BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 31710123)

  • 21. Synthesis and biological evaluation of novel benzyl-substituted (S)-phenylalanine derivatives as potent dipeptidyl peptidase 4 inhibitors.
    Liu Y; Si M; Tang L; Shangguan S; Wu H; Li J; Wu P; Ma X; Liu T; Hu Y
    Bioorg Med Chem; 2013 Sep; 21(18):5679-87. PubMed ID: 23938053
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Structure-Activity Relationship Analysis of Cocrystallized Gliptin-like Pyrrolidine, Trifluorophenyl, and Pyrimidine-2,4-Dione Dipeptidyl Peptidase-4 Inhibitors.
    Tomovic K; Ilic BS; Smelcerovic A
    J Med Chem; 2021 Jul; 64(14):9639-9648. PubMed ID: 34190540
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Discovery of potent, selective, and orally bioavailable quinoline-based dipeptidyl peptidase IV inhibitors targeting Lys554.
    Maezaki H; Banno Y; Miyamoto Y; Moritoh Y; Asakawa T; Kataoka O; Takeuchi K; Suzuki N; Ikedo K; Kosaka T; Sasaki M; Tsubotani S; Tani A; Funami M; Yamamoto Y; Tawada M; Aertgeerts K; Yano J; Oi S
    Bioorg Med Chem; 2011 Aug; 19(15):4482-98. PubMed ID: 21741847
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The highly potent and selective dipeptidyl peptidase IV inhibitors bearing a thienopyrimidine scaffold effectively treat type 2 diabetes.
    Deng J; Peng L; Zhang G; Lan X; Li C; Chen F; Zhou Y; Lin Z; Chen L; Dai R; Xu H; Yang L; Zhang X; Hu W
    Eur J Med Chem; 2011 Jan; 46(1):71-6. PubMed ID: 21106276
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Optimization of the benzamide fragment targeting the S
    Deng X; Wang N; Meng L; Zhou S; Huang J; Xing J; He L; Jiang W; Li Q
    Bioorg Chem; 2020 Jan; 94():103366. PubMed ID: 31640932
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Structural optimization of pyrazolo[1,5-a]pyrimidine derivatives as potent and highly selective DPP-4 inhibitors.
    Shen J; Deng X; Sun R; Tavallaie MS; Wang J; Cai Q; Lam C; Lei S; Fu L; Jiang F
    Eur J Med Chem; 2020 Dec; 208():112850. PubMed ID: 32987315
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Discovery and pharmacological characterization of N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide hydrochloride (anagliptin hydrochloride salt) as a potent and selective DPP-IV inhibitor.
    Kato N; Oka M; Murase T; Yoshida M; Sakairi M; Yamashita S; Yasuda Y; Yoshikawa A; Hayashi Y; Makino M; Takeda M; Mirensha Y; Kakigami T
    Bioorg Med Chem; 2011 Dec; 19(23):7221-7. PubMed ID: 22019046
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Non-competitive and selective dipeptidyl peptidase IV inhibitors with phenethylphenylphthalimide skeleton derived from thalidomide-related α-glucosidase inhibitors and liver X receptor antagonists.
    Motoshima K; Sugita K; Hashimoto Y; Ishikawa M
    Bioorg Med Chem Lett; 2011 May; 21(10):3041-5. PubMed ID: 21478015
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Nonpeptide small-molecular inhibitors of dipeptidyl peptidase IV: N-phenylphthalimide analogs.
    Shimazawa R; Takayama H; Kato F; Kato M; Hashimoto Y
    Bioorg Med Chem Lett; 1999 Feb; 9(4):559-62. PubMed ID: 10098663
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Discovery of 3H-imidazo[4,5-c]quinolin-4(5H)-ones as potent and selective dipeptidyl peptidase IV (DPP-4) inhibitors.
