BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

426 related articles for article (PubMed ID: 31707709)

  • 1. Allosteric Modulators of Protein-Protein Interactions (PPIs).
    Ni D; Liu N; Sheng C
    Adv Exp Med Biol; 2019; 1163():313-334. PubMed ID: 31707709
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Emerging roles of allosteric modulators in the regulation of protein-protein interactions (PPIs): A new paradigm for PPI drug discovery.
    Ni D; Lu S; Zhang J
    Med Res Rev; 2019 Nov; 39(6):2314-2342. PubMed ID: 30957264
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development of Allosteric Modulators of Voltage-Gated Na
    Dvorak NM; Wadsworth PA; Wang P; Zhou J; Laezza F
    Curr Top Med Chem; 2021; 21(10):841-848. PubMed ID: 34036922
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Computational methods-guided design of modulators targeting protein-protein interactions (PPIs).
    Qiu Y; Li X; He X; Pu J; Zhang J; Lu S
    Eur J Med Chem; 2020 Dec; 207():112764. PubMed ID: 32871340
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Allosteric Methods and Their Applications: Facilitating the Discovery of Allosteric Drugs and the Investigation of Allosteric Mechanisms.
    Lu S; Shen Q; Zhang J
    Acc Chem Res; 2019 Feb; 52(2):492-500. PubMed ID: 30688063
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Small Molecule Targeting of Protein-Protein Interactions through Allosteric Modulation of Dynamics.
    Cossins BP; Lawson AD
    Molecules; 2015 Sep; 20(9):16435-45. PubMed ID: 26378508
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Leveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as discovery target.
    Janero DR; Thakur GA
    Expert Opin Drug Discov; 2016 Dec; 11(12):1223-1237. PubMed ID: 27712124
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Strategies for the identification of allosteric modulators of G-protein-coupled receptors.
    Burford NT; Watson J; Bertekap R; Alt A
    Biochem Pharmacol; 2011 Mar; 81(6):691-702. PubMed ID: 21184747
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Opportunities and Challenges in the Discovery of Allosteric Modulators of GPCRs.
    Bartuzi D; Kaczor AA; Matosiuk D
    Methods Mol Biol; 2018; 1705():297-319. PubMed ID: 29188568
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Harnessing the druggability at orthosteric and allosteric sites of PD-1 for small molecule discovery by an integrated in silico pipeline.
    Mittal L; Tonk RK; Awasthi A; Asthana S
    Comput Biol Chem; 2023 Dec; 107():107965. PubMed ID: 37826990
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Harnessing allostery: a novel approach to drug discovery.
    Lu S; Li S; Zhang J
    Med Res Rev; 2014 Nov; 34(6):1242-85. PubMed ID: 24827416
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Allosteric Modulator Discovery: From Serendipity to Structure-Based Design.
    Lu S; He X; Ni D; Zhang J
    J Med Chem; 2019 Jul; 62(14):6405-6421. PubMed ID: 30817889
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rational Design of Peptide-Based Inhibitors Disrupting Protein-Protein Interactions.
    Wang X; Ni D; Liu Y; Lu S
    Front Chem; 2021; 9():682675. PubMed ID: 34017824
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Alternative modulation of protein-protein interactions by small molecules.
    Fischer G; Rossmann M; Hyvönen M
    Curr Opin Biotechnol; 2015 Dec; 35():78-85. PubMed ID: 25935873
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Benchmark Study Based on 2P2I
    Wang Z; Kang Y; Li D; Sun H; Dong X; Yao X; Xu L; Chang S; Li Y; Hou T
    J Phys Chem B; 2018 Mar; 122(9):2544-2555. PubMed ID: 29420886
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Computational elucidation of allosteric communication in proteins for allosteric drug design.
    Ni D; Liu Y; Kong R; Yu Z; Lu S; Zhang J
    Drug Discov Today; 2022 Aug; 27(8):2226-2234. PubMed ID: 35314339
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Designing Molecular Spanners to Throw in the Protein Networks.
    Serapian SA; Colombo G
    Chemistry; 2020 Apr; 26(21):4656-4670. PubMed ID: 31746512
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combining Allosteric and Orthosteric Drugs to Overcome Drug Resistance.
    Ni D; Li Y; Qiu Y; Pu J; Lu S; Zhang J
    Trends Pharmacol Sci; 2020 May; 41(5):336-348. PubMed ID: 32171554
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening.
    Zhou Q; Guo W; Dai A; Cai X; Vass M; de Graaf C; Shui W; Zhao S; Yang D; Wang MW
    Biomolecules; 2021 Jun; 11(7):. PubMed ID: 34201418
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Are the Apo Proteins Suitable for the Rational Discovery of Allosteric Drugs?
    An X; Lu S; Song K; Shen Q; Huang M; Yao X; Liu H; Zhang J
    J Chem Inf Model; 2019 Jan; 59(1):597-604. PubMed ID: 30525607
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.