BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

211 related articles for article (PubMed ID: 31721788)

  • 1. Omecamtiv mecarbil lowers the contractile deficit in a mouse model of nebulin-based nemaline myopathy.
    Lindqvist J; Lee EJ; Karimi E; Kolb J; Granzier H
    PLoS One; 2019; 14(11):e0224467. PubMed ID: 31721788
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of NEB pathogenic variants in patients reveals novel nemaline myopathy disease mechanisms and omecamtiv mecarbil force effects.
    Karimi E; Gohlke J; van der Borgh M; Lindqvist J; Hourani Z; Kolb J; Cossette S; Lawlor MW; Ottenheijm C; Granzier H
    Acta Neuropathol; 2024 Apr; 147(1):72. PubMed ID: 38634969
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nebulin deficiency in adult muscle causes sarcomere defects and muscle-type-dependent changes in trophicity: novel insights in nemaline myopathy.
    Li F; Buck D; De Winter J; Kolb J; Meng H; Birch C; Slater R; Escobar YN; Smith JE; Yang L; Konhilas J; Lawlor MW; Ottenheijm C; Granzier HL
    Hum Mol Genet; 2015 Sep; 24(18):5219-33. PubMed ID: 26123491
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Troponin activator augments muscle force in nemaline myopathy patients with nebulin mutations.
    de Winter JM; Buck D; Hidalgo C; Jasper JR; Malik FI; Clarke NF; Stienen GJ; Lawlor MW; Beggs AH; Ottenheijm CA; Granzier H
    J Med Genet; 2013 Jun; 50(6):383-92. PubMed ID: 23572184
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Deleting exon 55 from the nebulin gene induces severe muscle weakness in a mouse model for nemaline myopathy.
    Ottenheijm CA; Buck D; de Winter JM; Ferrara C; Piroddi N; Tesi C; Jasper JR; Malik FI; Meng H; Stienen GJ; Beggs AH; Labeit S; Poggesi C; Lawlor MW; Granzier H
    Brain; 2013 Jun; 136(Pt 6):1718-31. PubMed ID: 23715096
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional Characterization of the Intact Diaphragm in a Nebulin-Based Nemaline Myopathy (NM) Model-Effects of the Fast Skeletal Muscle Troponin Activator
    Lee EJ; Kolb J; Hwee DT; Malik FI; Granzier HL
    Int J Mol Sci; 2019 Oct; 20(20):. PubMed ID: 31658633
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Muscle weakness in respiratory and peripheral skeletal muscles in a mouse model for nebulin-based nemaline myopathy.
    Joureau B; de Winter JM; Stam K; Granzier H; Ottenheijm CA
    Neuromuscul Disord; 2017 Jan; 27(1):83-89. PubMed ID: 27890461
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vivo characterization of skeletal muscle function in nebulin-deficient mice.
    Gineste C; Ogier AC; Varlet I; Hourani Z; Bernard M; Granzier H; Bendahan D; Gondin J
    Muscle Nerve; 2020 Mar; 61(3):416-424. PubMed ID: 31893464
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Thin filament length dysregulation contributes to muscle weakness in nemaline myopathy patients with nebulin deficiency.
    Ottenheijm CA; Witt CC; Stienen GJ; Labeit S; Beggs AH; Granzier H
    Hum Mol Genet; 2009 Jul; 18(13):2359-69. PubMed ID: 19346529
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fast skeletal muscle troponin activation increases force of mouse fast skeletal muscle and ameliorates weakness due to nebulin-deficiency.
    Lee EJ; De Winter JM; Buck D; Jasper JR; Malik FI; Labeit S; Ottenheijm CA; Granzier H
    PLoS One; 2013; 8(2):e55861. PubMed ID: 23437068
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of levosimendan on the contractility of muscle fibers from nemaline myopathy patients with mutations in the nebulin gene.
    de Winter JM; Joureau B; Sequeira V; Clarke NF; van der Velden J; Stienen GJ; Granzier H; Beggs AH; Ottenheijm CA
    Skelet Muscle; 2015; 5():12. PubMed ID: 25949787
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of
    Karimi E; van der Borgh M; Lindqvist J; Gohlke J; Hourani Z; Kolb J; Cossette S; Lawlor MW; Ottenheijm C; Granzier H
    bioRxiv; 2023 Dec; ():. PubMed ID: 38187705
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expressing a Z-disk nebulin fragment in nebulin-deficient mouse muscle: effects on muscle structure and function.
    Li F; Kolb J; Crudele J; Tonino P; Hourani Z; Smith JE; Chamberlain JS; Granzier H
    Skelet Muscle; 2020 Jan; 10(1):2. PubMed ID: 31992366
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neb: a zebrafish model of nemaline myopathy due to nebulin mutation.
    Telfer WR; Nelson DD; Waugh T; Brooks SV; Dowling JJ
    Dis Model Mech; 2012 May; 5(3):389-96. PubMed ID: 22159874
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Altered myofilament function depresses force generation in patients with nebulin-based nemaline myopathy (NEM2).
    Ottenheijm CA; Hooijman P; DeChene ET; Stienen GJ; Beggs AH; Granzier H
    J Struct Biol; 2010 May; 170(2):334-43. PubMed ID: 19944167
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reduced thin filament length in nebulin-knockout skeletal muscle alters isometric contractile properties.
    Gokhin DS; Bang ML; Zhang J; Chen J; Lieber RL
    Am J Physiol Cell Physiol; 2009 May; 296(5):C1123-32. PubMed ID: 19295172
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nebulin alters cross-bridge cycling kinetics and increases thin filament activation: a novel mechanism for increasing tension and reducing tension cost.
    Chandra M; Mamidi R; Ford S; Hidalgo C; Witt C; Ottenheijm C; Labeit S; Granzier H
    J Biol Chem; 2009 Nov; 284(45):30889-96. PubMed ID: 19736309
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nebulin nemaline myopathy recapitulated in a compound heterozygous mouse model with both a missense and a nonsense mutation in Neb.
    Laitila JM; McNamara EL; Wingate CD; Goullee H; Ross JA; Taylor RL; van der Pijl R; Griffiths LM; Harries R; Ravenscroft G; Clayton JS; Sewry C; Lawlor MW; Ottenheijm CAC; Bakker AJ; Ochala J; Laing NG; Wallgren-Pettersson C; Pelin K; Nowak KJ
    Acta Neuropathol Commun; 2020 Feb; 8(1):18. PubMed ID: 32066503
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nebulin, a major player in muscle health and disease.
    Labeit S; Ottenheijm CA; Granzier H
    FASEB J; 2011 Mar; 25(3):822-9. PubMed ID: 21115852
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Changes in cross-bridge cycling underlie muscle weakness in patients with tropomyosin 3-based myopathy.
    Ottenheijm CA; Lawlor MW; Stienen GJ; Granzier H; Beggs AH
    Hum Mol Genet; 2011 May; 20(10):2015-25. PubMed ID: 21357678
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.