These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 31670965)

  • 1. Establishment of an In Vitro-In Vivo Correlation for Melanin Binding and the Extension of the Ocular Half-Life of Small-Molecule Drugs.
    Jakubiak P; Cantrill C; Urtti A; Alvarez-Sánchez R
    Mol Pharm; 2019 Dec; 16(12):4890-4901. PubMed ID: 31670965
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Drug Distribution to Retinal Pigment Epithelium: Studies on Melanin Binding, Cellular Kinetics, and Single Photon Emission Computed Tomography/Computed Tomography Imaging.
    Rimpelä AK; Schmitt M; Latonen S; Hagström M; Antopolsky M; Manzanares JA; Kidron H; Urtti A
    Mol Pharm; 2016 Sep; 13(9):2977-86. PubMed ID: 26741026
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Implications of melanin binding in ocular drug delivery.
    Rimpelä AK; Reinisalo M; Hellinen L; Grazhdankin E; Kidron H; Urtti A; Del Amo EM
    Adv Drug Deliv Rev; 2018 Feb; 126():23-43. PubMed ID: 29247767
    [TBL] [Abstract][Full Text] [Related]  

  • 4. High-Throughput Melanin-Binding Affinity and In Silico Methods to Aid in the Prediction of Drug Exposure in Ocular Tissue.
    Reilly J; Williams SL; Forster CJ; Kansara V; End P; Serrano-Wu MH
    J Pharm Sci; 2015 Dec; 104(12):3997-4001. PubMed ID: 26524700
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Melanin targeting for intracellular drug delivery: Quantification of bound and free drug in retinal pigment epithelial cells.
    Rimpelä AK; Hagström M; Kidron H; Urtti A
    J Control Release; 2018 Aug; 283():261-268. PubMed ID: 29859954
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanisms of cellular retention of melanin bound drugs: Experiments and computational modeling.
    Bahrpeyma S; Reinisalo M; Hellinen L; Auriola S; Del Amo EM; Urtti A
    J Control Release; 2022 Aug; 348():760-770. PubMed ID: 35738465
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Influence of Melanin Characteristics on Drug Binding Properties.
    Jakubiak P; Lack F; Thun J; Urtti A; Alvarez-Sánchez R
    Mol Pharm; 2019 Jun; 16(6):2549-2556. PubMed ID: 30998378
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Melanin binding study of clinical drugs with cassette dosing and rapid equilibrium dialysis inserts.
    Pelkonen L; Tengvall-Unadike U; Ruponen M; Kidron H; Del Amo EM; Reinisalo M; Urtti A
    Eur J Pharm Sci; 2017 Nov; 109():162-168. PubMed ID: 28756205
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Absorption, distribution and excretion of 14C-chloroquine after single oral administration in albino and pigmented rats: binding characteristics of chloroquine-related radioactivity to melanin in-vivo.
    Ono C; Yamada M; Tanaka M
    J Pharm Pharmacol; 2003 Dec; 55(12):1647-54. PubMed ID: 14738591
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Binding of drugs to eye melanin is not predictive of ocular toxicity.
    Leblanc B; Jezequel S; Davies T; Hanton G; Taradach C
    Regul Toxicol Pharmacol; 1998 Oct; 28(2):124-32. PubMed ID: 9927562
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Physicochemical factors associated with binding and retention of compounds in ocular melanin of rats: correlations using data from whole-body autoradiography and molecular modeling for multiple linear regression analyses.
    Zane PA; Brindle SD; Gause DO; O'Buck AJ; Raghavan PR; Tripp SL
    Pharm Res; 1990 Sep; 7(9):935-41. PubMed ID: 2235893
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ex vivo models to evaluate the role of ocular melanin in trans-scleral drug delivery.
    Pescina S; Santi P; Ferrari G; Padula C; Cavallini P; Govoni P; Nicoli S
    Eur J Pharm Sci; 2012 Aug; 46(5):475-83. PubMed ID: 22484210
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Absorption, distribution and excretion of 14C-levofloxacin after single oral administration in albino and pigmented rats: binding characteristics of levofloxacin-related radioactivity to melanin in vivo.
    Tanaka M; Ono C; Yamada M
    J Pharm Pharmacol; 2004 Apr; 56(4):463-9. PubMed ID: 15099441
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The effect of ocular pigmentation on transscleral delivery of triamcinolone acetonide.
    Du W; Sun S; Xu Y; Li J; Zhao C; Lan B; Chen H; Cheng L
    J Ocul Pharmacol Ther; 2013 Sep; 29(7):633-8. PubMed ID: 23597073
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of eye pigmentation on transscleral drug delivery.
    Cheruvu NP; Amrite AC; Kompella UB
    Invest Ophthalmol Vis Sci; 2008 Jan; 49(1):333-41. PubMed ID: 18172110
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The melanin binding of bisoprolol and its toxicological relevance.
    Steiner K; Bühring KU; Merck E
    Lens Eye Toxic Res; 1990; 7(3-4):319-33. PubMed ID: 1983104
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of a Phototoxicity Testing Strategy for Accurate Photosafety Evaluation of Pharmaceuticals Based on the Assessment of Possible Melanin-Binding Effects.
    Reinen J; van Sas P; van Huygevoort T; Rubio L; Scase K; Wenker M
    Int J Toxicol; 2018; 37(4):296-307. PubMed ID: 29898631
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Binding of antiglaucomatous drugs to synthetic melanin and their hypotensive effects on pigmented and nonpigmented rabbit eyes.
    Nagata A; Mishima HK; Kiuchi Y; Hirota A; Kurokawa T; Ishibashi S
    Jpn J Ophthalmol; 1993; 37(1):32-8. PubMed ID: 8100592
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Understanding Molecular Drivers of Melanin Binding To Support Rational Design of Small Molecule Ophthalmic Drugs.
    Jakubiak P; Reutlinger M; Mattei P; Schuler F; Urtti A; Alvarez-Sánchez R
    J Med Chem; 2018 Nov; 61(22):10106-10115. PubMed ID: 30398862
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Binding of 14C-spermidine to melanin in vivo and in vitro.
    Tjälve H; Nilsson M; Larsson B
    Acta Physiol Scand; 1981 Jun; 112(2):209-14. PubMed ID: 7315415
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.