These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

360 related articles for article (PubMed ID: 31727771)

  • 1. The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis.
    Oser MG; Sabet AH; Gao W; Chakraborty AA; Schinzel AC; Jennings RB; Fonseca R; Bonal DM; Booker MA; Flaifel A; Novak JS; Christensen CL; Zhang H; Herbert ZT; Tolstorukov MY; Buss EJ; Wong KK; Bronson RT; Nguyen QD; Signoretti S; Kaelin WG
    Genes Dev; 2019 Dec; 33(23-24):1718-1738. PubMed ID: 31727771
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition.
    Augert A; Eastwood E; Ibrahim AH; Wu N; Grunblatt E; Basom R; Liggitt D; Eaton KD; Martins R; Poirier JT; Rudin CM; Milletti F; Cheng WY; Mack F; MacPherson D
    Sci Signal; 2019 Feb; 12(567):. PubMed ID: 30723171
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Increased mitochondrial function downstream from KDM5A histone demethylase rescues differentiation in pRB-deficient cells.
    Váraljai R; Islam AB; Beshiri ML; Rehman J; Lopez-Bigas N; Benevolenskaya EV
    Genes Dev; 2015 Sep; 29(17):1817-34. PubMed ID: 26314709
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas.
    Meder L; König K; Ozretić L; Schultheis AM; Ueckeroth F; Ade CP; Albus K; Boehm D; Rommerscheidt-Fuss U; Florin A; Buhl T; Hartmann W; Wolf J; Merkelbach-Bruse S; Eilers M; Perner S; Heukamp LC; Buettner R
    Int J Cancer; 2016 Feb; 138(4):927-38. PubMed ID: 26340530
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ascl1-induced Wnt11 regulates neuroendocrine differentiation, cell proliferation, and E-cadherin expression in small-cell lung cancer and Wnt11 regulates small-cell lung cancer biology.
    Tenjin Y; Kudoh S; Kubota S; Yamada T; Matsuo A; Sato Y; Ichimura T; Kohrogi H; Sashida G; Sakagami T; Ito T
    Lab Invest; 2019 Nov; 99(11):1622-1635. PubMed ID: 31231131
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular pathology of small cell lung cancer: Overview from studies on neuroendocrine differentiation regulated by ASCL1 and Notch signaling.
    Ito T
    Pathol Int; 2024 May; 74(5):239-251. PubMed ID: 38607250
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ASCL1 represses a SOX9
    Olsen RR; Ireland AS; Kastner DW; Groves SM; Spainhower KB; Pozo K; Kelenis DP; Whitney CP; Guthrie MR; Wait SJ; Soltero D; Witt BL; Quaranta V; Johnson JE; Oliver TG
    Genes Dev; 2021 Jun; 35(11-12):847-869. PubMed ID: 34016693
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Taking SCLC on a Bad LSD(1) Trip One NOTCH Further.
    Kim J; Sage J
    Trends Mol Med; 2019 Apr; 25(4):261-264. PubMed ID: 30852141
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Small cell lung cancer, an epithelial to mesenchymal transition (EMT)-like cancer: significance of inactive Notch signaling and expression of achaete-scute complex homologue 1.
    Ito T; Kudoh S; Ichimura T; Fujino K; Hassan WA; Udaka N
    Hum Cell; 2017 Jan; 30(1):1-10. PubMed ID: 27785690
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Plasticity in the Absence of NOTCH Uncovers a RUNX2-Dependent Pathway in Small Cell Lung Cancer.
