BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

886 related articles for article (PubMed ID: 31666108)

  • 1. GSTZ1 deficiency promotes hepatocellular carcinoma proliferation via activation of the KEAP1/NRF2 pathway.
    Li J; Wang Q; Yang Y; Lei C; Yang F; Liang L; Chen C; Xia J; Wang K; Tang N
    J Exp Clin Cancer Res; 2019 Oct; 38(1):438. PubMed ID: 31666108
    [TBL] [Abstract][Full Text] [Related]  

  • 2. GSTZ1-1 Deficiency Activates NRF2/IGF1R Axis in HCC via Accumulation of Oncometabolite Succinylacetone.
    Yang F; Li J; Deng H; Wang Y; Lei C; Wang Q; Xiang J; Liang L; Xia J; Pan X; Li X; Long Q; Chang L; Xu P; Huang A; Wang K; Tang N
    EMBO J; 2019 Aug; 38(15):e101964. PubMed ID: 31267557
    [TBL] [Abstract][Full Text] [Related]  

  • 3. GSTZ1 sensitizes hepatocellular carcinoma cells to sorafenib-induced ferroptosis via inhibition of NRF2/GPX4 axis.
    Wang Q; Bin C; Xue Q; Gao Q; Huang A; Wang K; Tang N
    Cell Death Dis; 2021 Apr; 12(5):426. PubMed ID: 33931597
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SLC27A5 deficiency activates NRF2/TXNRD1 pathway by increased lipid peroxidation in HCC.
    Gao Q; Zhang G; Zheng Y; Yang Y; Chen C; Xia J; Liang L; Lei C; Hu Y; Cai X; Zhang W; Tang H; Chen Y; Huang A; Wang K; Tang N
    Cell Death Differ; 2020 Mar; 27(3):1086-1104. PubMed ID: 31367013
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Ubiquitin E3 Ligase TRIM21 Promotes Hepatocarcinogenesis by Suppressing the p62-Keap1-Nrf2 Antioxidant Pathway.
    Wang F; Zhang Y; Shen J; Yang B; Dai W; Yan J; Maimouni S; Daguplo HQ; Coppola S; Gao Y; Wang Y; Du Z; Peng K; Liu H; Zhang Q; Tang F; Wang P; Gao S; Wang Y; Ding WX; Guo G; Wang F; Zong WX
    Cell Mol Gastroenterol Hepatol; 2021; 11(5):1369-1385. PubMed ID: 33482392
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparative subcellular localization of NRF2 and KEAP1 during the hepatocellular carcinoma development in vivo.
    Guerrero-Escalera D; Alarcón-Sánchez BR; Arellanes-Robledo J; Cruz-Rangel A; Del Pozo-Yauner L; Chagoya de Sánchez V; Resendis-Antonio O; Villa-Treviño S; Torres-Mena JE; Pérez-Carreón JI
    Biochim Biophys Acta Mol Cell Res; 2022 May; 1869(5):119222. PubMed ID: 35093454
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CDCA2 protects against oxidative stress by promoting BRCA1-NRF2 signaling in hepatocellular carcinoma.
    Wang S; Cao K; Liao Y; Zhang W; Zheng J; Li X; Huang M; Zhong Y; Hu X; Chen D; Wang Y
    Oncogene; 2021 Jun; 40(25):4368-4383. PubMed ID: 34103686
    [TBL] [Abstract][Full Text] [Related]  

  • 8. S-1-propenylmercaptocysteine protects murine hepatocytes against oxidative stress via persulfidation of Keap1 and activation of Nrf2.
    Tocmo R; Parkin K
    Free Radic Biol Med; 2019 Nov; 143():164-175. PubMed ID: 31349040
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Association of Peroxiredoxin 4 with the Initiation and Progression of Hepatocellular Carcinoma.
    Guo X; Noguchi H; Ishii N; Homma T; Hamada T; Hiraki T; Zhang J; Matsuo K; Yokoyama S; Ishibashi H; Fukushige T; Kanekura T; Fujii J; Uramoto H; Tanimoto A; Yamada S
    Antioxid Redox Signal; 2019 Apr; 30(10):1271-1284. PubMed ID: 29687726
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TRIM25 promotes the cell survival and growth of hepatocellular carcinoma through targeting Keap1-Nrf2 pathway.
    Liu Y; Tao S; Liao L; Li Y; Li H; Li Z; Lin L; Wan X; Yang X; Chen L
    Nat Commun; 2020 Jan; 11(1):348. PubMed ID: 31953436
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular Mechanisms Underlying Hepatocellular Carcinoma Induction by Aberrant NRF2 Activation-Mediated Transcription Networks: Interaction of NRF2-KEAP1 Controls the Fate of Hepatocarcinogenesis.
    Haque E; Karim MR; Salam Teeli A; Śmiech M; Leszczynski P; Winiarczyk D; Parvanov ED; Atanasov AG; Taniguchi H
    Int J Mol Sci; 2020 Jul; 21(15):. PubMed ID: 32751080
    [TBL] [Abstract][Full Text] [Related]  

