These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. Combined MEK and STAT3 Inhibition Uncovers Stromal Plasticity by Enriching for Cancer-Associated Fibroblasts With Mesenchymal Stem Cell-Like Features to Overcome Immunotherapy Resistance in Pancreatic Cancer. Datta J; Dai X; Bianchi A; De Castro Silva I; Mehra S; Garrido VT; Lamichhane P; Singh SP; Zhou Z; Dosch AR; Messaggio F; Ban Y; Umland O; Hosein PJ; Nagathihalli NS; Merchant NB Gastroenterology; 2022 Dec; 163(6):1593-1612. PubMed ID: 35948109 [TBL] [Abstract][Full Text] [Related]
5. Single-cell RNA sequencing reveals compartmental remodeling of tumor-infiltrating immune cells induced by anti-CD47 targeting in pancreatic cancer. Pan Y; Lu F; Fei Q; Yu X; Xiong P; Yu X; Dang Y; Hou Z; Lin W; Lin X; Zhang Z; Pan M; Huang H J Hematol Oncol; 2019 Nov; 12(1):124. PubMed ID: 31771616 [TBL] [Abstract][Full Text] [Related]
6. Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice. Peran I; Dakshanamurthy S; McCoy MD; Mavropoulos A; Allo B; Sebastian A; Hum NR; Sprague SC; Martin KA; Pishvaian MJ; Vietsch EE; Wellstein A; Atkins MB; Weiner LM; Quong AA; Loots GG; Yoo SS; Assefnia S; Byers SW Gastroenterology; 2021 Mar; 160(4):1359-1372.e13. PubMed ID: 33307028 [TBL] [Abstract][Full Text] [Related]
7. myCAFs are better than yours: targeting myofibroblasts potentiates immunotherapy. Monteran L; Erez N Trends Cancer; 2023 Jan; 9(1):1-2. PubMed ID: 36371342 [TBL] [Abstract][Full Text] [Related]
8. Single-Cell Analysis Reveals Fibroblast Clusters Linked to Immunotherapy Resistance in Cancer. Kieffer Y; Hocine HR; Gentric G; Pelon F; Bernard C; Bourachot B; Lameiras S; Albergante L; Bonneau C; Guyard A; Tarte K; Zinovyev A; Baulande S; Zalcman G; Vincent-Salomon A; Mechta-Grigoriou F Cancer Discov; 2020 Sep; 10(9):1330-1351. PubMed ID: 32434947 [TBL] [Abstract][Full Text] [Related]
9. Targeting cancer-associated fibroblast autophagy renders pancreatic cancer eradicable with immunochemotherapy by inhibiting adaptive immune resistance. Zhang X; Lao M; Yang H; Sun K; Dong Y; He L; Jiang X; Wu H; Jiang Y; Li M; Ying H; Liu X; Xu J; Chen Y; Zhang H; Zhou R; Gao J; Bai X; Liang T Autophagy; 2024 Jun; 20(6):1314-1334. PubMed ID: 38174993 [TBL] [Abstract][Full Text] [Related]
10. BNIP3+ fibroblasts associated with hypoxia and inflammation predict prognosis and immunotherapy response in pancreatic ductal adenocarcinoma. Gao B; Hu G; Sun B; Li W; Yang H J Transl Med; 2024 Oct; 22(1):937. PubMed ID: 39402590 [TBL] [Abstract][Full Text] [Related]
11. Targeting leucine-rich repeat serine/threonine-protein kinase 2 sensitizes pancreatic ductal adenocarcinoma to anti-PD-L1 immunotherapy. Sun K; Zhang X; Lao M; He L; Wang S; Yang H; Xu J; Tang J; Hong Z; Song J; Guo C; Li M; Liu X; Chen Y; Zhang H; Zhou J; Lin J; Zhang S; Hong Y; Huang J; Liang T; Bai X Mol Ther; 2023 Oct; 31(10):2929-2947. PubMed ID: 37515321 [TBL] [Abstract][Full Text] [Related]
