406 related articles for article (PubMed ID: 31679650)
1. Multivariate Genome-wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy.
Nath AP; Ritchie SC; Grinberg NF; Tang HH; Huang QQ; Teo SM; Ahola-Olli AV; Würtz P; Havulinna AS; Santalahti K; Pitkänen N; Lehtimäki T; Kähönen M; Lyytikäinen LP; Raitoharju E; Seppälä I; Sarin AP; Ripatti S; Palotie A; Perola M; Viikari JS; Jalkanen S; Maksimow M; Salmi M; Wallace C; Raitakari OT; Salomaa V; Abraham G; Kettunen J; Inouye M
Am J Hum Genet; 2019 Dec; 105(6):1076-1090. PubMed ID: 31679650
[TBL] [Abstract][Full Text] [Related]
2. Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network.
Richard AC; Peters JE; Lee JC; Vahedi G; Schäffer AA; Siegel RM; Lyons PA; Smith KG
Genome Med; 2016 Jul; 8(1):76. PubMed ID: 27435189
[TBL] [Abstract][Full Text] [Related]
3. Genetic colocalization atlas points to common regulatory sites and genes for hematopoietic traits and hematopoietic contributions to disease phenotypes.
Thom CS; Voight BF
BMC Med Genomics; 2020 Jun; 13(1):89. PubMed ID: 32600345
[TBL] [Abstract][Full Text] [Related]
4. PLEIO: a method to map and interpret pleiotropic loci with GWAS summary statistics.
Lee CH; Shi H; Pasaniuc B; Eskin E; Han B
Am J Hum Genet; 2021 Jan; 108(1):36-48. PubMed ID: 33352115
[TBL] [Abstract][Full Text] [Related]
5. A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects.
Shameer K; Denny JC; Ding K; Jouni H; Crosslin DR; de Andrade M; Chute CG; Peissig P; Pacheco JA; Li R; Bastarache L; Kho AN; Ritchie MD; Masys DR; Chisholm RL; Larson EB; McCarty CA; Roden DM; Jarvik GP; Kullo IJ
Hum Genet; 2014 Jan; 133(1):95-109. PubMed ID: 24026423
[TBL] [Abstract][Full Text] [Related]
6. Testing Genetic Pleiotropy with GWAS Summary Statistics for Marginal and Conditional Analyses.
Deng Y; Pan W
Genetics; 2017 Dec; 207(4):1285-1299. PubMed ID: 28971959
[TBL] [Abstract][Full Text] [Related]
7. Integrating disease and drug-related phenotypes for improved identification of pharmacogenomic variants.
Ouellette TW; Wright GE; Drögemöller BI; Ross CJ; Carleton BC
Pharmacogenomics; 2021 Apr; 22(5):251-261. PubMed ID: 33769074
[TBL] [Abstract][Full Text] [Related]
8. A methodology for multivariate phenotype-based genome-wide association studies to mine pleiotropic genes.
Park SH; Lee JY; Kim S
BMC Syst Biol; 2011; 5 Suppl 2(Suppl 2):S13. PubMed ID: 22784570
[TBL] [Abstract][Full Text] [Related]
9. Shared genetic underpinnings of childhood obesity and adult cardiometabolic diseases.
Tekola-Ayele F; Lee A; Workalemahu T; Sánchez-Pozos K
Hum Genomics; 2019 Apr; 13(1):17. PubMed ID: 30947744
[TBL] [Abstract][Full Text] [Related]
10. Biological basis of extensive pleiotropy between blood traits and cancer risk.
Pardo-Cea MA; Farré X; Esteve A; Palade J; Espín R; Mateo F; Alsop E; Alorda M; Blay N; Baiges A; Shabbir A; Comellas F; Gómez A; Arnan M; Teulé A; Salinas M; Berrocal L; Brunet J; Rofes P; Lázaro C; Conesa M; Rojas JJ; Velten L; Fendler W; Smyczynska U; Chowdhury D; Zeng Y; He HH; Li R; Van Keuren-Jensen K; de Cid R; Pujana MA
Genome Med; 2024 Feb; 16(1):21. PubMed ID: 38308367
[TBL] [Abstract][Full Text] [Related]
