135 related articles for article (PubMed ID: 31734832)
21. A phase I trial of PR-104, a nitrogen mustard prodrug activated by both hypoxia and aldo-keto reductase 1C3, in patients with solid tumors.
Jameson MB; Rischin D; Pegram M; Gutheil J; Patterson AV; Denny WA; Wilson WR
Cancer Chemother Pharmacol; 2010 Mar; 65(4):791-801. PubMed ID: 20012293
[TBL] [Abstract][Full Text] [Related]
22. Phase 1 study of the MDM2 inhibitor AMG 232 in patients with advanced P53 wild-type solid tumors or multiple myeloma.
Gluck WL; Gounder MM; Frank R; Eskens F; Blay JY; Cassier PA; Soria JC; Chawla S; de Weger V; Wagner AJ; Siegel D; De Vos F; Rasmussen E; Henary HA
Invest New Drugs; 2020 Jun; 38(3):831-843. PubMed ID: 31359240
[TBL] [Abstract][Full Text] [Related]
23. Effect of the MDM2 antagonist RG7112 on the P53 pathway in patients with MDM2-amplified, well-differentiated or dedifferentiated liposarcoma: an exploratory proof-of-mechanism study.
Ray-Coquard I; Blay JY; Italiano A; Le Cesne A; Penel N; Zhi J; Heil F; Rueger R; Graves B; Ding M; Geho D; Middleton SA; Vassilev LT; Nichols GL; Bui BN
Lancet Oncol; 2012 Nov; 13(11):1133-40. PubMed ID: 23084521
[TBL] [Abstract][Full Text] [Related]
24. Phase I Trial of the Human Double Minute 2 Inhibitor MK-8242 in Patients With Advanced Solid Tumors.
Wagner AJ; Banerji U; Mahipal A; Somaiah N; Hirsch H; Fancourt C; Johnson-Levonas AO; Lam R; Meister AK; Russo G; Knox CD; Rose S; Hong DS
J Clin Oncol; 2017 Apr; 35(12):1304-1311. PubMed ID: 28240971
[TBL] [Abstract][Full Text] [Related]
25. The MDM2 antagonist idasanutlin in patients with polycythemia vera: results from a single-arm phase 2 study.
Mascarenhas J; Passamonti F; Burbury K; El-Galaly TC; Gerds A; Gupta V; Higgins B; Wonde K; Jamois C; Kovic B; Huw LY; Katakam S; Maffioli M; Mesa R; Palmer J; Bellini M; Ross DM; Vannucchi AM; Yacoub A
Blood Adv; 2022 Feb; 6(4):1162-1174. PubMed ID: 34933330
[TBL] [Abstract][Full Text] [Related]
26. Phase I dose escalation study of NMS-1286937, an orally available Polo-Like Kinase 1 inhibitor, in patients with advanced or metastatic solid tumors.
Weiss GJ; Jameson G; Von Hoff DD; Valsasina B; Davite C; Di Giulio C; Fiorentini F; Alzani R; Carpinelli P; Di Sanzo A; Galvani A; Isacchi A; Ramanathan RK
Invest New Drugs; 2018 Feb; 36(1):85-95. PubMed ID: 28726132
[TBL] [Abstract][Full Text] [Related]
27. First-in-man dose escalation and pharmacokinetic study of CAP7.1, a novel prodrug of etoposide, in adults with refractory solid tumours.
Keilholz U; Rohde L; Mehlitz P; Knoedler M; Schmittel A; Kümmerlen V; Klinghammer K; Treasure P; Lassus M; Steventon G; Machacek M; Utku N
Eur J Cancer; 2017 Jul; 80():14-25. PubMed ID: 28531881
[TBL] [Abstract][Full Text] [Related]
28. Phase I trial of continuous infusion 9-aminocamptothecin in patients with advanced solid tumors: 21-day infusion is an active well-tolerated regimen.
Sewak S; Sorich J; O'Leary J
Anticancer Drugs; 2006 Jun; 17(5):571-9. PubMed ID: 16702815
[TBL] [Abstract][Full Text] [Related]
29. Development of Promitil®, a lipidic prodrug of mitomycin c in PEGylated liposomes: From bench to bedside.
Gabizon A; Shmeeda H; Tahover E; Kornev G; Patil Y; Amitay Y; Ohana P; Sapir E; Zalipsky S
Adv Drug Deliv Rev; 2020; 154-155():13-26. PubMed ID: 32777239
[TBL] [Abstract][Full Text] [Related]
30. Phase 1 Trial of ALRN-6924, a Dual Inhibitor of MDMX and MDM2, in Patients with Solid Tumors and Lymphomas Bearing Wild-type TP53.
