BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

641 related articles for article (PubMed ID: 31677858)

  • 41. Benzodioxole-Pyrazole Hybrids as Anti-Inflammatory and Analgesic Agents with COX-1,2/5-LOX Inhibition and Antioxidant Potential.
    Abd El Razik HA; Badr MH; Atta AH; Mouneir SM; Abu-Serie MM
    Arch Pharm (Weinheim); 2017 May; 350(5):. PubMed ID: 28418202
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Cyclic enaminone as new chemotype for selective cyclooxygenase-2 inhibitory, anti-inflammatory, and analgesic activities.
    Kumar R; Saha N; Purohit P; Garg SK; Seth K; Meena VS; Dubey S; Dave K; Goyal R; Sharma SS; Banerjee UC; Chakraborti AK
    Eur J Med Chem; 2019 Nov; 182():111601. PubMed ID: 31445233
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Synthesis of new multitarget-directed ligands containing thienopyrimidine nucleus for inhibition of 15-lipoxygenase, cyclooxygenases, and pro-inflammatory cytokines.
    Abdelkhalek AS; Kothayer H; Rezq S; Orabi KY; Romero DG; El-Sabbagh OI
    Eur J Med Chem; 2023 Aug; 256():115443. PubMed ID: 37182334
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Exploring new imines as anti-inflammatory COX and 5-LOX inhibitors with an improved pharmacokinetic profile.
    Said MF; Moussa BA; Mahrouse MA; Marie SM; Mohamed NM
    Future Med Chem; 2024 Feb; 16(4):311-334. PubMed ID: 38293746
    [No Abstract]   [Full Text] [Related]  

  • 45. Synthesis of new thiazolo-celecoxib analogues as dual cyclooxygenase-2/15-lipoxygenase inhibitors: Determination of regio-specific different pyrazole cyclization by 2D NMR.
    Abdelall EK; Kamel GM
    Eur J Med Chem; 2016 Aug; 118():250-8. PubMed ID: 27131067
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Synthesis of novel hybrids of pyrazole and coumarin as dual inhibitors of COX-2 and 5-LOX.
    Shen FQ; Wang ZC; Wu SY; Ren SZ; Man RJ; Wang BZ; Zhu HL
    Bioorg Med Chem Lett; 2017 Aug; 27(16):3653-3660. PubMed ID: 28720504
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor.
    Riendeau D; Percival MD; Boyce S; Brideau C; Charleson S; Cromlish W; Ethier D; Evans J; Falgueyret JP; Ford-Hutchinson AW; Gordon R; Greig G; Gresser M; Guay J; Kargman S; Léger S; Mancini JA; O'Neill G; Ouellet M; Rodger IW; Thérien M; Wang Z; Webb JK; Wong E; Chan CC
    Br J Pharmacol; 1997 May; 121(1):105-17. PubMed ID: 9146894
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Design, Synthesis, and Activity Evaluation of Stereoconfigured Tartarate Derivatives as Potential Anti-inflammatory Agents
    Kumari P; Singh P; Kaur J; Bhatti R
    J Med Chem; 2021 Jul; 64(13):9550-9566. PubMed ID: 34137625
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Design, synthesis, evaluation and molecular modelling studies of some novel 5,6-diphenyl-1,2,4-triazin-3(2H)-ones bearing five-member heterocyclic moieties as potential COX-2 inhibitors: A hybrid pharmacophore approach.
    Banerjee AG; Das N; Shengule SA; Sharma PA; Srivastava RS; Shrivastava SK
    Bioorg Chem; 2016 Dec; 69():102-120. PubMed ID: 27750057
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Non-acidic 1,3,4-trisubstituted-pyrazole derivatives as lonazolac analogs with promising COX-2 selectivity, anti-inflammatory activity and gastric safety profile.
    Abdellatif KRA; Fadaly WAA; Elshaier YAMM; Ali WAM; Kamel GM
    Bioorg Chem; 2018 Apr; 77():568-578. PubMed ID: 29475165
    [TBL] [Abstract][Full Text] [Related]  

