BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

839 related articles for article (PubMed ID: 31669234)

  • 1. Delicaflavone induces ROS-mediated apoptosis and inhibits PI3K/AKT/mTOR and Ras/MEK/Erk signaling pathways in colorectal cancer cells.
    Yao W; Lin Z; Shi P; Chen B; Wang G; Huang J; Sui Y; Liu Q; Li S; Lin X; Liu Q; Yao H
    Biochem Pharmacol; 2020 Jan; 171():113680. PubMed ID: 31669234
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Delicaflavone induces apoptosis via mitochondrial pathway accompanying G2/M cycle arrest and inhibition of MAPK signaling cascades in cervical cancer HeLa cells.
    Yao W; Lin Z; Wang G; Li S; Chen B; Sui Y; Huang J; Liu Q; Shi P; Lin X; Liu Q; Yao H
    Phytomedicine; 2019 Sep; 62():152973. PubMed ID: 31177019
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Deoxyshikonin isolated from
    Zhu Y; Zhong Y; Long X; Zhu Z; Zhou Y; Ye H; Zeng X; Zheng X
    Pharm Biol; 2019 Dec; 57(1):412-423. PubMed ID: 31230505
    [No Abstract]   [Full Text] [Related]  

  • 4. Zeylenone, a naturally occurring cyclohexene oxide, inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways.
    Zhang L; Huo X; Liao Y; Yang F; Gao L; Cao L
    Sci Rep; 2017 May; 7(1):1669. PubMed ID: 28490807
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Delicaflavone induces autophagic cell death in lung cancer via Akt/mTOR/p70S6K signaling pathway.
    Sui Y; Yao H; Li S; Jin L; Shi P; Li Z; Wang G; Lin S; Wu Y; Li Y; Huang L; Liu Q; Lin X
    J Mol Med (Berl); 2017 Mar; 95(3):311-322. PubMed ID: 27838742
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Atractylenolide I inhibits colorectal cancer cell proliferation by affecting metabolism and stemness via AKT/mTOR signaling.
    Wang K; Huang W; Sang X; Wu X; Shan Q; Tang D; Xu X; Cao G
    Phytomedicine; 2020 Mar; 68():153191. PubMed ID: 32135457
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthetic lethal interaction between PI3K/Akt/mTOR and Ras/MEK/ERK pathway inhibition in rhabdomyosarcoma.
    Guenther MK; Graab U; Fulda S
    Cancer Lett; 2013 Sep; 337(2):200-9. PubMed ID: 23684925
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Des-gamma-carboxy prothrombin antagonizes the effects of Sorafenib on human hepatocellular carcinoma through activation of the Raf/MEK/ERK and PI3K/Akt/mTOR signaling pathways.
    Cui SX; Shi WN; Song ZY; Wang SQ; Yu XF; Gao ZH; Qu XJ
    Oncotarget; 2016 Jun; 7(24):36767-36782. PubMed ID: 27167344
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK; Wang ZL; Pan ST; Ding HQ; Au GH; He ZX; Zhou ZW; Xiao G; Yang YX; Zhang X; Yang T; Chen XW; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1555-84. PubMed ID: 25792811
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Linalool induces cell cycle arrest and apoptosis in HepG2 cells through oxidative stress generation and modulation of Ras/MAPK and Akt/mTOR pathways.
    Rodenak-Kladniew B; Castro A; Stärkel P; De Saeger C; García de Bravo M; Crespo R
    Life Sci; 2018 Apr; 199():48-59. PubMed ID: 29510199
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Coptisine-induced apoptosis in human colon cancer cells (HCT-116) is mediated by PI3K/Akt and mitochondrial-associated apoptotic pathway.
    Han B; Jiang P; Li Z; Yu Y; Huang T; Ye X; Li X
    Phytomedicine; 2018 Sep; 48():152-160. PubMed ID: 30195873
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NSK-01105 inhibits proliferation and induces apoptosis of prostate cancer cells by blocking the Raf/MEK/ERK and PI3K/Akt/mTOR signal pathways.
    Yu P; Ye L; Wang H; Du G; Zhang J; Zhang J; Tian J
    Tumour Biol; 2015 Mar; 36(3):2143-53. PubMed ID: 25398692
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antitumor activity of pimasertib, a selective MEK 1/2 inhibitor, in combination with PI3K/mTOR inhibitors or with multi-targeted kinase inhibitors in pimasertib-resistant human lung and colorectal cancer cells.
    Martinelli E; Troiani T; D'Aiuto E; Morgillo F; Vitagliano D; Capasso A; Costantino S; Ciuffreda LP; Merolla F; Vecchione L; De Vriendt V; Tejpar S; Nappi A; Sforza V; Martini G; Berrino L; De Palma R; Ciardiello F
    Int J Cancer; 2013 Nov; 133(9):2089-101. PubMed ID: 23629727
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ethyl acetate extract from Selaginella doederleinii Hieron inhibits the growth of human lung cancer cells A549 via caspase-dependent apoptosis pathway.
    Sui Y; Li S; Shi P; Wu Y; Li Y; Chen W; Huang L; Yao H; Lin X
    J Ethnopharmacol; 2016 Aug; 190():261-71. PubMed ID: 27292193
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of Autophagy Promotes Salinomycin-Induced Apoptosis via Reactive Oxygen Species-Mediated PI3K/AKT/mTOR and ERK/p38 MAPK-Dependent Signaling in Human Prostate Cancer Cells.
    Kim KY; Park KI; Kim SH; Yu SN; Park SG; Kim YW; Seo YK; Ma JY; Ahn SC
    Int J Mol Sci; 2017 May; 18(5):. PubMed ID: 28524116
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lycorine inhibits cell proliferation, migration and invasion, and primarily exerts
    Zhang P; Yuan X; Yu T; Huang H; Yang C; Zhang L; Yang S; Luo X; Luo J
    Oncol Rep; 2021 Apr; 45(4):. PubMed ID: 33649853
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PI3K/Akt/mTOR and Ras/Raf/MEK/ERK signaling pathways inhibitors as anticancer agents: Structural and pharmacological perspectives.
    Asati V; Mahapatra DK; Bharti SK
    Eur J Med Chem; 2016 Feb; 109():314-41. PubMed ID: 26807863
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Anti-breast cancer and toxicity studies of total secondary saponin from Anemone raddeana Rhizome on MCF-7 cells via ROS generation and PI3K/AKT/mTOR inactivation.
    Zhang D; Zhang Q; Zheng Y; Lu J
    J Ethnopharmacol; 2020 Sep; 259():112984. PubMed ID: 32446927
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Piperlongumine, a piper alkaloid targets Ras/PI3K/Akt/mTOR signaling axis to inhibit tumor cell growth and proliferation in DMH/DSS induced experimental colon cancer.
    Kumar S; Agnihotri N
    Biomed Pharmacother; 2019 Jan; 109():1462-1477. PubMed ID: 30551398
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NO donor inhibits proliferation and induces apoptosis by targeting PI3K/AKT/mTOR and MEK/ERK pathways in hepatocellular carcinoma cells.
    Liu L; Chen J; Cao M; Wang J; Wang S
    Cancer Chemother Pharmacol; 2019 Dec; 84(6):1303-1314. PubMed ID: 31555866
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 42.