179 related articles for article (PubMed ID: 31727359)
21. An assessment of pharmacokinetics and antioxidant activity of free silymarin flavonolignans in healthy volunteers: a dose escalation study.
Zhu HJ; Brinda BJ; Chavin KD; Bernstein HJ; Patrick KS; Markowitz JS
Drug Metab Dispos; 2013 Sep; 41(9):1679-85. PubMed ID: 23835761
[TBL] [Abstract][Full Text] [Related]
22. Aldosterone glucuronidation by human liver and kidney microsomes and recombinant UDP-glucuronosyltransferases: inhibition by NSAIDs.
Knights KM; Winner LK; Elliot DJ; Bowalgaha K; Miners JO
Br J Clin Pharmacol; 2009 Sep; 68(3):402-12. PubMed ID: 19740398
[TBL] [Abstract][Full Text] [Related]
23. Glucuronidation of nonsteroidal anti-inflammatory drugs: identifying the enzymes responsible in human liver microsomes.
Kuehl GE; Lampe JW; Potter JD; Bigler J
Drug Metab Dispos; 2005 Jul; 33(7):1027-35. PubMed ID: 15843492
[TBL] [Abstract][Full Text] [Related]
24. Cabozantinib Carries the Risk of Drug-Drug Interactions
Wang Z; Jiang L; Wang X; Yin H; Wang Z; Lv X; Liu Y
Curr Drug Metab; 2022; 23(11):912-919. PubMed ID: 36306450
[TBL] [Abstract][Full Text] [Related]
25. Two flavonolignans from milk thistle (Silybum marianum) inhibit CYP2C9-mediated warfarin metabolism at clinically achievable concentrations.
Brantley SJ; Oberlies NH; Kroll DJ; Paine MF
J Pharmacol Exp Ther; 2010 Mar; 332(3):1081-7. PubMed ID: 19934397
[TBL] [Abstract][Full Text] [Related]
26. Characterizations of Human UDP-Glucuronosyltransferase Enzymes in the Conjugation of p-Cresol.
Rong Y; Kiang TKL
Toxicol Sci; 2020 Aug; 176(2):285-296. PubMed ID: 32421801
[TBL] [Abstract][Full Text] [Related]
27. Characterization of dibenzo[a,l]pyrene-trans-11,12-diol (dibenzo[def,p]chrysene) glucuronidation by UDP-glucuronosyltransferases.
Olson KC; Sun D; Chen G; Sharma AK; Amin S; Ropson IJ; Spratt TE; Lazarus P
Chem Res Toxicol; 2011 Sep; 24(9):1549-59. PubMed ID: 21780761
[TBL] [Abstract][Full Text] [Related]
28. Uridine diphosphate glucuronosyltransferase isoform-dependent regiospecificity of glucuronidation of flavonoids.
Singh R; Wu B; Tang L; Hu M
J Agric Food Chem; 2011 Jul; 59(13):7452-64. PubMed ID: 21413806
[TBL] [Abstract][Full Text] [Related]
29. Accumulation of silymarin in milk thistle seeds under drought stress.
Keshavarz Afshar R; Chaichi MR; Ansari Jovini M; Jahanzad E; Hashemi M
Planta; 2015 Sep; 242(3):539-43. PubMed ID: 25708739
[TBL] [Abstract][Full Text] [Related]
30. Glucuronidation of DRF-6574, hydroxy metabolite of DRF-4367 (a novel COX-2 inhibitor) by pooled human liver, intestinal microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT1A1, 1A3 and 1A8.
Muzeeb S; Basha SJ; Shashikumar D; Mullangi R; Srinivas NR
Eur J Drug Metab Pharmacokinet; 2006; 31(4):299-309. PubMed ID: 17315542
[TBL] [Abstract][Full Text] [Related]
31. Optimized methods for targeted peptide-based quantification of human uridine 5'-diphosphate-glucuronosyltransferases in biological specimens using liquid chromatography-tandem mass spectrometry.
