Oct; 7(1):152. PubMed ID: 31665086
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Composition of the Intranuclear Inclusions of Fragile X-associated Tremor/Ataxia Syndrome.
    Ma L; Herren AW; Espinal G; Randol J; McLaughlin B; Martinez-Cerdeño V; Pessah IN; Hagerman RJ; Hagerman PJ
    Acta Neuropathol Commun; 2019 Sep; 7(1):143. PubMed ID: 31481131
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Repeat-associated non-AUG translation from antisense CCG repeats in fragile X tremor/ataxia syndrome.
    Krans A; Kearse MG; Todd PK
    Ann Neurol; 2016 Dec; 80(6):871-881. PubMed ID: 27761921
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Astroglial-targeted expression of the fragile X CGG repeat premutation in mice yields RAN translation, motor deficits and possible evidence for cell-to-cell propagation of FXTAS pathology.
    Wenzel HJ; Murray KD; Haify SN; Hunsaker MR; Schwartzer JJ; Kim K; La Spada AR; Sopher BL; Hagerman PJ; Raske C; Severijnen LWFM; Willemsen R; Hukema RK; Berman RF
    Acta Neuropathol Commun; 2019 Feb; 7(1):27. PubMed ID: 30808398
    [TBL] [Abstract][Full Text] [Related]  

  • 5. CGG repeat-associated translation mediates neurodegeneration in fragile X tremor ataxia syndrome.
    Todd PK; Oh SY; Krans A; He F; Sellier C; Frazer M; Renoux AJ; Chen KC; Scaglione KM; Basrur V; Elenitoba-Johnson K; Vonsattel JP; Louis ED; Sutton MA; Taylor JP; Mills RE; Charlet-Berguerand N; Paulson HL
    Neuron; 2013 May; 78(3):440-55. PubMed ID: 23602499
    [TBL] [Abstract][Full Text] [Related]  