    Ikuma Y; Hochigai H; Kimura H; Nunami N; Kobayashi T; Uchiyama K; Furuta Y; Sakai M; Horiguchi M; Masui Y; Okazaki K; Sato Y; Nakahira H
    Bioorg Med Chem; 2012 Oct; 20(19):5864-83. PubMed ID: 22938786
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Surrogating and redirection of pyrazolo[1,5-a]pyrimidin-7(4H)-one core, a novel class of potent and selective DPP-4 inhibitors.
    Deng X; Shen J; Zhu H; Xiao J; Sun R; Xie F; Lam C; Wang J; Qiao Y; Tavallaie MS; Hu Y; Du Y; Li J; Fu L; Jiang F
    Bioorg Med Chem; 2018 Feb; 26(4):903-912. PubMed ID: 29373269
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Design, Synthesis and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel DPP-4 Inhibitors.
    Li Q; Zhou M; Han L; Cao Q; Wang X; Zhao L; Zhou J; Zhang H
    Chem Biol Drug Des; 2015 Oct; 86(4):849-56. PubMed ID: 25787859
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Structure based virtual screening of MDPI database: discovery of structurally diverse and novel DPP-IV inhibitors.
    Tanwar O; Tanwar L; Shaquiquzzaman M; Alam MM; Akhter M
    Bioorg Med Chem Lett; 2014 Aug; 24(15):3447-51. PubMed ID: 24948564
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Integrated Protocol to Design Potential Inhibitors of Dipeptidyl Peptidase- 4 (DPP-4).
    Pantaleão SQ; Philot EA; de Oliveira Almeida M; Lima AN; de Sairre MI; Scott AL; Honorio KM
    Curr Top Med Chem; 2020; 20(3):209-226. PubMed ID: 31878857
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Synthesis, evaluation and molecular docking of prolyl-fluoropyrrolidine derivatives as dipeptidyl peptidase IV inhibitors.
    Sharma M; Gupta M; Singh D; Kumar M; Kaur P
    Chem Biol Drug Des; 2013 Aug; 82(2):156-66. PubMed ID: 23581745
    [TBL] [Abstract][Full Text] [Related]  

  • 36. [Design, synthesis and in vitro activity of glycinamide-bearing compounds as DPP-IV inhibitors].
    Han B; Huan Y; Lin ZY; Li P; Shen ZF; Yin DL; Huang HH
    Yao Xue Xue Bao; 2010 Nov; 45(11):1379-84. PubMed ID: 21361038
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Synthesis and biological evaluation of all eight stereoisomers of DPP-IV inhibitor saxagliptin.
    Dong J; Gong Y; Liu J; Chen X; Wen X; Sun H
    Bioorg Med Chem; 2014 Feb; 22(4):1383-93. PubMed ID: 24457090
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Discovery of C-(1-aryl-cyclohexyl)-methylamines as selective, orally available inhibitors of dipeptidyl peptidase IV.
    Namoto K; Sirockin F; Ostermann N; Gessier F; Flohr S; Sedrani R; Gerhartz B; Trappe J; Hassiepen U; Duttaroy A; Ferreira S; Sutton JM; Clark DE; Fenton G; Beswick M; Baeschlin DK
    Bioorg Med Chem Lett; 2014 Feb; 24(3):731-6. PubMed ID: 24439847
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Discovery of potent dipeptidyl peptidase IV inhibitors through pharmacophore hybridization and hit-to-lead optimization.
    Zeng S; Xie H; Zeng LL; Lu X; Zhao X; Zhang GC; Tu ZC; Xu HJ; Yang L; Zhang XQ; Hu W
    Bioorg Med Chem; 2013 Apr; 21(7):1749-55. PubMed ID: 23434133
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synthesis and biological evaluation of xanthine derivatives on dipeptidyl peptidase 4.
    Lin K; Cai Z; Wang F; Zhang W; Zhou W
    Chem Pharm Bull (Tokyo); 2013; 61(4):477-82. PubMed ID: 23358258
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.