BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 31696959)

  • 1. 1,2,4-Triazole-conjugated 1,3,4-thiadiazole hybrid scaffolds: A potent ameliorant of carrageenan-induced inflammation by lessening proinflammatory mediators.
    Pathak P; Shukla PK; Naumovich V; Grishina M; Verma A; Potemkin V
    Arch Pharm (Weinheim); 2020 Jan; 353(1):e1900233. PubMed ID: 31696959
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design and synthesis of quinazolinone derivatives as anti-inflammatory agents: pharmacophore modeling and 3D QSAR studies.
    Chaitanya P; Reddy GD; Varun G; Srikanth LM; Prasad VV; Ravindernath A
    Med Chem; 2014; 10(7):711-23. PubMed ID: 24286396
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Anti-inflammatory drug approach: Synthesis and biological evaluation of novel pyrazolo[3,4-d]pyrimidine compounds.
    Atatreh N; Youssef AM; Ghattas MA; Al Sorkhy M; Alrawashdeh S; Al-Harbi KB; El-Ashmawy IM; Almundarij TI; Abdelghani AA; Abd-El-Aziz AS
    Bioorg Chem; 2019 May; 86():393-400. PubMed ID: 30763886
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, biological evaluation and molecular modeling study of pyrazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents.
    Tewari AK; Singh VP; Yadav P; Gupta G; Singh A; Goel RK; Shinde P; Mohan CG
    Bioorg Chem; 2014 Oct; 56():8-15. PubMed ID: 24893208
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and synthesis of novel 4-fluorobenzamide-based derivatives as promising anti-inflammatory and analgesic agents with an enhanced gastric tolerability and COX-inhibitory activity.
    Halim PA; Georgey HH; George MY; El Kerdawy AM; Said MF
    Bioorg Chem; 2021 Oct; 115():105253. PubMed ID: 34390973
    [TBL] [Abstract][Full Text] [Related]  

