BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

672 related articles for article (PubMed ID: 31674147)

  • 1. Synthesis of Combretastatin-A4 Carboxamidest that Mimic Sulfonyl Piperazines by a Molecular Hybridization Approach: in vitro Cytotoxicity Evaluation and Inhibition of Tubulin Polymerization.
    Jadala C; Sathish M; Anchi P; Tokala R; Lakshmi UJ; Reddy VG; Shankaraiah N; Godugu C; Kamal A
    ChemMedChem; 2019 Dec; 14(24):2052-2060. PubMed ID: 31674147
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T; Mikstacka R; Kurczab R; Dutkiewicz Z; Kucińska M; Murias M; Zielińska-Przyjemska M; Cichocki M; Teubert A; Kaczmarek M; Hogendorf A; Sobiak S
    Eur J Med Chem; 2018 Jan; 144():797-816. PubMed ID: 29291446
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis of combretastatin A-4 piperazine derivatives as potential antitumor agents by inhibiting tubulin polymerization and inducing autophagy in HCT116 cells.
    Zhang H; Li M; Zhou X; Tang L; Chen G; Zhang Y
    Eur J Med Chem; 2024 Jun; 272():116497. PubMed ID: 38759453
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect.
    Ibrahim TS; Hawwas MM; Malebari AM; Taher ES; Omar AM; Neamatallah T; Abdel-Samii ZK; Safo MK; Elshaier YAMM
    J Enzyme Inhib Med Chem; 2021 Dec; 36(1):802-818. PubMed ID: 33730937
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and evaluation of antiproliferative microtubule-destabilising combretastatin A-4 piperazine conjugates.
    O'Boyle NM; Ana G; Kelly PM; Nathwani SM; Noorani S; Fayne D; Bright SA; Twamley B; Zisterer DM; Meegan MJ
    Org Biomol Chem; 2019 Jun; 17(25):6184-6200. PubMed ID: 31173031
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors.
    Behbahani FS; Tabeshpour J; Mirzaei S; Golmakaniyoon S; Tayarani-Najaran Z; Ghasemi A; Ghodsi R
    Arch Pharm (Weinheim); 2019 Jun; 352(6):e1800307. PubMed ID: 31012156
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH; Dahab MA; Ibrahim MK; Alsaif NA; Alanazi AZ; Eissa SI; Mehany ABM; Beauchemin AM
    Bioorg Chem; 2021 Jul; 112():104965. PubMed ID: 34020238
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, antiproliferative, anti-tubulin activity, and docking study of new 1,2,4-triazoles as potential combretastatin analogues.
    Mustafa M; Abdelhamid D; Abdelhafez EMN; Ibrahim MAA; Gamal-Eldeen AM; Aly OM
    Eur J Med Chem; 2017 Dec; 141():293-305. PubMed ID: 29031074
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis and biological evaluation of novel imidazole-chalcone derivatives as potential anticancer agents and tubulin polymerization inhibitors.
    Rahimzadeh Oskuei S; Mirzaei S; Reza Jafari-Nik M; Hadizadeh F; Eisvand F; Mosaffa F; Ghodsi R
    Bioorg Chem; 2021 Jul; 112():104904. PubMed ID: 33933802
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
    Zhou P; Liang Y; Zhang H; Jiang H; Feng K; Xu P; Wang J; Wang X; Ding K; Luo C; Liu M; Wang Y
    Eur J Med Chem; 2018 Jan; 144():817-842. PubMed ID: 29306206
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Combretastatin linked 1,3,4-oxadiazole conjugates as a Potent Tubulin Polymerization inhibitors.
    Kamal A; Srikanth PS; Vishnuvardhan MV; Kumar GB; Suresh Babu K; Hussaini SM; Kapure JS; Alarifi A
    Bioorg Chem; 2016 Apr; 65():126-36. PubMed ID: 26943479
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sulfamic acid promoted one-pot synthesis of phenanthrene fused-dihydrodibenzo-quinolinones: Anticancer activity, tubulin polymerization inhibition and apoptosis inducing studies.
    Kumar NP; Thatikonda S; Tokala R; Kumari SS; Lakshmi UJ; Godugu C; Shankaraiah N; Kamal A
    Bioorg Med Chem; 2018 May; 26(8):1996-2008. PubMed ID: 29525336
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Potent combretastatin A-4 analogs containing 1,2,4-triazole: Synthesis, antiproliferative, anti-tubulin activity, and docking study.
    Mustafa M; Anwar S; Elgamal F; Ahmed ER; Aly OM
    Eur J Med Chem; 2019 Dec; 183():111697. PubMed ID: 31536891
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel Combretastatin A-4 Analogs-Design, Synthesis, and Antiproliferative and Anti-Tubulin Activity.
    Jędrzejczyk M; Morabito B; Żyżyńska-Granica B; Struga M; Janczak J; Aminpour M; Tuszynski JA; Huczyński A
    Molecules; 2024 May; 29(10):. PubMed ID: 38792062
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A 2-step synthesis of Combretastatin A-4 and derivatives as potent tubulin assembly inhibitors.
    Barnes NG; Parker AW; Ahmed Mal Ullah AA; Ragazzon PA; Hadfield JA
    Bioorg Med Chem; 2020 Oct; 28(19):115684. PubMed ID: 32912434
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design and synthesis of substituted dihydropyrimidinone derivatives as cytotoxic and tubulin polymerization inhibitors.
    Sana S; Tokala R; Bajaj DM; Nagesh N; Bokara KK; Kiranmai G; Lakshmi UJ; Vadlamani S; Talla V; Shankaraiah N
    Bioorg Chem; 2019 Dec; 93():103317. PubMed ID: 31586714
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological evaluation of curcumin inspired imidazo[1,2-a]pyridine analogues as tubulin polymerization inhibitors.
    Ramya PVS; Guntuku L; Angapelly S; Digwal CS; Lakshmi UJ; Sigalapalli DK; Babu BN; Naidu VGM; Kamal A
    Eur J Med Chem; 2018 Jan; 143():216-231. PubMed ID: 29174816
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Anti-proliferative potential of triphenyl substituted pyrimidines against MDA-MB-231, HCT-116 and HT-29 cancer cell lines.
    Ranjan Dwivedi A; Kumar V; Kaur H; Kumar N; Prakash Yadav R; Poduri R; Baranwal S; Kumar V
    Bioorg Med Chem Lett; 2020 Oct; 30(20):127468. PubMed ID: 32768647
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New thiazole-2(3H)-thiones containing 4-(3,4,5-trimethoxyphenyl) moiety as anticancer agents.
    Ansari M; Shokrzadeh M; Karima S; Rajaei S; Fallah M; Ghassemi-Barghi N; Ghasemian M; Emami S
    Eur J Med Chem; 2020 Jan; 185():111784. PubMed ID: 31669850
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological evaluation of 1-benzyl-N-(2-(phenylamino)pyridin-3-yl)-1H-1,2,3-triazole-4-carboxamides as antimitotic agents.
    Prasad B; Lakshma Nayak V; Srikanth PS; Baig MF; Subba Reddy NV; Babu KS; Kamal A
    Bioorg Chem; 2019 Mar; 83():535-548. PubMed ID: 30472555
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.