301 related articles for article (PubMed ID: 31696233)
1. Cerebellar contribution to the cognitive alterations in SCA1: evidence from mouse models.
Asher M; Rosa JG; Rainwater O; Duvick L; Bennyworth M; Lai RY; ; Kuo SH; Cvetanovic M
Hum Mol Genet; 2020 Jan; 29(1):117-131. PubMed ID: 31696233
[TBL] [Abstract][Full Text] [Related]
2. BDNF is altered in a brain-region specific manner and rescues deficits in Spinocerebellar Ataxia Type 1.
Rosa JG; Hamel K; Soles A; Sheeler C; Borgenheimer E; Gilliat S; Sbrocco K; Ghanoum F; Handler HP; Forster C; Rainwater O; Cvetanovic M
Neurobiol Dis; 2023 Mar; 178():106023. PubMed ID: 36724861
[TBL] [Abstract][Full Text] [Related]
3. Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles.
Handler HP; Duvick L; Mitchell JS; Cvetanovic M; Reighard M; Soles A; Mather KB; Rainwater O; Serres S; Nichols-Meade T; Coffin SL; You Y; Ruis BL; O'Callaghan B; Henzler C; Zoghbi HY; Orr HT
Neuron; 2023 Feb; 111(4):493-507.e6. PubMed ID: 36577403
[TBL] [Abstract][Full Text] [Related]
4. Indirect Negative Effect of Mutant Ataxin-1 on Short- and Long-Term Synaptic Plasticity in Mouse Models of Spinocerebellar Ataxia Type 1.
Shuvaev AN; Belozor OS; Mozhei OI; Shuvaev AN; Fritsler YV; Khilazheva ED; Mosyagina AI; Hirai H; Teschemacher AG; Kasparov S
Cells; 2022 Jul; 11(14):. PubMed ID: 35883691
[TBL] [Abstract][Full Text] [Related]
5. Modulation of ATXN1 S776 phosphorylation reveals the importance of allele-specific targeting in SCA1.
Nitschke L; Coffin SL; Xhako E; El-Najjar DB; Orengo JP; Alcala E; Dai Y; Wan YW; Liu Z; Orr HT; Zoghbi HY
JCI Insight; 2021 Feb; 6(3):. PubMed ID: 33554954
[TBL] [Abstract][Full Text] [Related]
6. Mood alterations in mouse models of Spinocerebellar Ataxia type 1.
Asher M; Rosa JG; Cvetanovic M
Sci Rep; 2021 Jan; 11(1):713. PubMed ID: 33436887
[TBL] [Abstract][Full Text] [Related]
7. Ataxin-1 regulates the cerebellar bioenergetics proteome through the GSK3β-mTOR pathway which is altered in Spinocerebellar ataxia type 1 (SCA1).
Sánchez I; Balagué E; Matilla-Dueñas A
Hum Mol Genet; 2016 Sep; 25(18):4021-4040. PubMed ID: 27466200
[TBL] [Abstract][Full Text] [Related]
8. Ataxin-1 regulates proliferation of hippocampal neural precursors.
Asher M; Johnson A; Zecevic B; Pease D; Cvetanovic M
Neuroscience; 2016 May; 322():54-65. PubMed ID: 26876606
[TBL] [Abstract][Full Text] [Related]
9. The extra-cerebellar effects of spinocerebellar ataxia type 1 (SCA1): looking beyond the cerebellum.
Olmos V; Gogia N; Luttik K; Haidery F; Lim J
Cell Mol Life Sci; 2022 Jul; 79(8):404. PubMed ID: 35802260
[TBL] [Abstract][Full Text] [Related]
10. ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism.
Rousseaux MWC; Tschumperlin T; Lu HC; Lackey EP; Bondar VV; Wan YW; Tan Q; Adamski CJ; Friedrich J; Twaroski K; Chen W; Tolar J; Henzler C; Sharma A; Bajić A; Lin T; Duvick L; Liu Z; Sillitoe RV; Zoghbi HY; Orr HT
Neuron; 2018 Mar; 97(6):1235-1243.e5. PubMed ID: 29526553
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of colony-stimulating factor 1 receptor early in disease ameliorates motor deficits in SCA1 mice.
