BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 31732616)

  • 1. The YAP1 Signaling Inhibitors, Verteporfin and CA3, Suppress the Mesothelioma Cancer Stem Cell Phenotype.
    Kandasamy S; Adhikary G; Rorke EA; Friedberg JS; Mickle MB; Alexander HR; Eckert RL
    Mol Cancer Res; 2020 Mar; 18(3):343-351. PubMed ID: 31732616
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Verteporfin targeting YAP1/TAZ-TEAD transcriptional activity inhibits the tumorigenic properties of gastric cancer stem cells.
    Giraud J; Molina-Castro S; Seeneevassen L; Sifré E; Izotte J; Tiffon C; Staedel C; Boeuf H; Fernandez S; Barthelemy P; Megraud F; Lehours P; Dubus P; Varon C
    Int J Cancer; 2020 Apr; 146(8):2255-2267. PubMed ID: 31489619
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mesothelioma cancer cells are glutamine addicted and glutamine restriction reduces YAP1 signaling to attenuate tumor formation.
    Adhikary G; Shrestha S; Naselsky W; Newland JJ; Chen X; Xu W; Emadi A; Friedberg JS; Eckert RL
    Mol Carcinog; 2023 Apr; 62(4):438-449. PubMed ID: 36562471
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting YAP in malignant pleural mesothelioma.
    Zhang WQ; Dai YY; Hsu PC; Wang H; Cheng L; Yang YL; Wang YC; Xu ZD; Liu S; Chan G; Hu B; Li H; Jablons DM; You L
    J Cell Mol Med; 2017 Nov; 21(11):2663-2676. PubMed ID: 28470935
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of YAP function overcomes BRAF inhibitor resistance in melanoma cancer stem cells.
    Fisher ML; Grun D; Adhikary G; Xu W; Eckert RL
    Oncotarget; 2017 Dec; 8(66):110257-110272. PubMed ID: 29299145
    [TBL] [Abstract][Full Text] [Related]  

  • 6. YAP/TAZ Transcriptional Coactivators Create Therapeutic Vulnerability to Verteporfin in EGFR-mutant Glioblastoma.
    Vigneswaran K; Boyd NH; Oh SY; Lallani S; Boucher A; Neill SG; Olson JJ; Read RD
    Clin Cancer Res; 2021 Mar; 27(5):1553-1569. PubMed ID: 33172899
    [TBL] [Abstract][Full Text] [Related]  

  • 7. VGLL4 inhibits YAP1/TEAD signaling to suppress the epidermal squamous cell carcinoma cancer phenotype.
    Mickle M; Adhikary G; Shrestha S; Xu W; Eckert RL
    Mol Carcinog; 2021 Jul; 60(7):497-507. PubMed ID: 34004031
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular Features of the YAP Inhibitor Verteporfin: Synthesis of Hexasubstituted Dipyrrins as Potential Inhibitors of YAP/TAZ, the Downstream Effectors of the Hippo Pathway.
    Gibault F; Bailly F; Corvaisier M; Coevoet M; Huet G; Melnyk P; Cotelle P
    ChemMedChem; 2017 Jun; 12(12):954-961. PubMed ID: 28334506
    [TBL] [Abstract][Full Text] [Related]  

