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6. The mechanism of prevention of paracetamol-induced hepatotoxicity by 3,5-dialkyl substitution. The roles of glutathione depletion and oxidative stress. van de Straat R; de Vries J; Debets AJ; Vermeulen NP Biochem Pharmacol; 1987 Jul; 36(13):2065-70. PubMed ID: 3606627 [TBL] [Abstract][Full Text] [Related]
7. Reactions of N-acetyl-p-benzoquinone imine with reduced glutathione, acetaminophen, and NADPH. Potter DW; Hinson JA Mol Pharmacol; 1986 Jul; 30(1):33-41. PubMed ID: 3724743 [TBL] [Abstract][Full Text] [Related]
8. Protein and nonprotein cysteinyl thiol modification by N-acetyl-p-benzoquinone imine via a novel ipso adduct. Chen W; Shockcor JP; Tonge R; Hunter A; Gartner C; Nelson SD Biochemistry; 1999 Jun; 38(25):8159-66. PubMed ID: 10387061 [TBL] [Abstract][Full Text] [Related]
9. The killing of cultured hepatocytes by N-acetyl-p-benzoquinone imine (NAPQI) as a model of the cytotoxicity of acetaminophen. Harman AW; Kyle ME; Serroni A; Farber JL Biochem Pharmacol; 1991 Apr; 41(8):1111-7. PubMed ID: 2009090 [TBL] [Abstract][Full Text] [Related]
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11. N-acetyl-p-benzoquinone imine-induced protein thiol modification in isolated rat hepatocytes. Weis M; Morgenstern R; Cotgreave IA; Nelson SD; Moldéus P Biochem Pharmacol; 1992 Apr; 43(7):1493-505. PubMed ID: 1567474 [TBL] [Abstract][Full Text] [Related]
12. Role of metabolism and oxidation-reduction cycling in the cytotoxicity of antitumor quinoneimines and quinonediimines. Powis G; Hodnett EM; Santone KS; See KL; Melder DC Cancer Res; 1987 May; 47(9):2363-70. PubMed ID: 3032421 [TBL] [Abstract][Full Text] [Related]
13. Investigation of mechanisms of acetaminophen toxicity in isolated rat hepatocytes with the acetaminophen analogues 3,5-dimethylacetaminophen and 2,6-dimethylacetaminophen. Porubek DJ; Rundgren M; Harvison PJ; Nelson SD; Moldéus P Mol Pharmacol; 1987 Jun; 31(6):647-53. PubMed ID: 3600610 [TBL] [Abstract][Full Text] [Related]
14. Cytotoxic effects of N-acetyl-p-benzoquinone imine, a common arylating intermediate of paracetamol and N-hydroxyparacetamol. Holme JA; Dahlin DC; Nelson SD; Dybing E Biochem Pharmacol; 1984 Feb; 33(3):401-6. PubMed ID: 6704159 [TBL] [Abstract][Full Text] [Related]
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17. N-acetyl-p-benzoquinone imine-induced changes in the energy metabolism in hepatocytes. Andersson BS; Rundgren M; Nelson SD; Harder S Chem Biol Interact; 1990; 75(2):201-11. PubMed ID: 2369786 [TBL] [Abstract][Full Text] [Related]
18. The toxicity of acetaminophen and N-acetyl-p-benzoquinone imine in isolated hepatocytes is associated with thiol depletion and increased cytosolic Ca2+. Moore M; Thor H; Moore G; Nelson S; Moldéus P; Orrenius S J Biol Chem; 1985 Oct; 260(24):13035-40. PubMed ID: 2932433 [TBL] [Abstract][Full Text] [Related]
19. Quinone imine-induced Ca2+ release from isolated rat liver mitochondria. Weis M; Moore GA; Cotgreave IA; Nelson SD; Moldeus P Chem Biol Interact; 1990; 76(2):227-40. PubMed ID: 2225230 [TBL] [Abstract][Full Text] [Related]
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