Saleh MN; Patel MR; Bauer TM; Goel S; Falchook GS; Shapiro GI; Chung KY; Infante JR; Conry RM; Rabinowits G; Hong DS; Wang JS; Steidl U; Naik G; Guerlavais V; Vukovic V; Annis DA; Aivado M; Meric-Bernstam F
Clin Cancer Res; 2021 Oct; 27(19):5236-5247. PubMed ID: 34301750
[TBL] [Abstract][Full Text] [Related]
31. First-in-human, open-label dose-escalation and dose-expansion study of the safety, pharmacokinetics, and antitumor effects of an oral ALK inhibitor ASP3026 in patients with advanced solid tumors.
Li T; LoRusso P; Maitland ML; Ou SH; Bahceci E; Ball HA; Park JW; Yuen G; Tolcher A
J Hematol Oncol; 2016 Mar; 9():23. PubMed ID: 26966027
[TBL] [Abstract][Full Text] [Related]
32. Phase I and pharmacokinetic study of IHL-305 (PEGylated liposomal irinotecan) in patients with advanced solid tumors.
Infante JR; Keedy VL; Jones SF; Zamboni WC; Chan E; Bendell JC; Lee W; Wu H; Ikeda S; Kodaira H; Rothenberg ML; Burris HA
Cancer Chemother Pharmacol; 2012 Nov; 70(5):699-705. PubMed ID: 22941375
[TBL] [Abstract][Full Text] [Related]
33. A Phase 1 study of BAL101553, a novel tumor checkpoint controller targeting microtubules, administered as 48-h infusion in adult patients with advanced solid tumors.
Joerger M; Stathis A; Metaxas Y; Hess D; Mantiero M; Mark M; Volden M; Kaindl T; Engelhardt M; Larger P; Lane H; Hafner P; Levy N; Stuedeli S; Sessa C; von Moos R
Invest New Drugs; 2020 Aug; 38(4):1067-1076. PubMed ID: 31471863
[TBL] [Abstract][Full Text] [Related]
34. Phase I and pharmacokinetic study of a daily times 5 short intravenous infusion schedule of 9-aminocamptothecin in a colloidal dispersion formulation in patients with advanced solid tumors.
Herben VM; van Gijn R; Schellens JH; Schot M; Lieverst J; Hillebrand MJ; Schoemaker NE; Porro MG; Beijnen JH; ten Bokkel Huinink WW
J Clin Oncol; 1999 Jun; 17(6):1906-14. PubMed ID: 10561232
[TBL] [Abstract][Full Text] [Related]
35. A phase 1 open-label, accelerated dose-escalation study of the hypoxia-activated prodrug AQ4N in patients with advanced malignancies.
Papadopoulos KP; Goel S; Beeram M; Wong A; Desai K; Haigentz M; Milián ML; Mani S; Tolcher A; Lalani AS; Sarantopoulos J
Clin Cancer Res; 2008 Nov; 14(21):7110-5. PubMed ID: 18981010
[TBL] [Abstract][Full Text] [Related]
36. Efficient Industrial Synthesis of the MDM2 Antagonist Idasanutlin via a Cu(I)-catalyzed [3+2] Asymmetric Cycloaddition.
Fishlock D; Diodone R; Hildbrand S; Kuhn B; Mössner C; Peters C; Rege PD; Rimmler G; Schantz M
Chimia (Aarau); 2018 Aug; 72(7):492-500. PubMed ID: 30158012
[TBL] [Abstract][Full Text] [Related]
37. Phase I study of paclitaxel (taxol) and pegylated liposomal doxorubicin (caelyx) administered every 2 weeks in patients with advanced solid tumors.
Mavroudis D; Kouroussis Ch; Kakolyris S; Agelaki S; Kalbakis K; Androulakis N; Souglakos J; Samonis G; Georgoulias V
Oncology; 2002; 62(3):216-22. PubMed ID: 12065868
[TBL] [Abstract][Full Text] [Related]
38. A Phase I Dose-Escalation Study Evaluating the Safety Tolerability and Pharmacokinetics of CUDC-427, a Potent, Oral, Monovalent IAP Antagonist, in Patients with Refractory Solid Tumors.
Tolcher AW; Bendell JC; Papadopoulos KP; Burris HA; Patnaik A; Fairbrother WJ; Wong H; Budha N; Darbonne WC; Peale F; Mamounas M; Royer-Joo S; Yu R; Portera CC; Infante JR
Clin Cancer Res; 2016 Sep; 22(18):4567-73. PubMed ID: 27076626
[TBL] [Abstract][Full Text] [Related]
39. Idasanutlin as a new treatment option in improving the therapeutic odyssey of relapsed/refractory AML.
Corbali MO; Eskazan AE
Future Oncol; 2020 May; 16(14):887-889. PubMed ID: 32338053
[No Abstract] [Full Text] [Related]
40. Phase I trial of UCN-01 in combination with topotecan in patients with advanced solid cancers: a Princess Margaret Hospital Phase II Consortium study.
Hotte SJ; Oza A; Winquist EW; Moore M; Chen EX; Brown S; Pond GR; Dancey JE; Hirte HW
Ann Oncol; 2006 Feb; 17(2):334-40. PubMed ID: 16284058
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