  • 6. FMRpolyG alters mitochondrial transcripts level and respiratory chain complex assembly in Fragile X associated tremor/ataxia syndrome [FXTAS].
    Gohel D; Sripada L; Prajapati P; Singh K; Roy M; Kotadia D; Tassone F; Charlet-Berguerand N; Singh R
    Biochim Biophys Acta Mol Basis Dis; 2019 Jun; 1865(6):1379-1388. PubMed ID: 30771487
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Presence of inclusions positive for polyglycine containing protein, FMRpolyG, indicates that repeat-associated non-AUG translation plays a role in fragile X-associated primary ovarian insufficiency.
    Buijsen RA; Visser JA; Kramer P; Severijnen EA; Gearing M; Charlet-Berguerand N; Sherman SL; Berman RF; Willemsen R; Hukema RK
    Hum Reprod; 2016 Jan; 31(1):158-68. PubMed ID: 26537920
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RAN translation at CGG repeats induces ubiquitin proteasome system impairment in models of fragile X-associated tremor ataxia syndrome.
    Oh SY; He F; Krans A; Frazer M; Taylor JP; Paulson HL; Todd PK
    Hum Mol Genet; 2015 Aug; 24(15):4317-26. PubMed ID: 25954027
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome.
    Sellier C; Buijsen RAM; He F; Natla S; Jung L; Tropel P; Gaucherot A; Jacobs H; Meziane H; Vincent A; Champy MF; Sorg T; Pavlovic G; Wattenhofer-Donze M; Birling MC; Oulad-Abdelghani M; Eberling P; Ruffenach F; Joint M; Anheim M; Martinez-Cerdeno V; Tassone F; Willemsen R; Hukema RK; Viville S; Martinat C; Todd PK; Charlet-Berguerand N
    Neuron; 2017 Jan; 93(2):331-347. PubMed ID: 28065649
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FMRpolyG accumulates in FMR1 premutation granulosa cells.
    Friedman-Gohas M; Elizur SE; Dratviman-Storobinsky O; Aizer A; Haas J; Raanani H; Orvieto R; Cohen Y
    J Ovarian Res; 2020 Feb; 13(1):22. PubMed ID: 32101156
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Neuropathology of fragile X-associated tremor/ataxia syndrome (FXTAS).
    Greco CM; Berman RF; Martin RM; Tassone F; Schwartz PH; Chang A; Trapp BD; Iwahashi C; Brunberg J; Grigsby J; Hessl D; Becker EJ; Papazian J; Leehey MA; Hagerman RJ; Hagerman PJ
    Brain; 2006 Jan; 129(Pt 1):243-55. PubMed ID: 16332642
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular Pathophysiology of Fragile X-Associated Tremor/Ataxia Syndrome and Perspectives for Drug Development.
    Botta-Orfila T; Tartaglia GG; Michalon A
    Cerebellum; 2016 Oct; 15(5):599-610. PubMed ID: 27277287
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Between Order and Chaos: Understanding the Mechanism and Pathology of RAN Translation.
    Reyes CJF; Asano K
    Biol Pharm Bull; 2023; 46(2):139-146. PubMed ID: 36724941
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Potential pathogenic mechanisms underlying Fragile X Tremor Ataxia Syndrome: RAN translation and/or RNA gain-of-function?
    Boivin M; Willemsen R; Hukema RK; Sellier C
    Eur J Med Genet; 2018 Nov; 61(11):674-679. PubMed ID: 29223504
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CGG repeat RNA G-quadruplexes interact with FMRpolyG to cause neuronal dysfunction in fragile X-related tremor/ataxia syndrome.
    Asamitsu S; Yabuki Y; Ikenoshita S; Kawakubo K; Kawasaki M; Usuki S; Nakayama Y; Adachi K; Kugoh H; Ishii K; Matsuura T; Nanba E; Sugiyama H; Fukunaga K; Shioda N
    Sci Adv; 2021 Jan; 7(3):. PubMed ID: 33523882
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ubiquitin-positive intranuclear inclusions in neuronal and glial cells in a mouse model of the fragile X premutation.
    Wenzel HJ; Hunsaker MR; Greco CM; Willemsen R; Berman RF
    Brain Res; 2010 Mar; 1318():155-66. PubMed ID: 20051238
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fragile X-associated tremor ataxia syndrome with co-occurrent progressive supranuclear palsy-like neuropathology.
    Sacino AN; Prokop S; Walsh MA; Adamson J; Subramony SH; Krans A; Todd PK; Giasson BI; Yachnis AT
    Acta Neuropathol Commun; 2019 Oct; 7(1):158. PubMed ID: 31665069
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Small molecule 1a reduces FMRpolyG-mediated toxicity in in vitro and in vivo models for FMR1 premutation.
    Haify SN; Buijsen RAM; Verwegen L; Severijnen LWFM; de Boer H; Boumeester V; Monshouwer R; Yang WY; Cameron MD; Willemsen R; Disney MD; Hukema RK
    Hum Mol Genet; 2021 Aug; 30(17):1632-1648. PubMed ID: 34077515
    [TBL] [Abstract][Full Text] [Related]  

  • 19. FMRpolyG-positive inclusions in CNS and non-CNS organs of a fragile X premutation carrier with fragile X-associated tremor/ataxia syndrome.
    Buijsen RA; Sellier C; Severijnen LA; Oulad-Abdelghani M; Verhagen RF; Berman RF; Charlet-Berguerand N; Willemsen R; Hukema RK
    Acta Neuropathol Commun; 2014 Nov; 2():162. PubMed ID: 25471011
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lack of a Clear Behavioral Phenotype in an Inducible FXTAS Mouse Model Despite the Presence of Neuronal FMRpolyG-Positive Aggregates.
    Haify SN; Mankoe RSD; Boumeester V; van der Toorn EC; Verhagen RFM; Willemsen R; Hukema RK; Bosman LWJ
    Front Mol Biosci; 2020; 7():599101. PubMed ID: 33381520
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.