These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 31695028)

  • 21. Application of human FcRn transgenic mice as a pharmacokinetic screening tool of monoclonal antibody.
    Haraya K; Tachibana T; Nanami M; Ishigai M
    Xenobiotica; 2014 Dec; 44(12):1127-34. PubMed ID: 25030041
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Fusion of a short peptide that binds immunoglobulin G to a recombinant protein substantially increases its plasma half-life in mice.
    Sockolosky JT; Kivimäe S; Szoka FC
    PLoS One; 2014; 9(7):e102566. PubMed ID: 25057984
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn
    Mester S; Evers M; Meyer S; Nilsen J; Greiff V; Sandlie I; Leusen J; Andersen JT
    MAbs; 2021; 13(1):1893888. PubMed ID: 33691596
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Cellular recycling-driven in vivo half-life extension using recombinant albumin fusions tuned for neonatal Fc receptor (FcRn) engagement.
    Larsen MT; Rawsthorne H; Schelde KK; Dagnæs-Hansen F; Cameron J; Howard KA
    J Control Release; 2018 Oct; 287():132-141. PubMed ID: 30016735
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Engineering human IgG1 affinity to human neonatal Fc receptor: impact of affinity improvement on pharmacokinetics in primates.
    Yeung YA; Leabman MK; Marvin JS; Qiu J; Adams CW; Lien S; Starovasnik MA; Lowman HB
    J Immunol; 2009 Jun; 182(12):7663-71. PubMed ID: 19494290
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Identification of human IgG1 variant with enhanced FcRn binding and without increased binding to rheumatoid factor autoantibody.
    Maeda A; Iwayanagi Y; Haraya K; Tachibana T; Nakamura G; Nambu T; Esaki K; Hattori K; Igawa T
    MAbs; 2017 Jul; 9(5):844-853. PubMed ID: 28387635
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Cross-species binding analyses of mouse and human neonatal Fc receptor show dramatic differences in immunoglobulin G and albumin binding.
    Andersen JT; Daba MB; Berntzen G; Michaelsen TE; Sandlie I
    J Biol Chem; 2010 Feb; 285(7):4826-36. PubMed ID: 20018855
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Fc Engineering of Human IgG1 for Altered Binding to the Neonatal Fc Receptor Affects Fc Effector Functions.
    Grevys A; Bern M; Foss S; Bratlie DB; Moen A; Gunnarsen KS; Aase A; Michaelsen TE; Sandlie I; Andersen JT
    J Immunol; 2015 Jun; 194(11):5497-508. PubMed ID: 25904551
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Engineering a monomeric Fc domain modality by N-glycosylation for the half-life extension of biotherapeutics.
    Ishino T; Wang M; Mosyak L; Tam A; Duan W; Svenson K; Joyce A; O'Hara DM; Lin L; Somers WS; Kriz R
    J Biol Chem; 2013 Jun; 288(23):16529-16537. PubMed ID: 23615911
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A novel approach to investigate the effect of methionine oxidation on pharmacokinetic properties of therapeutic antibodies.
    Stracke J; Emrich T; Rueger P; Schlothauer T; Kling L; Knaupp A; Hertenberger H; Wolfert A; Spick C; Lau W; Drabner G; Reiff U; Koll H; Papadimitriou A
    MAbs; 2014; 6(5):1229-42. PubMed ID: 25517308
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Quantitative Analysis of Human Neonatal Fc Receptor (FcRn) Tissue Expression in Transgenic Mice by Online Peptide Immuno-Affinity LC-HRMS.
    Fan YY; Neubert H
    Anal Chem; 2016 Apr; 88(8):4239-47. PubMed ID: 27012525
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Engineered soluble monomeric IgG1 CH3 domain: generation, mechanisms of function, and implications for design of biological therapeutics.
    Ying T; Chen W; Feng Y; Wang Y; Gong R; Dimitrov DS
    J Biol Chem; 2013 Aug; 288(35):25154-25164. PubMed ID: 23867459
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A new class of recombinant human albumin with multiple surface thiols exhibits stable conjugation and enhanced FcRn binding and blood circulation.
    Schelde KK; Nicholls K; Dagnæs-Hansen F; Bunting K; Rawsthorne H; Andersen B; Finnis CJA; Williamson M; Cameron J; Howard KA
    J Biol Chem; 2019 Mar; 294(10):3735-3743. PubMed ID: 30602565
    [TBL] [Abstract][Full Text] [Related]  

  • 34. pH-dependent binding engineering reveals an FcRn affinity threshold that governs IgG recycling.
    Borrok MJ; Wu Y; Beyaz N; Yu XQ; Oganesyan V; Dall'Acqua WF; Tsui P
    J Biol Chem; 2015 Feb; 290(7):4282-90. PubMed ID: 25538249
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Pharmacokinetics of novel Fc-engineered monoclonal and multispecific antibodies in cynomolgus monkeys and humanized FcRn transgenic mouse models.
    Valente D; Mauriac C; Schmidt T; Focken I; Beninga J; Mackness B; Qiu H; Vicat P; Kandira A; Radošević K; Rao S; Darbyshire J; Kabiri M
    MAbs; 2020; 12(1):1829337. PubMed ID: 33079615
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Utility of a human FcRn transgenic mouse model in drug discovery for early assessment and prediction of human pharmacokinetics of monoclonal antibodies.
    Avery LB; Wang M; Kavosi MS; Joyce A; Kurz JC; Fan YY; Dowty ME; Zhang M; Zhang Y; Cheng A; Hua F; Jones HM; Neubert H; Polzer RJ; O'Hara DM
    MAbs; 2016; 8(6):1064-78. PubMed ID: 27232760
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A strategy for bacterial production of a soluble functional human neonatal Fc receptor.
    Andersen JT; Justesen S; Berntzen G; Michaelsen TE; Lauvrak V; Fleckenstein B; Buus S; Sandlie I
    J Immunol Methods; 2008 Feb; 331(1-2):39-49. PubMed ID: 18155020
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Neonatal Fc receptor (FcRn): a novel target for therapeutic antibodies and antibody engineering.
    Wang Y; Tian Z; Thirumalai D; Zhang X
    J Drug Target; 2014 May; 22(4):269-78. PubMed ID: 24404896
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Enhancement of antibody-dependent cell-mediated cytotoxicity by endowing IgG with FcαRI (CD89) binding.
    Borrok MJ; Luheshi NM; Beyaz N; Davies GC; Legg JW; Wu H; Dall'Acqua WF; Tsui P
    MAbs; 2015; 7(4):743-51. PubMed ID: 25970007
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding.
    Andersen JT; Dalhus B; Viuff D; Ravn BT; Gunnarsen KS; Plumridge A; Bunting K; Antunes F; Williamson R; Athwal S; Allan E; Evans L; Bjørås M; Kjærulff S; Sleep D; Sandlie I; Cameron J
    J Biol Chem; 2014 May; 289(19):13492-502. PubMed ID: 24652290
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.