These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 31697382)

  • 1. Extrapolating In Vitro Screening Assay Data for Thyroperoxidase Inhibition to Predict Serum Thyroid Hormones in the Rat.
    Hassan I; El-Masri H; Ford J; Brennan A; Handa S; Paul Friedman K; Gilbert ME
    Toxicol Sci; 2020 Feb; 173(2):280-292. PubMed ID: 31697382
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cross-species analysis of thyroperoxidase inhibition by xenobiotics demonstrates conservation of response between pig and rat.
    Paul KB; Hedge JM; Macherla C; Filer DL; Burgess E; Simmons SO; Crofton KM; Hornung MW
    Toxicology; 2013 Oct; 312():97-107. PubMed ID: 23959146
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries.
    Paul Friedman K; Watt ED; Hornung MW; Hedge JM; Judson RS; Crofton KM; Houck KA; Simmons SO
    Toxicol Sci; 2016 May; 151(1):160-80. PubMed ID: 26884060
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A comparison of potency differences among thyroid peroxidase (TPO) inhibitors to induce developmental toxicity and other thyroid gland-linked toxicities in humans and rats.
    Motonaga K; Ota M; Odawara K; Saito S; Welsch F
    Regul Toxicol Pharmacol; 2016 Oct; 80():283-90. PubMed ID: 27350053
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of antithyroid agents 6-propyl-2-thiouracil and 1-mehtyl-2-mercaptoimidazole on human thyroid iodine peroxidase.
    Nagasaka A; Hidaka H
    J Clin Endocrinol Metab; 1976 Jul; 43(1):152-8. PubMed ID: 947933
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Methimazole and propylthiouracil increase cellular thyroid peroxidase activity and thyroid peroxidase mRNA in cultured porcine thyroid follicles.
    Sugawara M; Sugawara Y; Wen K
    Thyroid; 1999 May; 9(5):513-8. PubMed ID: 10365684
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of a thyroperoxidase inhibition assay for high-throughput screening.
    Paul KB; Hedge JM; Rotroff DM; Hornung MW; Crofton KM; Simmons SO
    Chem Res Toxicol; 2014 Mar; 27(3):387-99. PubMed ID: 24383450
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanism of action of thioureylene antithyroid drugs in the rat: possible inactivation of thyroid peroxidase by propylthiouracil.
    Shiroozu A; Taurog A; Engler H; Dorris ML
    Endocrinology; 1983 Jul; 113(1):362-70. PubMed ID: 6861708
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neurodevelopment and Thyroid Hormone Synthesis Inhibition in the Rat: Quantitative Understanding Within the Adverse Outcome Pathway Framework.
    Hassan I; El-Masri H; Kosian PA; Ford J; Degitz SJ; Gilbert ME
    Toxicol Sci; 2017 Nov; 160(1):57-73. PubMed ID: 28973696
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Thyroid organotypic rat and human cultures used to investigate drug effects on thyroid function, hormone synthesis and release pathways.
    Vickers AE; Heale J; Sinclair JR; Morris S; Rowe JM; Fisher RL
    Toxicol Appl Pharmacol; 2012 Apr; 260(1):81-8. PubMed ID: 22342233
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vitro assessment of thyroid peroxidase inhibition by chemical exposure: comparison of cell models and detection methods.
    Liu R; Novák J; Hilscherová K
    Arch Toxicol; 2024 Aug; 98(8):2631-2645. PubMed ID: 38796608
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A reexamination of the proposed inactivation of thyroid peroxidase in the rat thyroid by propylthiouracil.
    Taurog A; Dorris ML
    Endocrinology; 1989 Jun; 124(6):3038-42. PubMed ID: 2656250
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanistic Computational Model for Extrapolating In Vitro Thyroid Peroxidase (TPO) Inhibition Data to Predict Serum Thyroid Hormone Levels in Rats.
    Handa S; Hassan I; Gilbert M; El-Masri H
    Toxicol Sci; 2021 Aug; 183(1):36-48. PubMed ID: 34117770
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metabolism of 35S- and 14C-labeled propylthiouracil in a model in vitro system containing thyroid peroxidase.
    Taurog A; Dorris ML; Guziec FS; Uetrecht JP
    Endocrinology; 1989 Jun; 124(6):3030-7. PubMed ID: 2656249
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Testing for heterotopia formation in rats after developmental exposure to selected in vitro inhibitors of thyroperoxidase.
    Ramhøj L; Frädrich C; Svingen T; Scholze M; Wirth EK; Rijntjes E; Köhrle J; Kortenkamp A; Axelstad M
    Environ Pollut; 2021 Aug; 283():117135. PubMed ID: 33892370
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Perinatal exposure to the thyroperoxidase inhibitors methimazole and amitrole perturbs thyroid hormone system signaling and alters motor activity in rat offspring.
    Ramhøj L; Svingen T; Frädrich C; Rijntjes E; Wirth EK; Pedersen K; Köhrle J; Axelstad M
    Toxicol Lett; 2022 Jan; 354():44-55. PubMed ID: 34757178
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Preferential inhibition of thyroxine and 3,5,3'-triiodothyronine formation by propylthiouracil and methylmercaptoimidazole in thyroid peroxidase-catalyzed iodination of thyroglobulin.
    Engler H; Taurog A; Dorris ML
    Endocrinology; 1982 Jan; 110(1):190-7. PubMed ID: 7053983
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibitory effects of methimazole and propylthiouracil on iodotyrosine deiodinase 1 in thyrocytes.
    Yoshihara A; Luo Y; Ishido Y; Usukura K; Oda K; Sue M; Kawashima A; Hiroi N; Suzuki K
    Endocr J; 2019 Apr; 66(4):349-357. PubMed ID: 30814441
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The selenium analog of 6-propylthiouracil. Measurement of its inhibitory effect on type I iodothyronine deiodinase and of its antithyroid activity.
    Taurog A; Dorris ML; Hu WX; Guziec FS
    Biochem Pharmacol; 1995 Mar; 49(5):701-9. PubMed ID: 7887985
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling.
    Leonard JA; Tan YM; Gilbert M; Isaacs K; El-Masri H
    Toxicol Sci; 2016 May; 151(1):57-70. PubMed ID: 26865668
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.