These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

629 related articles for article (PubMed ID: 31704924)

  • 1. 4-Octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to exert anti-inflammatory effects.
    Liao ST; Han C; Xu DQ; Fu XW; Wang JS; Kong LY
    Nat Commun; 2019 Nov; 10(1):5091. PubMed ID: 31704924
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity.
    Kornberg MD; Bhargava P; Kim PM; Putluri V; Snowman AM; Putluri N; Calabresi PA; Snyder SH
    Science; 2018 Apr; 360(6387):449-453. PubMed ID: 29599194
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
    Mills EL; Ryan DG; Prag HA; Dikovskaya D; Menon D; Zaslona Z; Jedrychowski MP; Costa ASH; Higgins M; Hams E; Szpyt J; Runtsch MC; King MS; McGouran JF; Fischer R; Kessler BM; McGettrick AF; Hughes MM; Carroll RG; Booty LM; Knatko EV; Meakin PJ; Ashford MLJ; Modis LK; Brunori G; Sévin DC; Fallon PG; Caldwell ST; Kunji ERS; Chouchani ET; Frezza C; Dinkova-Kostova AT; Hartley RC; Murphy MP; O'Neill LA
    Nature; 2018 Apr; 556(7699):113-117. PubMed ID: 29590092
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 4-Octyl Itaconate Activates Nrf2 Signaling to Inhibit Pro-Inflammatory Cytokine Production in Peripheral Blood Mononuclear Cells of Systemic Lupus Erythematosus Patients.
    Tang C; Wang X; Xie Y; Cai X; Yu N; Hu Y; Zheng Z
    Cell Physiol Biochem; 2018; 51(2):979-990. PubMed ID: 30466076
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response.
    Sun KA; Li Y; Meliton AY; Woods PS; Kimmig LM; Cetin-Atalay R; Hamanaka RB; Mutlu GM
    Elife; 2020 Apr; 9():. PubMed ID: 32255424
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation.
    Bailey JD; Diotallevi M; Nicol T; McNeill E; Shaw A; Chuaiphichai S; Hale A; Starr A; Nandi M; Stylianou E; McShane H; Davis S; Fischer R; Kessler BM; McCullagh J; Channon KM; Crabtree MJ
    Cell Rep; 2019 Jul; 28(1):218-230.e7. PubMed ID: 31269442
    [TBL] [Abstract][Full Text] [Related]  

  • 7. S-glycosylation-based cysteine profiling reveals regulation of glycolysis by itaconate.
    Qin W; Qin K; Zhang Y; Jia W; Chen Y; Cheng B; Peng L; Chen N; Liu Y; Zhou W; Wang YL; Chen X; Wang C
    Nat Chem Biol; 2019 Oct; 15(10):983-991. PubMed ID: 31332308
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 4-octyl itaconate as a metabolite derivative inhibits inflammation via alkylation of STING.
    Li W; Li Y; Kang J; Jiang H; Gong W; Chen L; Wu C; Liu M; Wu X; Zhao Y; Ren J
    Cell Rep; 2023 Mar; 42(3):112145. PubMed ID: 36862550
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Deoxyelephantopin decreases the release of inflammatory cytokines in macrophage associated with attenuation of aerobic glycolysis via modulation of PKM2.
    Pan L; Hu L; Zhang L; Xu H; Chen Y; Bian Q; Zhu A; Wu H
    Int Immunopharmacol; 2020 Feb; 79():106048. PubMed ID: 31863924
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 4-Octyl Itaconate Alleviates Lipopolysaccharide-Induced Acute Lung Injury in Mice by Inhibiting Oxidative Stress and Inflammation.
    Li Y; Chen X; Zhang H; Xiao J; Yang C; Chen W; Wei Z; Chen X; Liu J
    Drug Des Devel Ther; 2020; 14():5547-5558. PubMed ID: 33364751
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Cell-Permeable Derivative of the Immunoregulatory Metabolite Itaconate, 4-Octyl Itaconate, Is Anti-Fibrotic in Systemic Sclerosis.
    Henderson J; Dayalan Naidu S; Dinkova-Kostova AT; Przyborski S; Stratton R; O Reilly S
    Cells; 2021 Aug; 10(8):. PubMed ID: 34440821
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evolved resistance to partial GAPDH inhibition results in loss of the Warburg effect and in a different state of glycolysis.
    Liberti MV; Allen AE; Ramesh V; Dai Z; Singleton KR; Guo Z; Liu JO; Wood KC; Locasale JW
    J Biol Chem; 2020 Jan; 295(1):111-124. PubMed ID: 31748414
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 4-Octyl itaconate attenuates glycemic deterioration by regulating macrophage polarization in mouse models of type 1 diabetes.
    He S; Zhao Y; Wang G; Ke Q; Wu N; Lu L; Wu J; Sun S; Jin W; Zhang W; Zhou J
    Mol Med; 2023 Mar; 29(1):31. PubMed ID: 36918798
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage.
    Németh B; Doczi J; Csete D; Kacso G; Ravasz D; Adams D; Kiss G; Nagy AM; Horvath G; Tretter L; Mócsai A; Csépányi-Kömi R; Iordanov I; Adam-Vizi V; Chinopoulos C
    FASEB J; 2016 Jan; 30(1):286-300. PubMed ID: 26358042
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Octyl itaconate inhibits osteoclastogenesis by suppressing Hrd1 and activating Nrf2 signaling.
    Sun X; Zhang B; Pan X; Huang H; Xie Z; Ma Y; Hu B; Wang J; Chen Z; Shi P
    FASEB J; 2019 Nov; 33(11):12929-12940. PubMed ID: 31490085
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interferon Gamma Induces Reversible Metabolic Reprogramming of M1 Macrophages to Sustain Cell Viability and Pro-Inflammatory Activity.
    Wang F; Zhang S; Jeon R; Vuckovic I; Jiang X; Lerman A; Folmes CD; Dzeja PD; Herrmann J
    EBioMedicine; 2018 Apr; 30():303-316. PubMed ID: 29463472
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages.
    Runtsch MC; Angiari S; Hooftman A; Wadhwa R; Zhang Y; Zheng Y; Spina JS; Ruzek MC; Argiriadi MA; McGettrick AF; Mendez RS; Zotta A; Peace CG; Walsh A; Chirillo R; Hams E; Fallon PG; Jayamaran R; Dua K; Brown AC; Kim RY; Horvat JC; Hansbro PM; Wang C; O'Neill LAJ
    Cell Metab; 2022 Mar; 34(3):487-501.e8. PubMed ID: 35235776
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 4-Octyl-Itaconate and Dimethyl Fumarate Inhibit COX2 Expression and Prostaglandin Production in Macrophages.
    Diskin C; Zotta A; Corcoran SE; Tyrrell VJ; Zaslona Z; O'Donnell VB; O'Neill LAJ
    J Immunol; 2021 Nov; 207(10):2561-2569. PubMed ID: 34635585
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Protein-Protein Interaction Inhibitor Reveals a Non-catalytic Role for GAPDH Oligomerization in Cell Death.
    Qvit N; Joshi AU; Cunningham AD; Ferreira JC; Mochly-Rosen D
    J Biol Chem; 2016 Jun; 291(26):13608-21. PubMed ID: 27129213
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glycolytic Stimulation Is Not a Requirement for M2 Macrophage Differentiation.
    Wang F; Zhang S; Vuckovic I; Jeon R; Lerman A; Folmes CD; Dzeja PP; Herrmann J
    Cell Metab; 2018 Sep; 28(3):463-475.e4. PubMed ID: 30184486
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.