230 related articles for article (PubMed ID: 31676828)
1. LSD1-mediated repression of GFI1 super-enhancer plays an essential role in erythroleukemia.
Tatsumi G; Kawahara M; Yamamoto R; Hishizawa M; Kito K; Suzuki T; Takaori-Kondo A; Andoh A
Leukemia; 2020 Mar; 34(3):746-758. PubMed ID: 31676828
[TBL] [Abstract][Full Text] [Related]
2. A novel LSD1 inhibitor NCD38 ameliorates MDS-related leukemia with complex karyotype by attenuating leukemia programs via activating super-enhancers.
Sugino N; Kawahara M; Tatsumi G; Kanai A; Matsui H; Yamamoto R; Nagai Y; Fujii S; Shimazu Y; Hishizawa M; Inaba T; Andoh A; Suzuki T; Takaori-Kondo A
Leukemia; 2017 Nov; 31(11):2303-2314. PubMed ID: 28210006
[TBL] [Abstract][Full Text] [Related]
3. Selective dissociation between LSD1 and GFI1B by a LSD1 inhibitor NCD38 induces the activation of
Yamamoto R; Kawahara M; Ito S; Satoh J; Tatsumi G; Hishizawa M; Suzuki T; Andoh A
Oncotarget; 2018 Apr; 9(30):21007-21021. PubMed ID: 29765516
[TBL] [Abstract][Full Text] [Related]
4. Enhancer Activation by Pharmacologic Displacement of LSD1 from GFI1 Induces Differentiation in Acute Myeloid Leukemia.
Maiques-Diaz A; Spencer GJ; Lynch JT; Ciceri F; Williams EL; Amaral FMR; Wiseman DH; Harris WJ; Li Y; Sahoo S; Hitchin JR; Mould DP; Fairweather EE; Waszkowycz B; Jordan AM; Smith DL; Somervaille TCP
Cell Rep; 2018 Mar; 22(13):3641-3659. PubMed ID: 29590629
[TBL] [Abstract][Full Text] [Related]
5. LSD1 defines erythroleukemia metabolism by controlling the lineage-specific transcription factors GATA1 and C/EBPα.
Kohrogi K; Hino S; Sakamoto A; Anan K; Takase R; Araki H; Hino Y; Araki K; Sato T; Nakamura K; Nakao M
Blood Adv; 2021 May; 5(9):2305-2318. PubMed ID: 33929501
[TBL] [Abstract][Full Text] [Related]
6. Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia.
Johnston G; Ramsey HE; Liu Q; Wang J; Stengel KR; Sampathi S; Acharya P; Arrate M; Stubbs MC; Burn T; Savona MR; Hiebert SW
Gene; 2020 Aug; 752():144758. PubMed ID: 32422235
[TBL] [Abstract][Full Text] [Related]
7. HMG20B stabilizes association of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block.
Maiques-Diaz A; Nicosia L; Basma NJ; Romero-Camarero I; Camera F; Spencer GJ; Amaral FMR; Simeoni F; Wingelhofer B; Williamson AJK; Pierce A; Whetton AD; Somervaille TCP
Oncogene; 2022 Oct; 41(44):4841-4854. PubMed ID: 36171271
[TBL] [Abstract][Full Text] [Related]
8. LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML.
Barth J; Abou-El-Ardat K; Dalic D; Kurrle N; Maier AM; Mohr S; Schütte J; Vassen L; Greve G; Schulz-Fincke J; Schmitt M; Tosic M; Metzger E; Bug G; Khandanpour C; Wagner SA; Lübbert M; Jung M; Serve H; Schüle R; Berg T
Leukemia; 2019 Jun; 33(6):1411-1426. PubMed ID: 30679800
[TBL] [Abstract][Full Text] [Related]
9. Lsd1 as a therapeutic target in Gfi1-activated medulloblastoma.
Lee C; Rudneva VA; Erkek S; Zapatka M; Chau LQ; Tacheva-Grigorova SK; Garancher A; Rusert JM; Aksoy O; Lea R; Mohammad HP; Wang J; Weiss WA; Grimes HL; Pfister SM; Northcott PA; Wechsler-Reya RJ
Nat Commun; 2019 Jan; 10(1):332. PubMed ID: 30659187
[TBL] [Abstract][Full Text] [Related]
10. Histone demethylase LSD1-mediated repression of GATA-2 is critical for erythroid differentiation.
Guo Y; Fu X; Jin Y; Sun J; Liu Y; Huo B; Li X; Hu X
Drug Des Devel Ther; 2015; 9():3153-62. PubMed ID: 26124638
[TBL] [Abstract][Full Text] [Related]
11. Severe Inflammatory Reactions in Mice Expressing a GFI1
Fraszczak J; Arman KM; Lacroix M; Vadnais C; Gaboury L; Möröy T
J Immunol; 2021 Sep; 207(6):1599-1615. PubMed ID: 34408010
[TBL] [Abstract][Full Text] [Related]
12. GFI1 functions in transcriptional control and cell fate determination require SNAG domain methylation to recruit LSD1.
