BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 31693218)

  • 1. Aza-CGP37157-lipoic hybrids designed as novel Nrf2-inducers and antioxidants exert neuroprotection against oxidative stress and show neuroinflammation inhibitory properties.
    Michalska P; Tenti G; Satriani M; Cores A; Ramos MT; García AG; Menéndez JC; León R
    Drug Dev Res; 2020 May; 81(3):283-294. PubMed ID: 31693218
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia.
    Buendia I; Tenti G; Michalska P; Méndez-López I; Luengo E; Satriani M; Padín-Nogueira F; López MG; Ramos MT; García AG; Menéndez JC; León R
    ACS Chem Neurosci; 2017 Jan; 8(1):67-81. PubMed ID: 27731633
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enantioselective Synthesis and Pharmacological Evaluation of Aza-CGP37157-Lipoic Acid Hybrids for the Treatment of Alzheimer's Disease.
    Cores Á; Michalska P; Pérez JM; Crisman E; Gómez C; Villacampa M; Menéndez JC; León R
    Antioxidants (Basel); 2022 Jan; 11(1):. PubMed ID: 35052616
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New melatonin-cinnamate hybrids as multi-target drugs for neurodegenerative diseases: Nrf2-induction, antioxidant effect and neuroprotection.
    Buendia I; Navarro E; Michalska P; Gameiro I; Egea J; Abril S; López A; González-Lafuente L; López MG; León R
    Future Med Chem; 2015; 7(15):1961-9. PubMed ID: 26496465
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alpha lipoic acid exerts antioxidant effect via Nrf2/HO-1 pathway activation and suppresses hepatic stellate cells activation induced by methotrexate in rats.
    Fayez AM; Zakaria S; Moustafa D
    Biomed Pharmacother; 2018 Sep; 105():428-433. PubMed ID: 29879626
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Benzothiazepine CGP37157 and its isosteric 2'-methyl analogue provide neuroprotection and block cell calcium entry.
    González-Lafuente L; Egea J; León R; Martínez-Sanz FJ; Monjas L; Perez C; Merino C; García-De Diego AM; Rodríguez-Franco MI; García AG; Villarroya M; López MG; de Los Ríos C
    ACS Chem Neurosci; 2012 Jul; 3(7):519-29. PubMed ID: 22860221
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of new ferulic/lipoic/comenic acid-melatonin hybrids as antioxidants and Nrf2 activators via Ugi reaction.
    Pachón-Angona I; Martin H; Chhor S; Oset-Gasque MJ; Refouvelet B; Marco-Contelles J; Ismaili L
    Future Med Chem; 2019 Dec; 11(24):3097-3108. PubMed ID: 31838896
    [No Abstract]   [Full Text] [Related]  

  • 8. α-Lipoic Acid Promotes Neurological Recovery After Ischemic Stroke by Activating the Nrf2/HO-1 Pathway to Attenuate Oxidative Damage.
    Lv C; Maharjan S; Wang Q; Sun Y; Han X; Wang S; Mao Z; Xin Y; Zhang B
    Cell Physiol Biochem; 2017; 43(3):1273-1287. PubMed ID: 28992629
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neuroprotective profile of pyridothiazepines with blocking activity of the mitochondrial Na(+)/Ca(2+) exchanger.
    Martínez-Sanz FJ; Lajarín-Cuesta R; González-Lafuente L; Moreno-Ortega AJ; Punzón E; Cano-Abad MF; de los Ríos C
    Eur J Med Chem; 2016 Feb; 109():114-23. PubMed ID: 26774037
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lipoic acid and pentoxifylline mitigate nandrolone decanoate-induced neurobehavioral perturbations in rats via re-balance of brain neurotransmitters, up-regulation of Nrf2/HO-1 pathway, and down-regulation of TNFR1 expression.
    Ahmed MA; El-Awdan SA
    Horm Behav; 2015 Jul; 73():186-99. PubMed ID: 26187709
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A co-drug conjugate of naringenin and lipoic acid mediates neuroprotection in a rat model of oxidative stress.
    Saleh TM; Saleh MC; Connell BJ; Song YH
    Clin Exp Pharmacol Physiol; 2017 Oct; 44(10):1008-1016. PubMed ID: 28636787
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protective effect of lipoic acid against oxidative stress is mediated by Keap1/Nrf2-dependent heme oxygenase-1 induction in the RGC-5 cellline.
    Koriyama Y; Nakayama Y; Matsugo S; Kato S
    Brain Res; 2013 Mar; 1499():145-57. PubMed ID: 23295186
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lipoamide Ameliorates Oxidative Stress via Induction of Nrf2/ARE Signaling Pathway in PC12 Cells.
    Hou Y; Li X; Peng S; Yao J; Bai F; Fang J
    J Agric Food Chem; 2019 Jul; 67(29):8227-8234. PubMed ID: 31299148
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification and optimization of piperlongumine analogues as potential antioxidant and anti-inflammatory agents via activation of Nrf2.
    Ji L; Qu L; Wang C; Peng W; Li S; Yang H; Luo H; Yin F; Lu D; Liu X; Kong L; Wang X
    Eur J Med Chem; 2021 Jan; 210():112965. PubMed ID: 33148493
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Carvacryl acetate, a semisynthetic monoterpenic ester obtained from essential oils, provides neuroprotection against cerebral ischemia reperfusion-induced oxidative stress injury via the Nrf2 signalling pathway.
    Song Y; Wang LB; Bei Y; Qin DX; Ai LY; Ma QZ; Lin PY
    Food Funct; 2020 Feb; 11(2):1754-1763. PubMed ID: 32043502
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Essential role of Nrf2 in the protective effect of lipoic acid against lipoapoptosis in hepatocytes.
    Pilar Valdecantos M; Prieto-Hontoria PL; Pardo V; Módol T; Santamaría B; Weber M; Herrero L; Serra D; Muntané J; Cuadrado A; Moreno-Aliaga MJ; Alfredo Martínez J; Valverde ÁM
    Free Radic Biol Med; 2015 Jul; 84():263-278. PubMed ID: 25841776
    [TBL] [Abstract][Full Text] [Related]  

  • 17. α-Lipoic acid protects against microcystin-LR induced hepatotoxicity through regeneration of glutathione via activation of Nrf2.
    Gu L; Li S; Bai J; Zhang Q; Han Z
    Environ Toxicol; 2020 Jul; 35(7):738-746. PubMed ID: 32061150
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vitro neuroprotection against oxidative stress by pre-treatment with a combination of dihydrolipoic acid and phenyl-butyl nitrones.
    Koenig ML; Meyerhoff JL
    Neurotox Res; 2003; 5(4):265-72. PubMed ID: 12835118
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of neuroprotective Agents: Potent, brain Penetrating, lipoic acid derivatives for the potential treatment of ischemic stroke by regulating oxidative stress and inflammation - a Preliminary study.
    Zhu C; Wang Y; Li Y; Wang T; Ye F; Su W; Chen T; Zhang C; Xiong L
    Bioorg Chem; 2024 Jun; 147():107339. PubMed ID: 38643566
    [TBL] [Abstract][Full Text] [Related]  

  • 20. N-acetylcysteine and alpha-lipoic acid improve antioxidant defenses and decrease oxidative stress, inflammation and serum lipid levels in ovariectomized rats via estrogen-independent mechanisms.
    Delgobo M; Agnes JP; Gonçalves RM; Dos Santos VW; Parisotto EB; Zamoner A; Zanotto-Filho A
    J Nutr Biochem; 2019 May; 67():190-200. PubMed ID: 30951973
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.