BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 31676673)

  • 1. Folliculin Interacting Protein 1 Maintains Metabolic Homeostasis during B Cell Development by Modulating AMPK, mTORC1, and TFE3.
    Ramírez JA; Iwata T; Park H; Tsang M; Kang J; Cui K; Kwong W; James RG; Baba M; Schmidt LS; Iritani BM
    J Immunol; 2019 Dec; 203(11):2899-2908. PubMed ID: 31676673
    [TBL] [Abstract][Full Text] [Related]  

  • 2. AMPK-dependent phosphorylation is required for transcriptional activation of TFEB and TFE3.
    Paquette M; El-Houjeiri L; C Zirden L; Puustinen P; Blanchette P; Jeong H; Dejgaard K; Siegel PM; Pause A
    Autophagy; 2021 Dec; 17(12):3957-3975. PubMed ID: 33734022
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity.
    Siggs OM; Stockenhuber A; Deobagkar-Lele M; Bull KR; Crockford TL; Kingston BL; Crawford G; Anzilotti C; Steeples V; Ghaffari S; Czibik G; Bellahcene M; Watkins H; Ashrafian H; Davies B; Woods A; Carling D; Yavari A; Beutler B; Cornall RJ
    Proc Natl Acad Sci U S A; 2016 Jun; 113(26):E3706-15. PubMed ID: 27303042
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Loss of Fnip1 alters kidney developmental transcriptional program and synergizes with TSC1 loss to promote mTORC1 activation and renal cyst formation.
    Centini R; Tsang M; Iwata T; Park H; Delrow J; Margineantu D; Iritani BM; Gu H; Liggitt HD; Kang J; Kang L; Hockenbery DM; Raftery D; Iritani BM
    PLoS One; 2018; 13(6):e0197973. PubMed ID: 29897930
    [TBL] [Abstract][Full Text] [Related]  

  • 5. AKT inhibition-mediated dephosphorylation of TFE3 promotes overactive autophagy independent of MTORC1 in cadmium-exposed bone mesenchymal stem cells.
    Pi H; Li M; Zou L; Yang M; Deng P; Fan T; Liu M; Tian L; Tu M; Xie J; Chen M; Li H; Xi Y; Zhang L; He M; Lu Y; Chen C; Zhang T; Wang Z; Yu Z; Gao F; Zhou Z
    Autophagy; 2019 Apr; 15(4):565-582. PubMed ID: 30324847
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolic regulator Fnip1 is crucial for iNKT lymphocyte development.
    Park H; Tsang M; Iritani BM; Bevan MJ
    Proc Natl Acad Sci U S A; 2014 May; 111(19):7066-71. PubMed ID: 24785297
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling.
    Baba M; Hong SB; Sharma N; Warren MB; Nickerson ML; Iwamatsu A; Esposito D; Gillette WK; Hopkins RF; Hartley JL; Furihata M; Oishi S; Zhen W; Burke TR; Linehan WM; Schmidt LS; Zbar B
    Proc Natl Acad Sci U S A; 2006 Oct; 103(42):15552-7. PubMed ID: 17028174
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Folliculin impairs breast tumor growth by repressing TFE3-dependent induction of the Warburg effect and angiogenesis.
    El-Houjeiri L; Biondini M; Paquette M; Kuasne H; Pacis A; Park M; Siegel PM; Pause A
    J Clin Invest; 2021 Nov; 131(22):. PubMed ID: 34779410
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Transcription Factors TFEB and TFE3 Link the FLCN-AMPK Signaling Axis to Innate Immune Response and Pathogen Resistance.
    El-Houjeiri L; Possik E; Vijayaraghavan T; Paquette M; Martina JA; Kazan JM; Ma EH; Jones R; Blanchette P; Puertollano R; Pause A
    Cell Rep; 2019 Mar; 26(13):3613-3628.e6. PubMed ID: 30917316
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The anti-tumor agent, Dp44mT, promotes nuclear translocation of TFEB via inhibition of the AMPK-mTORC1 axis.
    Krishan S; Sahni S; Richardson DR
    Biochim Biophys Acta Mol Basis Dis; 2020 Dec; 1866(12):165970. PubMed ID: 32950675
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Direct regulation of FNIP1 and FNIP2 by MEF2 sustains MTORC1 activation and tumor progression in pancreatic cancer.
    Xia L; Nie T; Lu F; Huang L; Shi X; Ren D; Lu J; Li X; Xu T; Cui B; Wang Q; Gao G; Yang Q
    Autophagy; 2024 Mar; 20(3):505-524. PubMed ID: 37772772
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Folliculin: A Regulator of Transcription Through AMPK and mTOR Signaling Pathways.
    Ramirez Reyes JMJ; Cuesta R; Pause A
    Front Cell Dev Biol; 2021; 9():667311. PubMed ID: 33981707
    [No Abstract]   [Full Text] [Related]  