    Hong D; Knelson EH; Li Y; Durmaz YT; Gao W; Walton E; Vajdi A; Thai T; Sticco-Ivins M; Sabet AH; Jones KL; Schinzel AC; Bronson RT; Nguyen QD; Tolstorukov MY; Vivero M; Signoretti S; Barbie DA; Oser MG
    Cancer Res; 2022 Jan; 82(2):248-263. PubMed ID: 34810201
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Autochthonous tumors driven by
    McBrayer SK; Olenchock BA; DiNatale GJ; Shi DD; Khanal J; Jennings RB; Novak JS; Oser MG; Robbins AK; Modiste R; Bonal D; Moslehi J; Bronson RT; Neuberg D; Nguyen QD; Signoretti S; Losman JA; Kaelin WG
    Proc Natl Acad Sci U S A; 2018 Apr; 115(16):E3741-E3748. PubMed ID: 29610306
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Histone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complex.
    Liefke R; Oswald F; Alvarado C; Ferres-Marco D; Mittler G; Rodriguez P; Dominguez M; Borggrefe T
    Genes Dev; 2010 Mar; 24(6):590-601. PubMed ID: 20231316
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance.
    Gale M; Sayegh J; Cao J; Norcia M; Gareiss P; Hoyer D; Merkel JS; Yan Q
    Oncotarget; 2016 Jun; 7(26):39931-39944. PubMed ID: 27224921
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Insulinoma-Associated Protein 1 Is a Crucial Regulator of Neuroendocrine Differentiation in Lung Cancer.
    Fujino K; Motooka Y; Hassan WA; Ali Abdalla MO; Sato Y; Kudoh S; Hasegawa K; Niimori-Kita K; Kobayashi H; Kubota I; Wakimoto J; Suzuki M; Ito T
    Am J Pathol; 2015 Dec; 185(12):3164-77. PubMed ID: 26482608
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Physical and functional interactions between the histone H3K4 demethylase KDM5A and the nucleosome remodeling and deacetylase (NuRD) complex.
    Nishibuchi G; Shibata Y; Hayakawa T; Hayakawa N; Ohtani Y; Sinmyozu K; Tagami H; Nakayama J
    J Biol Chem; 2014 Oct; 289(42):28956-70. PubMed ID: 25190814
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis.
    Yoo J; Kim GW; Jeon YH; Kim JY; Lee SW; Kwon SH
    Exp Mol Med; 2022 Dec; 54(12):2107-2117. PubMed ID: 36509829
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1.
    Lin W; Cao J; Liu J; Beshiri ML; Fujiwara Y; Francis J; Cherniack AD; Geisen C; Blair LP; Zou MR; Shen X; Kawamori D; Liu Z; Grisanzio C; Watanabe H; Minamishima YA; Zhang Q; Kulkarni RN; Signoretti S; Rodig SJ; Bronson RT; Orkin SH; Tuck DP; Benevolenskaya EV; Meyerson M; Kaelin WG; Yan Q
    Proc Natl Acad Sci U S A; 2011 Aug; 108(33):13379-86. PubMed ID: 21788502
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of neuroendocrine plasticity by the RNA-binding protein ZFP36L1.
    Chen HY; Durmaz YT; Li Y; Sabet AH; Vajdi A; Denize T; Walton E; Laimon YN; Doench JG; Mahadevan NR; Losman JA; Barbie DA; Tolstorukov MY; Rudin CM; Sen T; Signoretti S; Oser MG
    Nat Commun; 2022 Aug; 13(1):4998. PubMed ID: 36008402
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ASCL1 and NEUROD1 Reveal Heterogeneity in Pulmonary Neuroendocrine Tumors and Regulate Distinct Genetic Programs.
    Borromeo MD; Savage TK; Kollipara RK; He M; Augustyn A; Osborne JK; Girard L; Minna JD; Gazdar AF; Cobb MH; Johnson JE
    Cell Rep; 2016 Aug; 16(5):1259-1272. PubMed ID: 27452466
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The emerging role of KDM5A in human cancer.
    Yang GJ; Zhu MH; Lu XJ; Liu YJ; Lu JF; Leung CH; Ma DL; Chen J
    J Hematol Oncol; 2021 Feb; 14(1):30. PubMed ID: 33596982
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.