Qu W; Johnson A; Kim JH; Lukowicz A; Svedberg D; Cvetanovic M
J Neuroinflammation; 2017 May; 14(1):107. PubMed ID: 28545543
[TBL] [Abstract][Full Text] [Related]
12. Antisense oligonucleotide-mediated ataxin-1 reduction prolongs survival in SCA1 mice and reveals disease-associated transcriptome profiles.
Friedrich J; Kordasiewicz HB; O'Callaghan B; Handler HP; Wagener C; Duvick L; Swayze EE; Rainwater O; Hofstra B; Benneyworth M; Nichols-Meade T; Yang P; Chen Z; Ortiz JP; Clark HB; Öz G; Larson S; Zoghbi HY; Henzler C; Orr HT
JCI Insight; 2018 Nov; 3(21):. PubMed ID: 30385727
[TBL] [Abstract][Full Text] [Related]
13. Sphingolipid metabolism governs Purkinje cell patterned degeneration in
Blot FGC; Krijnen WHJJ; Den Hoedt S; Osório C; White JJ; Mulder MT; Schonewille M
Proc Natl Acad Sci U S A; 2021 Sep; 118(36):. PubMed ID: 34479994
[TBL] [Abstract][Full Text] [Related]
14. Cross-species genetic screens identify transglutaminase 5 as a regulator of polyglutamine-expanded ataxin-1.
Lee WS; Al-Ramahi I; Jeong HH; Jang Y; Lin T; Adamski CJ; Lavery LA; Rath S; Richman R; Bondar VV; Alcala E; Revelli JP; Orr HT; Liu Z; Botas J; Zoghbi HY
J Clin Invest; 2022 May; 132(9):. PubMed ID: 35499073
[TBL] [Abstract][Full Text] [Related]
15. Non-invasive detection of neurochemical changes prior to overt pathology in a mouse model of spinocerebellar ataxia type 1.
Emir UE; Brent Clark H; Vollmers ML; Eberly LE; Öz G
J Neurochem; 2013 Dec; 127(5):660-8. PubMed ID: 24032423
[TBL] [Abstract][Full Text] [Related]
16. Pre-ataxic loss of intrinsic plasticity and motor learning in a mouse model of SCA1.
Osório C; White JJ; Lu H; Beekhof GC; Fiocchi FR; Andriessen CA; Dijkhuizen S; Post L; Schonewille M
Brain; 2023 Jun; 146(6):2332-2345. PubMed ID: 36352508
[TBL] [Abstract][Full Text] [Related]
17. Mapping SCA1 regional vulnerabilities reveals neural and skeletal muscle contributions to disease.
Duvick L; Southern WM; Benzow KA; Burch ZN; Handler HP; Mitchell JS; Kuivinen H; Gadiparthi U; Yang P; Soles A; Sheeler CA; Rainwater O; Serres S; Lind EB; Nichols-Meade T; You Y; O'Callaghan B; Zoghbi HY; Cvetanovic M; Wheeler VC; Ervasti JM; Koob MD; Orr HT
JCI Insight; 2024 Mar; 9(9):. PubMed ID: 38512434
[TBL] [Abstract][Full Text] [Related]
18. Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis.
Crespo-Barreto J; Fryer JD; Shaw CA; Orr HT; Zoghbi HY
PLoS Genet; 2010 Jul; 6(7):e1001021. PubMed ID: 20628574
[TBL] [Abstract][Full Text] [Related]
19. Therapeutic Strategies for Spinocerebellar Ataxia Type 1.
Kerkhof LMC; van de Warrenburg BPC; van Roon-Mom WMC; Buijsen RAM
Biomolecules; 2023 May; 13(5):. PubMed ID: 37238658
[TBL] [Abstract][Full Text] [Related]
20. Cerebellar Transcriptome Profiles of ATXN1 Transgenic Mice Reveal SCA1 Disease Progression and Protection Pathways.
Ingram M; Wozniak EAL; Duvick L; Yang R; Bergmann P; Carson R; O'Callaghan B; Zoghbi HY; Henzler C; Orr HT
Neuron; 2016 Mar; 89(6):1194-1207. PubMed ID: 26948890
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]