  • 13. A substrate-specific mTORC1 pathway underlies Birt-Hogg-Dubé syndrome.
    Napolitano G; Di Malta C; Esposito A; de Araujo MEG; Pece S; Bertalot G; Matarese M; Benedetti V; Zampelli A; Stasyk T; Siciliano D; Venuta A; Cesana M; Vilardo C; Nusco E; Monfregola J; Calcagnì A; Di Fiore PP; Huber LA; Ballabio A
    Nature; 2020 Sep; 585(7826):597-602. PubMed ID: 32612235
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Folliculin promotes substrate-selective mTORC1 activity by activating RagC to recruit TFE3.
    Li K; Wada S; Gosis BS; Thorsheim C; Loose P; Arany Z
    PLoS Biol; 2022 Mar; 20(3):e3001594. PubMed ID: 35358174
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Double Negative Feedback Loop between mTORC1 and AMPK Kinases Guarantees Precise Autophagy Induction upon Cellular Stress.
    Holczer M; Hajdú B; Lőrincz T; Szarka A; Bánhegyi G; Kapuy O
    Int J Mol Sci; 2019 Nov; 20(22):. PubMed ID: 31703252
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Control of B lymphocyte development and functions by the mTOR signaling pathways.
    Iwata TN; Ramírez-Komo JA; Park H; Iritani BM
    Cytokine Growth Factor Rev; 2017 Jun; 35():47-62. PubMed ID: 28583723
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Birt-Hogg-Dubé syndrome: Clinical and molecular aspects of recently identified kidney cancer syndrome.
    Hasumi H; Baba M; Hasumi Y; Furuya M; Yao M
    Int J Urol; 2016 Mar; 23(3):204-10. PubMed ID: 26608100
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MITF-MIR211 axis is a novel autophagy amplifier system during cellular stress.
    Ozturk DG; Kocak M; Akcay A; Kinoglu K; Kara E; Buyuk Y; Kazan H; Gozuacik D
    Autophagy; 2019 Mar; 15(3):375-390. PubMed ID: 30290719
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The anti-tubercular activity of simvastatin is mediated by cholesterol-driven autophagy via the AMPK-mTORC1-TFEB axis.
    Bruiners N; Dutta NK; Guerrini V; Salamon H; Yamaguchi KD; Karakousis PC; Gennaro ML
    J Lipid Res; 2020 Dec; 61(12):1617-1628. PubMed ID: 32848049
    [TBL] [Abstract][Full Text] [Related]  

  • 20. AMPK promotes induction of the tumor suppressor FLCN through activation of TFEB independently of mTOR.
    Collodet C; Foretz M; Deak M; Bultot L; Metairon S; Viollet B; Lefebvre G; Raymond F; Parisi A; Civiletto G; Gut P; Descombes P; Sakamoto K
    FASEB J; 2019 Nov; 33(11):12374-12391. PubMed ID: 31404503
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.