Velinder M; Singer J; Bareyan D; Meznarich J; Tracy CM; Fulcher JM; McClellan D; Lucente H; Franklin S; Sharma S; Engel ME
Biochem J; 2016 Oct; 473(19):3355-69. PubMed ID: 27480105
[TBL] [Abstract][Full Text] [Related]
13. GATA-1 Inhibits PU.1 Gene via DNA and Histone H3K9 Methylation of Its Distal Enhancer in Erythroleukemia.
Burda P; Vargova J; Curik N; Salek C; Papadopoulos GL; Strouboulis J; Stopka T
PLoS One; 2016; 11(3):e0152234. PubMed ID: 27010793
[TBL] [Abstract][Full Text] [Related]
14. Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation.
Ravasio R; Ceccacci E; Nicosia L; Hosseini A; Rossi PL; Barozzi I; Fornasari L; Zuffo RD; Valente S; Fioravanti R; Mercurio C; Varasi M; Mattevi A; Mai A; Pavesi G; Bonaldi T; Minucci S
Sci Adv; 2020 Apr; 6(15):eaax2746. PubMed ID: 32284990
[TBL] [Abstract][Full Text] [Related]
15. Differential transcriptional regulation of meis1 by Gfi1b and its co-factors LSD1 and CoREST.
Chowdhury AH; Ramroop JR; Upadhyay G; Sengupta A; Andrzejczyk A; Saleque S
PLoS One; 2013; 8(1):e53666. PubMed ID: 23308270
[TBL] [Abstract][Full Text] [Related]
16. EZH2 or HDAC1 Inhibition Reverses Multiple Myeloma-Induced Epigenetic Suppression of Osteoblast Differentiation.
Adamik J; Jin S; Sun Q; Zhang P; Weiss KR; Anderson JL; Silbermann R; Roodman GD; Galson DL
Mol Cancer Res; 2017 Apr; 15(4):405-417. PubMed ID: 28119431
[TBL] [Abstract][Full Text] [Related]
17. GFI1 Cooperates with IKZF1/IKAROS to Activate Gene Expression in T-cell Acute Lymphoblastic Leukemia.
Sun W; Guo J; McClellan D; Poeschla A; Bareyan D; Casey MJ; Cairns BR; Tantin D; Engel ME
Mol Cancer Res; 2022 Apr; 20(4):501-514. PubMed ID: 34980595
[TBL] [Abstract][Full Text] [Related]
18. The histone demethylase Lsd1 regulates multiple repressive gene programs during T cell development.
Stamos DB; Clubb LM; Mitra A; Chopp LB; Nie J; Ding Y; Das A; Venkataganesh H; Lee J; El-Khoury D; Li L; Bhandoola A; Bosselut R; Love PE
J Exp Med; 2021 Dec; 218(12):. PubMed ID: 34726730
[TBL] [Abstract][Full Text] [Related]
19. SUMOylation Regulates Growth Factor Independence 1 in Transcriptional Control and Hematopoiesis.
Andrade D; Velinder M; Singer J; Maese L; Bareyan D; Nguyen H; Chandrasekharan MB; Lucente H; McClellan D; Jones D; Sharma S; Liu F; Engel ME
Mol Cell Biol; 2016 May; 36(10):1438-50. PubMed ID: 26951200
[TBL] [Abstract][Full Text] [Related]
20. Superior efficacy of co-targeting GFI1/KDM1A and BRD4 against AML and post-MPN secondary AML cells.
Fiskus W; Mill CP; Nabet B; Perera D; Birdwell C; Manshouri T; Lara B; Kadia TM; DiNardo C; Takahashi K; Daver N; Bose P; Masarova L; Pemmaraju N; Kornblau S; Borthakur G; Montalban-Bravo G; Manero GG; Sharma S; Stubbs M; Su X; Green MR; Coarfa C; Verstovsek S; Khoury JD; Vakoc CR; Bhalla KN
Blood Cancer J; 2021 May; 11(5):98. PubMed ID: 34016956
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]