184 related articles for article (PubMed ID: 31703090)
1. UM171 induces a homeostatic inflammatory-detoxification response supporting human HSC self-renewal.
Chagraoui J; Lehnertz B; Girard S; Spinella JF; Fares I; Tomellini E; Mayotte N; Corneau S; MacRae T; Simon L; Sauvageau G
PLoS One; 2019; 14(11):e0224900. PubMed ID: 31703090
[TBL] [Abstract][Full Text] [Related]
2. Gram-Scale Laboratory Synthesis of UM171, a Potent Agonist of Human Hematopoietic Stem Cell Self-Renewal.
Ali S; Yu SM; Yao ZJ
J Org Chem; 2016 Nov; 81(21):10236-10241. PubMed ID: 27337543
[TBL] [Abstract][Full Text] [Related]
3. EPCR expression marks UM171-expanded CD34
Fares I; Chagraoui J; Lehnertz B; MacRae T; Mayotte N; Tomellini E; Aubert L; Roux PP; Sauvageau G
Blood; 2017 Jun; 129(25):3344-3351. PubMed ID: 28408459
[TBL] [Abstract][Full Text] [Related]
4. Lysine-specific demethylase 1A restricts ex vivo propagation of human HSCs and is a target of UM171.
Subramaniam A; Žemaitis K; Talkhoncheh MS; Yudovich D; Bäckström A; Debnath S; Chen J; Jain MV; Galeev R; Gaetani M; Zubarev RA; Larsson J
Blood; 2020 Nov; 136(19):2151-2161. PubMed ID: 32582923
[TBL] [Abstract][Full Text] [Related]
5. Pyrimidoindole derivative UM171 enhances derivation of hematopoietic progenitor cells from human pluripotent stem cells.
Li X; Xia C; Wang T; Liu L; Zhao Q; Yang D; Hu F; Zhang M; Huang K; Geng Y; Zheng Y; Guan Y; Wu H; Chen X; Pan G; Chen J; Du J; Wang J
Stem Cell Res; 2017 May; 21():32-39. PubMed ID: 28368243
[TBL] [Abstract][Full Text] [Related]
6. Small molecule regulation of normal and leukemic stem cells.
Fares I; Rivest-Khan L; Cohen S; Sauvageau G
Curr Opin Hematol; 2015 Jul; 22(4):309-16. PubMed ID: 26049751
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and evaluation of pyrimidoindole analogs in umbilical cord blood ex vivo expansion.
Feng Y; Xie XY; Yang YQ; Sun YT; Ma WH; Zhou PJ; Li ZY; Liu HQ; Wang YF; Huang YS
Eur J Med Chem; 2019 Jul; 174():181-197. PubMed ID: 31035239
[TBL] [Abstract][Full Text] [Related]
8. UM171 expands distinct types of myeloid and NK progenitors from human pluripotent stem cells.
Mesquitta WT; Wandsnider M; Kang H; Thomson J; Moskvin O; Suknuntha K; Slukvin II
Sci Rep; 2019 Apr; 9(1):6622. PubMed ID: 31036928
[TBL] [Abstract][Full Text] [Related]
9. Effects of signaling pathway inhibitors on hematopoietic stem cells.
Jiang Y; Xu Z; Ma N; Yin L; Hao C; Li J
Mol Med Rep; 2021 Jan; 23(1):. PubMed ID: 33179097
[TBL] [Abstract][Full Text] [Related]
10. [Regulatory role of HOXB4 in self-renewal of hematopoietic stem cells - review].
Zheng CL; Zhou B; Lu M
Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2007 Jun; 15(3):647-51. PubMed ID: 17605886
[TBL] [Abstract][Full Text] [Related]
11. [Regulation of hematopoietic stem cell homeostasis by Spred1].
Tadokoro Y; Hirao A
Rinsho Ketsueki; 2018; 59(11):2441-2448. PubMed ID: 30531141
[TBL] [Abstract][Full Text] [Related]
12. Fluoranthene-Induced Cytotoxicity and Direct Effect of Aryl Hydrocarbon Receptor Antagonist on Hematopoietic Stem Cell Differentiation.
Yang SH; Kang MG; Kim HR; Lee YE; Na BR; Lee JH; Shin JH; Shin MG
Ann Lab Med; 2019 Nov; 39(6):580-583. PubMed ID: 31240888
[No Abstract] [Full Text] [Related]
13. Novel chemical attempts at ex vivo hematopoietic stem cell expansion.
Zhang Y; Gao Y
Int J Hematol; 2016 May; 103(5):519-29. PubMed ID: 26910241
[TBL] [Abstract][Full Text] [Related]
14. Notch2 blockade enhances hematopoietic stem cell mobilization and homing.
Wang W; Yu S; Myers J; Wang Y; Xin WW; Albakri M; Xin AW; Li M; Huang AY; Xin W; Siebel CW; Lazarus HM; Zhou L
Haematologica; 2017 Oct; 102(10):1785-1795. PubMed ID: 28729299
[TBL] [Abstract][Full Text] [Related]
15. KBTBD4-mediated reduction of MYC is critical for hematopoietic stem cell expansion upon UM171 treatment.
Chagraoui J; Girard S; Mallinger L; Mayotte N; Tellechea MF; Sauvageau G
Blood; 2024 Mar; 143(10):882-894. PubMed ID: 38207291
[TBL] [Abstract][Full Text] [Related]
16. Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal.
Fares I; Chagraoui J; Gareau Y; Gingras S; Ruel R; Mayotte N; Csaszar E; Knapp DJ; Miller P; Ngom M; Imren S; Roy DC; Watts KL; Kiem HP; Herrington R; Iscove NN; Humphries RK; Eaves CJ; Cohen S; Marinier A; Zandstra PW; Sauvageau G
Science; 2014 Sep; 345(6203):1509-12. PubMed ID: 25237102
[TBL] [Abstract][Full Text] [Related]
17. Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal.
Xie SZ; Garcia-Prat L; Voisin V; Ferrari R; Gan OI; Wagenblast E; Kaufmann KB; Zeng AGX; Takayanagi SI; Patel I; Lee EK; Jargstorf J; Holmes G; Romm G; Pan K; Shoong M; Vedi A; Luberto C; Minden MD; Bader GD; Laurenti E; Dick JE
Cell Stem Cell; 2019 Nov; 25(5):639-653.e7. PubMed ID: 31631013
[TBL] [Abstract][Full Text] [Related]
18. To harness stem cells by manipulation of energetic metabolism.
Loncaric D; Duchez P; Ivanovic Z
Transfus Clin Biol; 2017 Nov; 24(4):468-471. PubMed ID: 28602675
[TBL] [Abstract][Full Text] [Related]
19. Recombinant TAT-BMI-1 fusion protein induces ex vivo expansion of human umbilical cord blood-derived hematopoietic stem cells.
Codispoti B; Rinaldo N; Chiarella E; Lupia M; Spoleti CB; Marafioti MG; Aloisio A; Scicchitano S; Giordano M; Nappo G; Lucchino V; Moore MAS; Zhou P; Mesuraca M; Bond HM; Morrone G
Oncotarget; 2017 Jul; 8(27):43782-43798. PubMed ID: 28187462
[TBL] [Abstract][Full Text] [Related]
20. GRK6 regulates ROS response and maintains hematopoietic stem cell self-renewal.
Le Q; Yao W; Chen Y; Yan B; Liu C; Yuan M; Zhou Y; Ma L
Cell Death Dis; 2016 Nov; 7(11):e2478. PubMed ID: 27882944
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
