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6. Different analogues of farnesyl pyrophosphate inhibit squalene synthase and protein:farnesyltransferase to different extents. Cohen LH; Valentijn AR; Roodenburg L; Van Leeuwen RE; Huisman RH; Lutz RJ; Van der Marel GA; Van Boom JH Biochem Pharmacol; 1995 Mar; 49(6):839-45. PubMed ID: 7702642 [TBL] [Abstract][Full Text] [Related]
7. Stereospecific synthesis and biological evaluation of farnesyl diphosphate isomers. Shao Y; Eummer JT; Gibbs RA Org Lett; 1999 Aug; 1(4):627-30. PubMed ID: 10823190 [TBL] [Abstract][Full Text] [Related]
8. Isoprenoid biosynthesis in rat liver peroxisomes. Characterization of cis-prenyltransferase and squalene synthetase. Ericsson J; Appelkvist EL; Thelin A; Chojnacki T; Dallner G J Biol Chem; 1992 Sep; 267(26):18708-14. PubMed ID: 1527001 [TBL] [Abstract][Full Text] [Related]
9. Squalene synthase inhibition alters metabolism of nonsterols in rat liver. Keller RK Biochim Biophys Acta; 1996 Oct; 1303(3):169-79. PubMed ID: 8908150 [TBL] [Abstract][Full Text] [Related]
10. Purification to homogeneity and some properties of squalene synthetase. Sasiak K; Rilling HC Arch Biochem Biophys; 1988 Feb; 260(2):622-7. PubMed ID: 3277535 [TBL] [Abstract][Full Text] [Related]
11. A novel bisphosphonate inhibitor of squalene synthase combined with a statin or a nitrogenous bisphosphonate in vitro. Wasko BM; Smits JP; Shull LW; Wiemer DF; Hohl RJ J Lipid Res; 2011 Nov; 52(11):1957-64. PubMed ID: 21903868 [TBL] [Abstract][Full Text] [Related]
12. Inhibition of mammalian squalene synthetase activity by zaragozic acid A is a result of competitive inhibition followed by mechanism-based irreversible inactivation. Lindsey S; Harwood HJ J Biol Chem; 1995 Apr; 270(16):9083-96. PubMed ID: 7721822 [TBL] [Abstract][Full Text] [Related]
13. Development of a radiometric spot-wash assay for squalene synthase. Tait RM Anal Biochem; 1992 Jun; 203(2):310-6. PubMed ID: 1416027 [TBL] [Abstract][Full Text] [Related]
14. Squalene synthetase. Solubilization and partial purification of squalene synthetase, copurification of presqualene pyrophosphate and squalene synthetase activities. Kuswik-Rabiega G; Rilling HC J Biol Chem; 1987 Feb; 262(4):1505-9. PubMed ID: 3805037 [TBL] [Abstract][Full Text] [Related]
15. 1-Hydroxy-3-(methylpentylamino)-propylidene-1,1-bisphosphonic acid as a potent inhibitor of squalene synthase. Amin D; Cornell SA; Perrone MH; Bilder GE Arzneimittelforschung; 1996 Aug; 46(8):759-62. PubMed ID: 9125274 [TBL] [Abstract][Full Text] [Related]
16. Lipophilic 1,1-bisphosphonates are potent squalene synthase inhibitors and orally active cholesterol lowering agents in vivo. Ciosek CP; Magnin DR; Harrity TW; Logan JV; Dickson JK; Gordon EM; Hamilton KA; Jolibois KG; Kunselman LK; Lawrence RM J Biol Chem; 1993 Nov; 268(33):24832-7. PubMed ID: 8227045 [TBL] [Abstract][Full Text] [Related]
18. Characterization of two distinct allyl pyrophosphatase activities from rat liver microsomes. Bansal VS; Vaidya S Arch Biochem Biophys; 1994 Dec; 315(2):393-9. PubMed ID: 7986083 [TBL] [Abstract][Full Text] [Related]
19. Synthesis of novel 4,1-benzoxazepine derivatives as squalene synthase inhibitors and their inhibition of cholesterol synthesis. Miki T; Kori M; Mabuchi H; Tozawa R; Nishimoto T; Sugiyama Y; Teshima K; Yukimasa H J Med Chem; 2002 Sep; 45(20):4571-80. PubMed ID: 12238936 [TBL] [Abstract][Full Text] [Related]
20. Amidinium cation as a mimic of allylic carbocation: synthesis and squalene synthetase inhibitory activity of an amidinium analog of a carbocation intermediate. Prashad M J Med Chem; 1993 Mar; 36(5):631-2. PubMed ID: 8496942 [No Abstract] [Full Text] [Related] [Next] [New Search]