  • 12. GSTZ1-1 downregulates Wnt/β-catenin signalling in hepatocellular carcinoma cells.
    Lei C; Wang Q; Tang N; Wang K
    FEBS Open Bio; 2020 Jan; 10(1):6-17. PubMed ID: 31782257
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MiR-141 Activates Nrf2-Dependent Antioxidant Pathway via Down-Regulating the Expression of Keap1 Conferring the Resistance of Hepatocellular Carcinoma Cells to 5-Fluorouracil.
    Shi L; Wu L; Chen Z; Yang J; Chen X; Yu F; Zheng F; Lin X
    Cell Physiol Biochem; 2015; 35(6):2333-48. PubMed ID: 25896253
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MCUR1 facilitates epithelial-mesenchymal transition and metastasis via the mitochondrial calcium dependent ROS/Nrf2/Notch pathway in hepatocellular carcinoma.
    Jin M; Wang J; Ji X; Cao H; Zhu J; Chen Y; Yang J; Zhao Z; Ren T; Xing J
    J Exp Clin Cancer Res; 2019 Mar; 38(1):136. PubMed ID: 30909929
    [TBL] [Abstract][Full Text] [Related]  

  • 15. NRF2 DLG Domain Mutations Identified in Japanese Liver Cancer Patients Affect the Transcriptional Activity in HCC Cell Lines.
    Haque E; Śmiech M; Łuczyńska K; Bouchard MF; Viger R; Kono H; Pierzchała M; Taniguchi H
    Int J Mol Sci; 2021 May; 22(10):. PubMed ID: 34069882
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Neuroglobin, a novel intracellular hexa-coordinated globin, functions as a tumor suppressor in hepatocellular carcinoma via Raf/MAPK/Erk.
    Zhang J; Lan SJ; Liu QR; Liu JM; Chen XQ
    Mol Pharmacol; 2013 May; 83(5):1109-19. PubMed ID: 23478801
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The chemokine receptor CCR10 promotes inflammation-driven hepatocarcinogenesis via PI3K/Akt pathway activation.
    Wu Q; Chen JX; Chen Y; Cai LL; Wang XZ; Guo WH; Zheng JF
    Cell Death Dis; 2018 Feb; 9(2):232. PubMed ID: 29445190
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nrf2 Mutation/Activation Is Dispensable for the Development of Chemically Induced Mouse HCC.
    Mattu S; Zavattari P; Kowalik MA; Serra M; Sulas P; Pal R; Puliga E; Sutti S; Foglia B; Parola M; Albano E; Giordano S; Perra A; Columbano A
    Cell Mol Gastroenterol Hepatol; 2022; 13(1):113-127. PubMed ID: 34530178
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oxidative stress indicated by elevated expression of Nrf2 and 8-OHdG promotes hepatocellular carcinoma progression.
    Ma-On C; Sanpavat A; Whongsiri P; Suwannasin S; Hirankarn N; Tangkijvanich P; Boonla C
    Med Oncol; 2017 Apr; 34(4):57. PubMed ID: 28281193
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dysregulated glucuronic acid metabolism exacerbates hepatocellular carcinoma progression and metastasis through the TGFβ signalling pathway.
    Gao Q; Cheng B; Chen C; Lei C; Lin X; Nie D; Li J; Huang L; Li X; Wang K; Huang A; Tang N
    Clin Transl Med; 2022 Aug; 12(8):e995. PubMed ID: 35979621
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 45.