BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

348 related articles for article (PubMed ID: 31666694)

  • 1. Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs.
    Flavahan WA; Drier Y; Johnstone SE; Hemming ML; Tarjan DR; Hegazi E; Shareef SJ; Javed NM; Raut CP; Eschle BK; Gokhale PC; Hornick JL; Sicinska ET; Demetri GD; Bernstein BE
    Nature; 2019 Nov; 575(7781):229-233. PubMed ID: 31666694
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gene duplication, rather than epigenetic changes, drives FGF4 overexpression in KIT/PDGFRA/SDH/RAS-P WT GIST.
    Urbini M; Astolfi A; Indio V; Nannini M; Schipani A; Bacalini MG; Angelini S; Ravegnini G; Calice G; Del Gaudio M; Secchiero P; Ulivi P; Gruppioni E; Pantaleo MA
    Sci Rep; 2020 Nov; 10(1):19829. PubMed ID: 33199729
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Succinate dehydrogenase deficiency is associated with decreased 5-hydroxymethylcytosine production in gastrointestinal stromal tumors: implications for mechanisms of tumorigenesis.
    Mason EF; Hornick JL
    Mod Pathol; 2013 Nov; 26(11):1492-7. PubMed ID: 23743927
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Preferential MGMT methylation could predispose a subset of KIT/PDGFRA-WT GISTs, including SDH-deficient ones, to respond to alkylating agents.
    Ricci R; Martini M; Ravegnini G; Cenci T; Milione M; Lanza P; Pierconti F; Santini D; Angelini S; Biondi A; Rosa F; Alfieri S; Clemente G; Persiani R; Cassano A; Pantaleo MA; Larocca LM
    Clin Epigenetics; 2019 Jan; 11(1):2. PubMed ID: 30616628
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genetic and epigenetic alterations of SDH genes in patients with sporadic succinate dehydrogenase-deficient gastrointestinal stromal tumors.
    Shi SS; Wang YF; Bao W; Ye SB; Wu N; Wang X; Xia QY; Li R; Shen Q; Zhou XJ
    Pathol Int; 2019 Jun; 69(6):350-359. PubMed ID: 31273876
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Succinate dehydrogenase deficient gastrointestinal stromal tumors (GISTs) - a review.
    Miettinen M; Lasota J
    Int J Biochem Cell Biol; 2014 Aug; 53():514-9. PubMed ID: 24886695
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular Subtypes of KIT/PDGFRA Wild-Type Gastrointestinal Stromal Tumors: A Report From the National Institutes of Health Gastrointestinal Stromal Tumor Clinic.
    Boikos SA; Pappo AS; Killian JK; LaQuaglia MP; Weldon CB; George S; Trent JC; von Mehren M; Wright JA; Schiffman JD; Raygada M; Pacak K; Meltzer PS; Miettinen MM; Stratakis C; Janeway KA; Helman LJ
    JAMA Oncol; 2016 Jul; 2(7):922-8. PubMed ID: 27011036
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gain of FGF4 is a frequent event in KIT/PDGFRA/SDH/RAS-P WT GIST.
    Urbini M; Indio V; Tarantino G; Ravegnini G; Angelini S; Nannini M; Saponara M; Santini D; Ceccarelli C; Fiorentino M; Vincenzi B; Fumagalli E; Casali PG; Grignani G; Pession A; Ardizzoni A; Astolfi A; Pantaleo MA
    Genes Chromosomes Cancer; 2019 Sep; 58(9):636-642. PubMed ID: 30887595
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gastrointestinal stromal tumors - Summary of mutational status of the primary/secondary KIT/PDGFRA mutations, BRAF mutations and SDH defects.
    Kalfusova A; Linke Z; Kalinova M; Krskova L; Hilska I; Szabova J; Vicha A; Kodet R
    Pathol Res Pract; 2019 Dec; 215(12):152708. PubMed ID: 31708372
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Succinate dehydrogenase deficiency in a PDGFRA mutated GIST.
    Belinsky MG; Cai KQ; Zhou Y; Luo B; Pei J; Rink L; von Mehren M
    BMC Cancer; 2017 Aug; 17(1):512. PubMed ID: 28768491
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Succinate dehydrogenase-deficient gastrointestinal stromal tumors.
    Wang YM; Gu ML; Ji F
    World J Gastroenterol; 2015 Feb; 21(8):2303-14. PubMed ID: 25741136
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Current management of succinate dehydrogenase-deficient gastrointestinal stromal tumors.
    Neppala P; Banerjee S; Fanta PT; Yerba M; Porras KA; Burgoyne AM; Sicklick JK
    Cancer Metastasis Rev; 2019 Sep; 38(3):525-535. PubMed ID: 31773431
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations.
    Janeway KA; Kim SY; Lodish M; Nosé V; Rustin P; Gaal J; Dahia PL; Liegl B; Ball ER; Raygada M; Lai AH; Kelly L; Hornick JL; ; O'Sullivan M; de Krijger RR; Dinjens WN; Demetri GD; Antonescu CR; Fletcher JA; Helman L; Stratakis CA
    Proc Natl Acad Sci U S A; 2011 Jan; 108(1):314-8. PubMed ID: 21173220
    [TBL] [Abstract][Full Text] [Related]  