Sato Y; Nagata M; Tetsuka K; Tamura K; Miyashita A; Kawamura A; Usui T
Drug Metab Dispos; 2014 May; 42(5):885-9. PubMed ID: 24595681
[TBL] [Abstract][Full Text] [Related]
32. Human liver UDP-glucuronosyltransferase isoforms involved in the glucuronidation of 7-ethyl-10-hydroxycamptothecin.
Hanioka N; Ozawa S; Jinno H; Ando M; Saito Y; Sawada J
Xenobiotica; 2001 Oct; 31(10):687-99. PubMed ID: 11695848
[TBL] [Abstract][Full Text] [Related]
33. Identification and characterization of human UDP-glucuronosyltransferases responsible for the in-vitro glucuronidation of arctigenin.
Xin H; Xia YL; Hou J; Wang P; He W; Yang L; Ge GB; Xu W
J Pharm Pharmacol; 2015 Dec; 67(12):1673-81. PubMed ID: 26407805
[TBL] [Abstract][Full Text] [Related]
34. Renal drug metabolism in humans: the potential for drug-endobiotic interactions involving cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT).
Knights KM; Rowland A; Miners JO
Br J Clin Pharmacol; 2013 Oct; 76(4):587-602. PubMed ID: 23362865
[TBL] [Abstract][Full Text] [Related]
35. Characterization of hepatic and intestinal glucuronidation of magnolol: application of the relative activity factor approach to decipher the contributions of multiple UDP-glucuronosyltransferase isoforms.
Zhu L; Ge G; Zhang H; Liu H; He G; Liang S; Zhang Y; Fang Z; Dong P; Finel M; Yang L
Drug Metab Dispos; 2012 Mar; 40(3):529-38. PubMed ID: 22180045
[TBL] [Abstract][Full Text] [Related]
36. Metabolism of 1'- and 4-hydroxymidazolam by glucuronide conjugation is largely mediated by UDP-glucuronosyltransferases 1A4, 2B4, and 2B7.
Seo KA; Bae SK; Choi YK; Choi CS; Liu KH; Shin JG
Drug Metab Dispos; 2010 Nov; 38(11):2007-13. PubMed ID: 20713656
[TBL] [Abstract][Full Text] [Related]
37. Acyl glucuronidation of fluoroquinolone antibiotics by the UDP-glucuronosyltransferase 1A subfamily in human liver microsomes.
Tachibana M; Tanaka M; Masubuchi Y; Horie T
Drug Metab Dispos; 2005 Jun; 33(6):803-11. PubMed ID: 15769885
[TBL] [Abstract][Full Text] [Related]
38. Semisynthesis, cytotoxicity, antiviral activity, and drug interaction liability of 7-O-methylated analogues of flavonolignans from milk thistle.
Althagafy HS; Graf TN; Sy-Cordero AA; Gufford BT; Paine MF; Wagoner J; Polyak SJ; Croatt MP; Oberlies NH
Bioorg Med Chem; 2013 Jul; 21(13):3919-26. PubMed ID: 23673225
[TBL] [Abstract][Full Text] [Related]
39. A high throughput assay for the glucuronidation of 7-hydroxy-4-trifluoromethylcoumarin by recombinant human UDP-glucuronosyltransferases and liver microsomes.
Rahikainen T; Häkkinen MR; Finel M; Pasanen M; Juvonen RO
Xenobiotica; 2013 Oct; 43(10):853-61. PubMed ID: 23551063
[TBL] [Abstract][Full Text] [Related]
40. Flavonolignans from Aspergillus iizukae, a fungal endophyte of milk thistle (Silybum marianum).
El-Elimat T; Raja HA; Graf TN; Faeth SH; Cech NB; Oberlies NH
J Nat Prod; 2014 Feb; 77(2):193-9. PubMed ID: 24456525
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