12. TGFβ-blockade uncovers stromal plasticity in tumors by revealing the existence of a subset of interferon-licensed fibroblasts. Grauel AL; Nguyen B; Ruddy D; Laszewski T; Schwartz S; Chang J; Chen J; Piquet M; Pelletier M; Yan Z; Kirkpatrick ND; Wu J; deWeck A; Riester M; Hims M; Geyer FC; Wagner J; MacIsaac K; Deeds J; Diwanji R; Jayaraman P; Yu Y; Simmons Q; Weng S; Raza A; Minie B; Dostalek M; Chikkegowda P; Ruda V; Iartchouk O; Chen N; Thierry R; Zhou J; Pruteanu-Malinici I; Fabre C; Engelman JA; Dranoff G; Cremasco V Nat Commun; 2020 Dec; 11(1):6315. PubMed ID: 33298926 [TBL] [Abstract][Full Text] [Related]
13. CDK1/2/5 inhibition overcomes IFNG-mediated adaptive immune resistance in pancreatic cancer. Huang J; Chen P; Liu K; Liu J; Zhou B; Wu R; Peng Q; Liu ZX; Li C; Kroemer G; Lotze M; Zeh H; Kang R; Tang D Gut; 2021 May; 70(5):890-899. PubMed ID: 32816920 [TBL] [Abstract][Full Text] [Related]
14. ERK Inhibition Improves Anti-PD-L1 Immune Checkpoint Blockade in Preclinical Pancreatic Ductal Adenocarcinoma. Henry KE; Mack KN; Nagle VL; Cornejo M; Michel AO; Fox IL; Davydova M; Dilling TR; Pillarsetty N; Lewis JS Mol Cancer Ther; 2021 Oct; 20(10):2026-2034. PubMed ID: 34349003 [TBL] [Abstract][Full Text] [Related]
15. Identification of Functional Heterogeneity of Carcinoma-Associated Fibroblasts with Distinct IL6-Mediated Therapy Resistance in Pancreatic Cancer. McAndrews KM; Chen Y; Darpolor JK; Zheng X; Yang S; Carstens JL; Li B; Wang H; Miyake T; Correa de Sampaio P; Kirtley ML; Natale M; Wu CC; Sugimoto H; LeBleu VS; Kalluri R Cancer Discov; 2022 Jun; 12(6):1580-1597. PubMed ID: 35348629 [TBL] [Abstract][Full Text] [Related]
16. IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma. Biffi G; Oni TE; Spielman B; Hao Y; Elyada E; Park Y; Preall J; Tuveson DA Cancer Discov; 2019 Feb; 9(2):282-301. PubMed ID: 30366930 [TBL] [Abstract][Full Text] [Related]
17. IR-780 Dye-based Targeting of Cancer-associated Fibroblasts Improves Cancer Immunotherapy by Increasing Intra-tumoral T Lymphocytes Infiltration. Yang W; Chen Z; Qu L; Zhang C; Chen H; Zheng J; Chen W; Tan X; Shi C Curr Cancer Drug Targets; 2024; 24(6):642-653. PubMed ID: 38310462 [TBL] [Abstract][Full Text] [Related]
18. Deciphering the Prognostic Implications of the Components and Signatures in the Immune Microenvironment of Pancreatic Ductal Adenocarcinoma. Tang R; Liu X; Liang C; Hua J; Xu J; Wang W; Meng Q; Liu J; Zhang B; Yu X; Shi S Front Immunol; 2021; 12():648917. PubMed ID: 33777046 [No Abstract] [Full Text] [Related]
19. Anti-metastatic potential of somatostatin analog SOM230: Indirect pharmacological targeting of pancreatic cancer-associated fibroblasts. Moatassim-Billah S; Duluc C; Samain R; Jean C; Perraud A; Decaup E; Cassant-Sourdy S; Bakri Y; Selves J; Schmid H; Martineau Y; Mathonnet M; Pyronnet S; Bousquet C Oncotarget; 2016 Jul; 7(27):41584-41598. PubMed ID: 27177087 [TBL] [Abstract][Full Text] [Related]
20. Senescence Defines a Distinct Subset of Myofibroblasts That Orchestrates Immunosuppression in Pancreatic Cancer. Belle JI; Sen D; Baer JM; Liu X; Lander VE; Ye J; Sells BE; Knolhoff BL; Faiz A; Kang LI; Qian G; Fields RC; Ding L; Kim H; Provenzano PP; Stewart SA; DeNardo DG Cancer Discov; 2024 Jul; 14(7):1324-1355. PubMed ID: 38683144 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]