  • 14. KIT mutation in a naïve succinate dehydrogenase-deficient gastric GIST.
    Brcic I; Kashofer K; Skone D; Liegl-Atzwanger B
    Genes Chromosomes Cancer; 2019 Nov; 58(11):798-803. PubMed ID: 31124195
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Succinate dehydrogenase-deficient GISTs: a clinicopathologic, immunohistochemical, and molecular genetic study of 66 gastric GISTs with predilection to young age.
    Miettinen M; Wang ZF; Sarlomo-Rikala M; Osuch C; Rutkowski P; Lasota J
    Am J Surg Pathol; 2011 Nov; 35(11):1712-21. PubMed ID: 21997692
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Expression of succinate dehydrogenase subunit protein in succinate dehydrogenase-deficient gastrointestinal stromal tumors].
    Zhang YJ; Cheng YH; Guo LX; Wang NQ; Liu H
    Zhonghua Bing Li Xue Za Zhi; 2018 Apr; 47(4):252-257. PubMed ID: 29690663
    [No Abstract]   [Full Text] [Related]  

  • 17. Loss of succinate dehydrogenase subunit B (SDHB) expression is limited to a distinctive subset of gastric wild-type gastrointestinal stromal tumours: a comprehensive genotype-phenotype correlation study.
    Doyle LA; Nelson D; Heinrich MC; Corless CL; Hornick JL
    Histopathology; 2012 Nov; 61(5):801-9. PubMed ID: 22804613
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gastrointestinal Stromal Tumors: The GIST of Precision Medicine.
    Mei L; Smith SC; Faber AC; Trent J; Grossman SR; Stratakis CA; Boikos SA
    Trends Cancer; 2018 Jan; 4(1):74-91. PubMed ID: 29413424
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A Duodenal SDH-Deficient Gastrointestinal Stromal Tumor in a Patient With a Germline SDHB Mutation.
    Elston MS; Sehgal S; Dray M; Phillips E; Conaglen JV; Clifton-Bligh RJ; Gill AJ
    J Clin Endocrinol Metab; 2017 May; 102(5):1447-1450. PubMed ID: 28324028
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Loss of SDHA expression identifies SDHA mutations in succinate dehydrogenase-deficient gastrointestinal stromal tumors.
    Dwight T; Benn DE; Clarkson A; Vilain R; Lipton L; Robinson BG; Clifton-Bligh RJ; Gill AJ
    Am J Surg Pathol; 2013 Feb; 37(2):226-33. PubMed ID: 23060355
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.