  • 9. FGF18-FGFR2 signaling triggers the activation of c-Jun-YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential.
    Zhang J; Wong CC; Leung KT; Wu F; Zhou Y; Tong JHM; Chan RCK; Li H; Wang Y; Yan H; Liu L; Wu WKK; Chan MWY; Cheng ASL; Yu J; Wong N; Lo KW; To KF; Kang W
    Oncogene; 2020 Oct; 39(43):6647-6663. PubMed ID: 32934314
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1.
    Zhang H; Ramakrishnan SK; Triner D; Centofanti B; Maitra D; Győrffy B; Sebolt-Leopold JS; Dame MK; Varani J; Brenner DE; Fearon ER; Omary MB; Shah YM
    Sci Signal; 2015 Oct; 8(397):ra98. PubMed ID: 26443705
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting Hippo coactivator YAP1 through BET bromodomain inhibition in esophageal adenocarcinoma.
    Song S; Li Y; Xu Y; Ma L; Pool Pizzi M; Jin J; Scott AW; Huo L; Wang Y; Lee JH; Bhutani MS; Weston B; Shanbhag ND; Johnson RL; Ajani JA
    Mol Oncol; 2020 Jun; 14(6):1410-1426. PubMed ID: 32175692
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Verteporfin induces apoptosis and reduces the stem cell-like properties in Neuroblastoma tumour-initiating cells through inhibition of the YAP/TAZ pathway.
    Fusco P; Mattiuzzo E; Frasson C; Viola G; Cimetta E; Esposito MR; Tonini GP
    Eur J Pharmacol; 2021 Feb; 893():173829. PubMed ID: 33347823
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer.
    Nimmakayala RK; Ogunleye AO; Parte S; Krishna Kumar N; Raut P; Varadharaj V; Perumal NK; Nallasamy P; Rauth S; Cox JL; Lele SM; Batra SK; Ponnusamy MP
    Cell Death Dis; 2022 Oct; 13(10):839. PubMed ID: 36180487
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Doublecortin-like kinase 1 activates Hippo pathway to promote migration, invasion and proliferation of pancreatic cancer cells].
    Yan R; Liang ZW; Liu HS; Ge Y; An GY
    Zhonghua Zhong Liu Za Zhi; 2023 Jul; 45(7):594-604. PubMed ID: 37462016
    [No Abstract]   [Full Text] [Related]  

  • 15. TEAD Inhibition Overcomes YAP1/TAZ-Driven Primary and Acquired Resistance to KRASG12C Inhibitors.
    Edwards AC; Stalnecker CA; Jean Morales A; Taylor KE; Klomp JE; Klomp JA; Waters AM; Sudhakar N; Hallin J; Tang TT; Olson P; Post L; Christensen JG; Cox AD; Der CJ
    Cancer Res; 2023 Dec; 83(24):4112-4129. PubMed ID: 37934103
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SS18-SSX-Dependent YAP/TAZ Signaling in Synovial Sarcoma.
    Isfort I; Cyra M; Elges S; Kailayangiri S; Altvater B; Rossig C; Steinestel K; Grünewald I; Huss S; Eßeling E; Mikesch JH; Hafner S; Simmet T; Wozniak A; Schöffski P; Larsson O; Wardelmann E; Trautmann M; Hartmann W
    Clin Cancer Res; 2019 Jun; 25(12):3718-3731. PubMed ID: 30814111
    [TBL] [Abstract][Full Text] [Related]  

  • 17. YAP1 is essential for malignant mesothelioma tumor maintenance.
    Calvet L; Dos-Santos O; Spanakis E; Jean-Baptiste V; Le Bail JC; Buzy A; Paul P; Henry C; Valence S; Dib C; Pollard J; Sidhu S; Moll J; Debussche L; Valtingojer I
    BMC Cancer; 2022 Jun; 22(1):639. PubMed ID: 35689194
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models.
    Hillen H; Candi A; Vanderhoydonck B; Kowalczyk W; Sansores-Garcia L; Kesikiadou EC; Van Huffel L; Spiessens L; Nijs M; Soons E; Haeck W; Klaassen H; Smets W; Spieser SA; Marchand A; Chaltin P; Ciesielski F; Debaene F; Chen L; Kamal A; Gwaltney SL; Versele M; Halder GA
    Mol Cancer Ther; 2024 Jan; 23(1):3-13. PubMed ID: 37748190
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting the YAP/TAZ Pathway in Uveal and Conjunctival Melanoma With Verteporfin.
    Brouwer NJ; Konstantinou EK; Gragoudas ES; Marinkovic M; Luyten GPM; Kim IK; Jager MJ; Vavvas DG
    Invest Ophthalmol Vis Sci; 2021 Apr; 62(4):3. PubMed ID: 33798262
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Statin suppresses Hippo pathway-inactivated malignant mesothelioma cells and blocks the YAP/CD44 growth stimulatory axis.
    Tanaka K; Osada H; Murakami-Tonami Y; Horio Y; Hida T; Sekido Y
    Cancer Lett; 2017 Jan; 385():215-224. PubMed ID: 27773750
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.