BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

254 related articles for article (PubMed ID: 31665549)

  • 1. Regulation of the MDM2-p53 pathway by the ubiquitin ligase HERC2.
    García-Cano J; Sánchez-Tena S; Sala-Gaston J; Figueras A; Viñals F; Bartrons R; Ventura F; Rosa JL
    Mol Oncol; 2020 Jan; 14(1):69-86. PubMed ID: 31665549
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The E3 ubiquitin protein ligase HERC2 modulates the activity of tumor protein p53 by regulating its oligomerization.
    Cubillos-Rojas M; Amair-Pinedo F; Peiró-Jordán R; Bartrons R; Ventura F; Rosa JL
    J Biol Chem; 2014 May; 289(21):14782-95. PubMed ID: 24722987
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of Mdm2 protein stability and the p53 response by NEDD4-1 E3 ligase.
    Xu C; Fan CD; Wang X
    Oncogene; 2015 Jan; 34(3):281-9. PubMed ID: 24413081
    [TBL] [Abstract][Full Text] [Related]  

  • 4. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage.
    Fu X; Yucer N; Liu S; Li M; Yi P; Mu JJ; Yang T; Chu J; Jung SY; O'Malley BW; Gu W; Qin J; Wang Y
    Proc Natl Acad Sci U S A; 2010 Mar; 107(10):4579-84. PubMed ID: 20173098
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of the Mdm2-p53 pathway by the ubiquitin E3 ligase MARCH7.
    Zhao K; Yang Y; Zhang G; Wang C; Wang D; Wu M; Mei Y
    EMBO Rep; 2018 Feb; 19(2):305-319. PubMed ID: 29295817
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TRIAD1 inhibits MDM2-mediated p53 ubiquitination and degradation.
    Bae S; Jung JH; Kim K; An IS; Kim SY; Lee JH; Park IC; Jin YW; Lee SJ; An S
    FEBS Lett; 2012 Sep; 586(19):3057-63. PubMed ID: 22819825
    [TBL] [Abstract][Full Text] [Related]  

  • 7. UBTD1 induces cellular senescence through an UBTD1-Mdm2/p53 positive feedback loop.
    Zhang XW; Wang XF; Ni SJ; Qin W; Zhao LQ; Hua RX; Lu YW; Li J; Dimri GP; Guo WJ
    J Pathol; 2015 Mar; 235(4):656-67. PubMed ID: 25382750
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of MDM2 E3 ligase activity by phosphorylation after DNA damage.
    Cheng Q; Cross B; Li B; Chen L; Li Z; Chen J
    Mol Cell Biol; 2011 Dec; 31(24):4951-63. PubMed ID: 21986495
    [TBL] [Abstract][Full Text] [Related]  

  • 9. FKBP25, a novel regulator of the p53 pathway, induces the degradation of MDM2 and activation of p53.
    Ochocka AM; Kampanis P; Nicol S; Allende-Vega N; Cox M; Marcar L; Milne D; Fuller-Pace F; Meek D
    FEBS Lett; 2009 Feb; 583(4):621-6. PubMed ID: 19166840
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cisplatin causes cell death via TAB1 regulation of p53/MDM2/MDMX circuitry.
    Zhu Y; Regunath K; Jacq X; Prives C
    Genes Dev; 2013 Aug; 27(16):1739-51. PubMed ID: 23934659
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ATM activates p53 by regulating MDM2 oligomerization and E3 processivity.
    Cheng Q; Chen L; Li Z; Lane WS; Chen J
    EMBO J; 2009 Dec; 28(24):3857-67. PubMed ID: 19816404
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential response between the p53 ubiquitin-protein ligases Pirh2 and MdM2 following DNA damage in human cancer cells.
    Duan W; Gao L; Wu X; Zhang Y; Otterson GA; Villalona-Calero MA
    Exp Cell Res; 2006 Oct; 312(17):3370-8. PubMed ID: 16934800
    [TBL] [Abstract][Full Text] [Related]  

  • 13. microRNA-1827 represses MDM2 to positively regulate tumor suppressor p53 and suppress tumorigenesis.
    Zhang C; Liu J; Tan C; Yue X; Zhao Y; Peng J; Wang X; Laddha SV; Chan CS; Zheng S; Hu W; Feng Z
    Oncotarget; 2016 Feb; 7(8):8783-96. PubMed ID: 26840028
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Autoactivation of the MDM2 E3 ligase by intramolecular interaction.
    Cheng Q; Song T; Chen L; Chen J
    Mol Cell Biol; 2014 Aug; 34(15):2800-10. PubMed ID: 24842904
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
    Lu X; Ma O; Nguyen TA; Jones SN; Oren M; Donehower LA
    Cancer Cell; 2007 Oct; 12(4):342-54. PubMed ID: 17936559
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mdm2 links genotoxic stress and metabolism to p53.
    Wang Z; Li B
    Protein Cell; 2010 Dec; 1(12):1063-72. PubMed ID: 21213101
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ATM-mediated phosphorylations inhibit Mdmx/Mdm2 stabilization by HAUSP in favor of p53 activation.
    Meulmeester E; Pereg Y; Shiloh Y; Jochemsen AG
    Cell Cycle; 2005 Sep; 4(9):1166-70. PubMed ID: 16082221
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Influenza A viruses alter the stability and antiviral contribution of host E3-ubiquitin ligase Mdm2 during the time-course of infection.
    Pizzorno A; Dubois J; Machado D; Cartet G; Traversier A; Julien T; Lina B; Bourdon JC; Rosa-Calatrava M; Terrier O
    Sci Rep; 2018 Feb; 8(1):3746. PubMed ID: 29487367
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of ribosomal protein S25 (RPS25)-MDM2-p53 regulatory feedback loop.
    Zhang X; Wang W; Wang H; Wang MH; Xu W; Zhang R
    Oncogene; 2013 May; 32(22):2782-91. PubMed ID: 22777350
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dissecting the p53-Mdm2 feedback loop in vivo: uncoupling the role in p53 stability and activity.
    Pant V; Lozano G
    Oncotarget; 2014 Mar; 5(5):1149-56. PubMed ID: 24658419
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.