  • 6. COX-1/COX-2 inhibition assays and histopathological study of the new designed anti-inflammatory agent with a pyrazolopyrimidine core.
    Abdelall EKA; Lamie PF; Ahmed AKM; El-Nahass ES
    Bioorg Chem; 2019 May; 86():235-253. PubMed ID: 30716621
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel 4-methylsulfonylphenyl derivatives as NSAIDS with preferential COX-2 inhibition.
    Amin NH; Mohammed AA; Abdellatif KR
    Future Med Chem; 2018 Jan; 10(1):53-70. PubMed ID: 29235887
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 1,3,4-Trisubstituted pyrazole analogues as promising anti-inflammatory agents.
    Alegaon SG; Alagawadi KR; Garg MK; Dushyant K; Vinod D
    Bioorg Chem; 2014 Jun; 54():51-9. PubMed ID: 24793214
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study.
    El-Miligy MMM; Hazzaa AA; El-Messmary H; Nassra RA; El-Hawash SAM
    Bioorg Chem; 2017 Jun; 72():102-115. PubMed ID: 28390993
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 2. 1,3,4- and 1,2,4-thiadiazole series.
    Song Y; Connor DT; Sercel AD; Sorenson RJ; Doubleday R; Unangst PC; Roth BD; Beylin VG; Gilbertsen RB; Chan K; Schrier DJ; Guglietta A; Bornemeier DA; Dyer RD
    J Med Chem; 1999 Apr; 42(7):1161-9. PubMed ID: 10197960
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 1-(4-Methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazole-3-carboxamides: synthesis, molecular modeling, evaluation of their anti-inflammatory activity and ulcerogenicity.
    Abdel-Aziz M; Beshr EA; Abdel-Rahman IM; Ozadali K; Tan OU; Aly OM
    Eur J Med Chem; 2014 Apr; 77():155-65. PubMed ID: 24631895
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Heterocycles 48. Synthesis, Characterization and Biological Evaluation of Imidazo[2,1-
    Cristina A; Leonte D; Vlase L; Bencze LC; Imre S; Marc G; Apan B; Mogoșan C; Zaharia V
    Molecules; 2018 Sep; 23(10):. PubMed ID: 30248903
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dual evaluation of some novel 2-amino-substituted coumarinylthiazoles as anti-inflammatory-antimicrobial agents and their docking studies with COX-1/COX-2 active sites.
    Chandak N; Kumar P; Kaushik P; Varshney P; Sharma C; Kaushik D; Jain S; Aneja KR; Sharma PK
    J Enzyme Inhib Med Chem; 2014 Aug; 29(4):476-84. PubMed ID: 23777557
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, characterization, evaluation and molecular dynamics studies of 5, 6-diphenyl-1,2,4-triazin-3(2H)-one derivatives bearing 5-substituted 1,3,4-oxadiazole as potential anti-inflammatory and analgesic agents.
    Banerjee AG; Das N; Shengule SA; Srivastava RS; Shrivastava SK
    Eur J Med Chem; 2015 Aug; 101():81-95. PubMed ID: 26117820
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, in vitro and in vivo biological evaluation, COX-1/2 inhibition and molecular docking study of indole-N-acylhydrazone derivatives.
    Moraes ADTO; Miranda MDS; Jacob ÍTT; Amorim CADC; Moura RO; Silva SÂSD; Soares MBP; Almeida SMV; Souza TRCL; Oliveira JF; Silva TGD; Melo CML; Moreira DRM; Lima MDCA
    Bioorg Med Chem; 2018 Nov; 26(20):5388-5396. PubMed ID: 30293795
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, anti-inflammatory, analgesic and COX-1/2 inhibition activities of anilides based on 5,5-diphenylimidazolidine-2,4-dione scaffold: Molecular docking studies.
    Abdel-Aziz AA; El-Azab AS; Abou-Zeid LA; ElTahir KE; Abdel-Aziz NI; Ayyad RR; Al-Obaid AM
    Eur J Med Chem; 2016 Jun; 115():121-31. PubMed ID: 26999325
    [TBL] [Abstract][Full Text] [Related]  

  • 17. New indomethacin analogs as selective COX-2 inhibitors: Synthesis, COX-1/2 inhibitory activity, anti-inflammatory, ulcerogenicity, histopathological, and docking studies.
    Abdellatif KRA; Abdelall EKA; Elshemy HAH; El-Nahass ES; Abdel-Fattah MM; Abdelgawad YYM
    Arch Pharm (Weinheim); 2021 Apr; 354(4):e2000328. PubMed ID: 33314237
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design of 5-(3,5-di-tert-butyl-4-hydroxyphenyl)-1,3,4-thiadiazoles, -1,3,4-oxadiazoles, and -1,2,4-triazoles as orally-active, nonulcerogenic antiinflammatory agents.
    Mullican MD; Wilson MW; Connor DT; Kostlan CR; Schrier DJ; Dyer RD
    J Med Chem; 1993 Apr; 36(8):1090-9. PubMed ID: 8478906
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New Substituted 5-Benzylideno-2-Adamantylthiazol[3,2-b][1,2,4]Triazol-6(5
    Tratrat C; Haroun M; Paparisva A; Kamoutsis C; Petrou A; Gavalas A; Eleftheriou P; Geronikaki A; Venugopala KN; Kochkar H; Nair AB
    Molecules; 2021 Jan; 26(3):. PubMed ID: 33513963
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel 1,3,4-oxadiazole/oxime hybrids: Synthesis, docking studies and investigation of anti-inflammatory, ulcerogenic liability and analgesic activities.
    Abd-Ellah HS; Abdel-Aziz M; Shoman ME; Beshr EA; Kaoud TS; Ahmed AF
    Bioorg Chem; 2016 Dec; 69():48-63. PubMed ID: 27669120
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.