BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

218 related articles for article (PubMed ID: 31703413)

  • 1. The Pathogenic TSH β-subunit Variant C105Vfs114X Causes a Modified Signaling Profile at TSHR.
    Kalveram L; Kleinau G; Szymańska K; Scheerer P; Rivero-Müller A; Grüters-Kieslich A; Biebermann H
    Int J Mol Sci; 2019 Nov; 20(22):. PubMed ID: 31703413
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A family with congenital hypothyroidism caused by a combination of loss-of-function mutations in the thyrotropin receptor and adenylate cyclase-stimulating G alpha-protein subunit genes.
    Lado-Abeal J; Castro-Piedras I; Palos-Paz F; Labarta-Aizpún JI; Albero-Gamboa R
    Thyroid; 2011 Feb; 21(2):103-9. PubMed ID: 21186955
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TSH induces metallothionein 1 in thyrocytes via Gq/11- and PKC-dependent signaling.
    Bäck CM; Stohr S; Schäfer EA; Biebermann H; Boekhoff I; Breit A; Gudermann T; Büch TR
    J Mol Endocrinol; 2013; 51(1):79-90. PubMed ID: 23613280
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nonclassic TSH resistance: TSHR mutation carriers with discrepantly high thyroidal iodine uptake.
    Narumi S; Nagasaki K; Ishii T; Muroya K; Asakura Y; Adachi M; Hasegawa T
    J Clin Endocrinol Metab; 2011 Aug; 96(8):E1340-5. PubMed ID: 21677043
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Substitutions of different regions of the third cytoplasmic loop of the thyrotropin (TSH) receptor have selective effects on constitutive, TSH-, and TSH receptor autoantibody-stimulated phosphoinositide and 3',5'-cyclic adenosine monophosphate signal generation.
    Kosugi S; Okajima F; Ban T; Hidaka A; Shenker A; Kohn LD
    Mol Endocrinol; 1993 Aug; 7(8):1009-20. PubMed ID: 7901757
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inactivation of a Frameshift TSH Receptor Variant Val711Phefs*18 is Due to Acquisition of a Hydrophobic Degron.
    Sugisawa C; Ono M; Kashimada K; Hasegawa T; Narumi S
    J Clin Endocrinol Metab; 2021 Jan; 106(1):e265-e272. PubMed ID: 33108452
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Congenital secondary hypothyroidism due to a mutation C105Vfs114X thyrotropin-beta mutation: genetic study of five unrelated families from Switzerland and Argentina.
    Deladoëy J; Vuissoz JM; Domené HM; Malik N; Gruneiro-Papendieck L; Chiesa A; Heinrich JJ; Mullis PE
    Thyroid; 2003 Jun; 13(6):553-9. PubMed ID: 12930599
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Occupancy of both sites on the thyrotropin (TSH) receptor dimer is necessary for phosphoinositide signaling.
    Allen MD; Neumann S; Gershengorn MC
    FASEB J; 2011 Oct; 25(10):3687-94. PubMed ID: 21705666
    [TBL] [Abstract][Full Text] [Related]  

  • 9. G13-dependent activation of MAPK by thyrotropin.
    Büch TR; Biebermann H; Kalwa H; Pinkenburg O; Hager D; Barth H; Aktories K; Breit A; Gudermann T
    J Biol Chem; 2008 Jul; 283(29):20330-41. PubMed ID: 18445595
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Small-molecule thyrotropin receptor agonist activates naturally occurring thyrotropin-insensitive mutants and reveals their distinct cyclic adenosine monophosphate signal persistence.
    Allen MD; Neumann S; Gershengorn MC
    Thyroid; 2011 Aug; 21(8):907-12. PubMed ID: 21745101
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Constitutive activation of the thyroid-stimulating hormone receptor (TSHR) by mutating Ile691 in the cytoplasmic tail segment.
    Liu Z; Fan F; Xiao X; Sun Y
    PLoS One; 2011 Jan; 6(1):e16335. PubMed ID: 21283701
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of the cAMP and MAPK pathways in the transformation of mouse 3T3 fibroblasts by a TSHR gene constitutively activated by point mutation.
    Du Villard JA; Wicker R; Crespo P; Russo D; Filetti S; Gutkind JS; Sarasin A; Suárez HG
    Oncogene; 2000 Oct; 19(42):4896-905. PubMed ID: 11039907
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparative proteomic analysis to dissect differences in signal transduction in activating TSH receptor mutations in the thyroid.
    Krause K; Boisnard A; Ihling C; Ludgate M; Eszlinger M; Krohn K; Sinz A; Fuhrer D
    Int J Biochem Cell Biol; 2012 Feb; 44(2):290-301. PubMed ID: 22074661
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural determinants for G-protein activation and specificity in the third intracellular loop of the thyroid-stimulating hormone receptor.
    Claus M; Neumann S; Kleinau G; Krause G; Paschke R
    J Mol Med (Berl); 2006 Nov; 84(11):943-54. PubMed ID: 16955277
    [TBL] [Abstract][Full Text] [Related]  

  • 15. New pathogenic thyrotropin receptor mutations decipher differentiated activity switching at a conserved helix 6 motif of family A GPCR.
    Biebermann H; Winkler F; Handke D; Teichmann A; Gerling B; Cameron F; Eichhorst J; Grüters A; Wiesner B; Kühnen P; Krude H; Kleinau G
    J Clin Endocrinol Metab; 2012 Feb; 97(2):E228-32. PubMed ID: 22112806
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Intracellular entrapment of wild-type TSH receptor by oligomerization with mutants linked to dominant TSH resistance.
    Calebiro D; de Filippis T; Lucchi S; Covino C; Panigone S; Beck-Peccoz P; Dunlap D; Persani L
    Hum Mol Genet; 2005 Oct; 14(20):2991-3002. PubMed ID: 16135555
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Thyrotropin Causes Dose-dependent Biphasic Regulation of cAMP Production Mediated by G
    Neumann S; Malik SS; Marcus-Samuels B; Eliseeva E; Jang D; Klubo-Gwiezdzinska J; Krieger CC; Gershengorn MC
    Mol Pharmacol; 2020 Jan; 97(1):2-8. PubMed ID: 31704717
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Central Hypothyroidism Due to a TRHR Mutation Causing Impaired Ligand Affinity and Transactivation of Gq.
    García M; González de Buitrago J; Jiménez-Rosés M; Pardo L; Hinkle PM; Moreno JC
    J Clin Endocrinol Metab; 2017 Jul; 102(7):2433-2442. PubMed ID: 28419241
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Functional studies of new TSH receptor (TSHr) mutations identified in patients affected by hypothyroidism or isolated hyperthyrotrophinaemia.
    De Marco G; Agretti P; Camilot M; Teofoli F; Tatò L; Vitti P; Pinchera A; Tonacchera M
    Clin Endocrinol (Oxf); 2009 Feb; 70(2):335-8. PubMed ID: 18727713
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Subunit interactions influence TSHR multimerization.
    Latif R; Michalek K; Davies TF
    Mol Endocrinol; 2010 Oct; 24(10):2009-18. PubMed ID: 20719860
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.