  • 51. 1,4-Dihydroquinazolin-3(2H)-yl benzamide derivatives as anti-inflammatory and analgesic agents with an improved gastric profile: Design, synthesis, COX-1/2 inhibitory activity and molecular docking study.
    Sakr A; Kothayer H; Ibrahim SM; Baraka MM; Rezq S
    Bioorg Chem; 2019 Mar; 84():76-86. PubMed ID: 30481648
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Synthesis, biological evaluation and docking analysis of 3-methyl-1-phenylchromeno[4,3-c]pyrazol-4(1H)-ones as potential cyclooxygenase-2 (COX-2) inhibitors.
    Grover J; Kumar V; Sobhia ME; Jachak SM
    Bioorg Med Chem Lett; 2014 Oct; 24(19):4638-4642. PubMed ID: 25219899
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Design, synthesis and biological evaluation of benzo[1.3.2]dithiazolium ylide 1,1-dioxide derivatives as potential dual cyclooxygenase-2/5-lipoxygenase inhibitors.
    Tan CM; Chen GS; Chen CS; Chang PT; Chern JW
    Bioorg Med Chem; 2011 Nov; 19(21):6316-28. PubMed ID: 21958737
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Optimization of pyrazole-based compounds with 1,2,4-triazole-3-thiol moiety as selective COX-2 inhibitors cardioprotective drug candidates: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory, ulcerogenicity, cardiovascular evaluation, and molecular modeling studies.
    Abdellatif KRA; Abdelall EKA; Elshemy HAH; Philoppes JN; Hassanein EHM; Kahk NM
    Bioorg Chem; 2021 Sep; 114():105122. PubMed ID: 34243075
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Synthesis and biological evaluation of isoxazolo[4,5-d]pyridazin-4-(5H)-one analogues as potent anti-inflammatory agents.
    Özadalı K; Özkanlı F; Jain S; Rao PP; Velázquez-Martínez CA
    Bioorg Med Chem; 2012 May; 20(9):2912-22. PubMed ID: 22475926
    [TBL] [Abstract][Full Text] [Related]  

  • 56. New Substituted 5-Benzylideno-2-Adamantylthiazol[3,2-b][1,2,4]Triazol-6(5
    Tratrat C; Haroun M; Paparisva A; Kamoutsis C; Petrou A; Gavalas A; Eleftheriou P; Geronikaki A; Venugopala KN; Kochkar H; Nair AB
    Molecules; 2021 Jan; 26(3):. PubMed ID: 33513963
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Aryl/heteroaryl Substituted Celecoxib Derivatives as COX-2 Inhibitors: Synthesis, Anti-inflammatory Activity and Molecular Docking Studies.
    Madhava G; Ramana KV; Sudhana SM; Rao DS; Kumar KH; Lokanatha V; Rani AU; Raju CN
    Med Chem; 2017; 13(5):484-497. PubMed ID: 28228088
    [TBL] [Abstract][Full Text] [Related]  

  • 58. New imidazolone derivatives comprising a benzoate or sulfonamide moiety as anti-inflammatory and antibacterial inhibitors: Design, synthesis, selective COX-2, DHFR and molecular-modeling study.
    Metwally NH; Mohamed MS
    Bioorg Chem; 2020 Jun; 99():103438. PubMed ID: 31796216
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Design, synthesis and evaluation of novel diaryl-1,5-diazoles derivatives bearing morpholine as potent dual COX-2/5-LOX inhibitors and antitumor agents.
    Li Z; Wang ZC; Li X; Abbas M; Wu SY; Ren SZ; Liu QX; Liu Y; Chen PW; Duan YT; Lv PC; Zhu HL
    Eur J Med Chem; 2019 May; 169():168-184. PubMed ID: 30877972
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Synthesis, docking simulation, biological evaluations and 3D-QSAR study of 5-Aryl-6-(4-methylsulfonyl)-3-(metylthio)-1,2,4-triazine as selective cyclooxygenase-2 inhibitors.
    Irannejad H; Kebriaieezadeh A; Zarghi A; Montazer-Sadegh F; Shafiee A; Assadieskandar A; Amini M
    Bioorg Med Chem; 2014 Jan; 22(2):865-73. PubMed ID: 24361187
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 33.