11. Multi-trait association studies discover pleiotropic loci between Alzheimer's disease and cardiometabolic traits.
Bone WP; Siewert KM; Jha A; Klarin D; Damrauer SM; ; Chang KM; Tsao PS; Assimes TL; Ritchie MD; Voight BF
Alzheimers Res Ther; 2021 Feb; 13(1):34. PubMed ID: 33541420
[TBL] [Abstract][Full Text] [Related]
12. Genome-wide analyses of multiple obesity-related cytokines and hormones informs biology of cardiometabolic traits.
Meeks KAC; Bentley AR; Gouveia MH; Chen G; Zhou J; Lei L; Adeyemo AA; Doumatey AP; Rotimi CN
Genome Med; 2021 Oct; 13(1):156. PubMed ID: 34620218
[TBL] [Abstract][Full Text] [Related]
13. Pleiotropy informed adaptive association test of multiple traits using genome-wide association study summary data.
Masotti M; Guo B; Wu B
Biometrics; 2019 Dec; 75(4):1076-1085. PubMed ID: 31021400
[TBL] [Abstract][Full Text] [Related]
14. Investigation of multi-trait associations using pathway-based analysis of GWAS summary statistics.
Pei G; Sun H; Dai Y; Liu X; Zhao Z; Jia P
BMC Genomics; 2019 Feb; 20(Suppl 1):79. PubMed ID: 30712509
[TBL] [Abstract][Full Text] [Related]
15. Identification of novel variants associated with osteoporosis, type 2 diabetes and potentially pleiotropic loci using pleiotropic cFDR method.
Hu Y; Tan LJ; Chen XD; Greenbaum J; Deng HW
Bone; 2018 Dec; 117():6-14. PubMed ID: 30172742
[TBL] [Abstract][Full Text] [Related]
16. Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein.
Ligthart S; de Vries PS; Uitterlinden AG; Hofman A; ; Franco OH; Chasman DI; Dehghan A
PLoS One; 2015; 10(3):e0118859. PubMed ID: 25768928
[TBL] [Abstract][Full Text] [Related]
17. Distinguishing pleiotropy from linked QTL between milk production traits and mastitis resistance in Nordic Holstein cattle.
Cai Z; Dusza M; Guldbrandtsen B; Lund MS; Sahana G
Genet Sel Evol; 2020 Apr; 52(1):19. PubMed ID: 32264818
[TBL] [Abstract][Full Text] [Related]
18. Genome-wide identification of circulating-miRNA expression quantitative trait loci reveals the role of several miRNAs in the regulation of cardiometabolic phenotypes.
Nikpay M; Beehler K; Valsesia A; Hager J; Harper ME; Dent R; McPherson R
Cardiovasc Res; 2019 Sep; 115(11):1629-1645. PubMed ID: 30715214
[TBL] [Abstract][Full Text] [Related]
19. The impact of cell type and context-dependent regulatory variants on human immune traits.
Mu Z; Wei W; Fair B; Miao J; Zhu P; Li YI
Genome Biol; 2021 Apr; 22(1):122. PubMed ID: 33926512
[TBL] [Abstract][Full Text] [Related]
20. Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network.
Pendergrass SA; Brown-Gentry K; Dudek S; Frase A; Torstenson ES; Goodloe R; Ambite JL; Avery CL; Buyske S; Bůžková P; Deelman E; Fesinmeyer MD; Haiman CA; Heiss G; Hindorff LA; Hsu CN; Jackson RD; Kooperberg C; Le Marchand L; Lin Y; Matise TC; Monroe KR; Moreland L; Park SL; Reiner A; Wallace R; Wilkens LR; Crawford DC; Ritchie MD
PLoS Genet; 2013; 9(1):e1003087. PubMed ID: 23382687
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]