These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

288 related articles for article (PubMed ID: 31728578)

  • 1. Molecular mechanisms of topoisomerase 2 DNA-protein crosslink resolution.
    Riccio AA; Schellenberg MJ; Williams RS
    Cell Mol Life Sci; 2020 Jan; 77(1):81-91. PubMed ID: 31728578
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effect of TDP2 on the Level of TOP2-DNA Complexes and SUMOylated TOP2-DNA Complexes.
    Lee KC; Swan RL; Sondka Z; Padget K; Cowell IG; Austin CA
    Int J Mol Sci; 2018 Jul; 19(7):. PubMed ID: 30011940
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ZATT (ZNF451)-mediated resolution of topoisomerase 2 DNA-protein cross-links.
    Schellenberg MJ; Lieberman JA; Herrero-Ruiz A; Butler LR; Williams JG; Muñoz-Cabello AM; Mueller GA; London RE; Cortés-Ledesma F; Williams RS
    Science; 2017 Sep; 357(6358):1412-1416. PubMed ID: 28912134
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcription.
    Gómez-Herreros F; Zagnoli-Vieira G; Ntai I; Martínez-Macías MI; Anderson RM; Herrero-Ruíz A; Caldecott KW
    Nat Commun; 2017 Aug; 8(1):233. PubMed ID: 28794467
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo.
    Gómez-Herreros F; Romero-Granados R; Zeng Z; Alvarez-Quilón A; Quintero C; Ju L; Umans L; Vermeire L; Huylebroeck D; Caldecott KW; Cortés-Ledesma F
    PLoS Genet; 2013; 9(3):e1003226. PubMed ID: 23505375
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Depletion of tyrosyl DNA phosphodiesterase 2 activity enhances etoposide-mediated double-strand break formation and cell killing.
    Kont YS; Dutta A; Mallisetty A; Mathew J; Minas T; Kraus C; Dhopeshwarkar P; Kallakury B; Mitra S; Üren A; Adhikari S
    DNA Repair (Amst); 2016 Jul; 43():38-47. PubMed ID: 27235629
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Proteolytic degradation of topoisomerase II (Top2) enables the processing of Top2·DNA and Top2·RNA covalent complexes by tyrosyl-DNA-phosphodiesterase 2 (TDP2).
    Gao R; Schellenberg MJ; Huang SY; Abdelmalak M; Marchand C; Nitiss KC; Nitiss JL; Williams RS; Pommier Y
    J Biol Chem; 2014 Jun; 289(26):17960-9. PubMed ID: 24808172
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genome-Wide CRISPR Screens Reveal ZATT as a Synthetic Lethal Target of TOP2-Poison Etoposide That Can Act in a TDP2-Independent Pathway.
    Park JM; Zhang H; Nie L; Wang C; Huang M; Feng X; Tang M; Chen Z; Xiong Y; Lee N; Li S; Yin L; Hart T; Chen J
    Int J Mol Sci; 2023 Mar; 24(7):. PubMed ID: 37047518
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Type II DNA Topoisomerases Cause Spontaneous Double-Strand Breaks in Genomic DNA.
    Morimoto S; Tsuda M; Bunch H; Sasanuma H; Austin C; Takeda S
    Genes (Basel); 2019 Oct; 10(11):. PubMed ID: 31671674
    [TBL] [Abstract][Full Text] [Related]  

  • 10. From the TOP: Formation, recognition and resolution of topoisomerase DNA protein crosslinks.
    Wojtaszek JL; Williams RS
    DNA Repair (Amst); 2024 Oct; 142():103751. PubMed ID: 39180935
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanisms to Repair Stalled Topoisomerase II-DNA Covalent Complexes.
    Swan RL; Cowell IG; Austin CA
    Mol Pharmacol; 2022 Jan; 101(1):24-32. PubMed ID: 34689119
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Suppressing proteasome mediated processing of topoisomerase II DNA-protein complexes preserves genome integrity.
    Sciascia N; Wu W; Zong D; Sun Y; Wong N; John S; Wangsa D; Ried T; Bunting SF; Pommier Y; Nussenzweig A
    Elife; 2020 Feb; 9():. PubMed ID: 32057297
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of topoisomerase II stability and activity by ubiquitination and SUMOylation: clinical implications for cancer chemotherapy.
    Ma Y; North BJ; Shu J
    Mol Biol Rep; 2021 Sep; 48(9):6589-6601. PubMed ID: 34476738
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
    Schellenberg MJ; Perera L; Strom CN; Waters CA; Monian B; Appel CD; Vilas CK; Williams JG; Ramsden DA; Williams RS
    Nucleic Acids Res; 2016 May; 44(8):3829-44. PubMed ID: 27060144
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RAD54L2 counters TOP2-DNA adducts to promote genome stability.
    D'Alessandro G; Morales-Juarez DA; Richards SL; Nitiss KC; Serrano-Benitez A; Wang J; Thomas JC; Gupta V; Voigt A; Belotserkovskaya R; Goh CG; Bowden AR; Galanty Y; Beli P; Nitiss JL; Zagnoli-Vieira G; Jackson SP
    Sci Adv; 2023 Dec; 9(49):eadl2108. PubMed ID: 38055822
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Untangling trapped topoisomerases with tyrosyl-DNA phosphodiesterases.
    Zagnoli-Vieira G; Caldecott KW
    DNA Repair (Amst); 2020 Oct; 94():102900. PubMed ID: 32653827
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Small Molecule Inhibitors Confirm Ubiquitin-Dependent Removal of TOP2-DNA Covalent Complexes.
    Swan RL; Poh LLK; Cowell IG; Austin CA
    Mol Pharmacol; 2020 Sep; 98(3):222-233. PubMed ID: 32587095
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RAD54L2-mediated DNA damage avoidance pathway specifically preserves genome integrity in response to topoisomerase 2 poisons.
    Zhang H; Xiong Y; Sun Y; Park JM; Su D; Feng X; Keast S; Tang M; Huang M; Wang C; Srivastava M; Yang C; Zhu D; Chen Z; Li S; Yin L; Pommier Y; Chen J
    Sci Adv; 2023 Dec; 9(49):eadi6681. PubMed ID: 38055811
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Introduction to the multi-author-review: emerging advances in the structural chemistry of DNA strand break repair.
    Williams RS
    Cell Mol Life Sci; 2020 Jan; 77(1):1-2. PubMed ID: 31712993
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TDP2, TOP2, and SUMO: what is ZATT about?
    Zagnoli-Vieira G; Caldecott KW
    Cell Res; 2017 Dec; 27(12):1405-1406. PubMed ID: 29160298
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.