These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 31738854)

  • 1. A Molecular Dynamics Perspective To Identify Precursors to Aggregation in Human γS-Crystallin Unravels the Mechanism of Childhood Cataracts.
    Bari KJ; Dube D; Sharma S; Chary KVR
    J Phys Chem B; 2019 Dec; 123(49):10384-10393. PubMed ID: 31738854
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enhanced H/D exchange unravels sequential structural excursions in G57W variant of human γS-crystallin with pro-cataractogenic conformations.
    Bari KJ; Sharma S; Chary KVR
    Biochem Biophys Res Commun; 2019 Jun; 514(3):901-906. PubMed ID: 31084934
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Conformational dynamics study on human γS-crystallin as an efficient route to childhood blindness.
    Bari KJ; Sharma S; Chary KVR
    Biochem Biophys Res Commun; 2019 Apr; 511(3):679-684. PubMed ID: 30827504
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural studies on the individual domains of human γS-crystallin and its G57W mutant unfolds mechanistic insights into childhood cataracts.
    Bari KJ; Sharma S; Chary KVR
    Biochem Biophys Res Commun; 2019 Sep; 517(3):499-506. PubMed ID: 31371024
    [TBL] [Abstract][Full Text] [Related]  

  • 5. On identifying low energy conformational excited states with differential ruggedness in human γS-crystallin promoting severe infantile cataracts.
    Bari KJ; Sharma S; Chary KVR
    Biochem Biophys Res Commun; 2019 Jun; 514(3):946-952. PubMed ID: 31092325
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure of G57W mutant of human γS-crystallin and its involvement in cataract formation.
    Bari KJ; Sharma S; Chary KVR
    J Struct Biol; 2019 Mar; 205(3):72-78. PubMed ID: 30769148
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sequence specific
    Bari KJ; Sharma S; Chary KVR
    Biomol NMR Assign; 2018 Apr; 12(1):51-55. PubMed ID: 28936763
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural and functional characterization of a missense mutant of human γS-crystallin associated with dominant infantile cataracts.
    Bari KJ; Sharma S; Chary KVR
    Biochem Biophys Res Commun; 2018 Dec; 506(4):862-867. PubMed ID: 30391002
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The 18th amino acid glycine plays an essential role in maintaining the structural stabilities of γS-crystallin linking with congenital cataract.
    Zhu S; Xi Y; Xu J; Hu L; Luo C; Yao K; Chen X
    Int J Biol Macromol; 2023 Nov; 251():126339. PubMed ID: 37586630
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human αB-crystallin discriminates between aggregation-prone and function-preserving variants of a client protein.
    Sprague-Piercy MA; Wong E; Roskamp KW; Fakhoury JN; Freites JA; Tobias DJ; Martin RW
    Biochim Biophys Acta Gen Subj; 2020 Mar; 1864(3):129502. PubMed ID: 31812542
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ¹H, ¹³C, and ¹⁵N assignments of wild-type human γS-crystallin and its cataract-related variant γS-G18V.
    Brubaker WD; Martin RW
    Biomol NMR Assign; 2012 Apr; 6(1):63-7. PubMed ID: 21735120
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The cataract-causing mutation G75V promotes γS-crystallin aggregation by modifying and destabilizing the native structure.
    Zhu S; Xi XB; Duan TL; Zhai Y; Li J; Yan YB; Yao K
    Int J Biol Macromol; 2018 Oct; 117():807-814. PubMed ID: 29857103
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cumulative deamidations of the major lens protein γS-crystallin increase its aggregation during unfolding and oxidation.
    Vetter CJ; Thorn DC; Wheeler SG; Mundorff CC; Halverson KA; Wales TE; Shinde UP; Engen JR; David LL; Carver JA; Lampi KJ
    Protein Sci; 2020 Sep; 29(9):1945-1963. PubMed ID: 32697405
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The cataract-related S39C variant increases γS-crystallin sensitivity to environmental stress by destroying the intermolecular disulfide cross-links.
    Yang X; Xu J; Fu C; Jia Z; Yao K; Chen X
    Biochem Biophys Res Commun; 2020 May; 526(2):459-465. PubMed ID: 32234236
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sequence specific
    Bari KJ; Sharma S; Chary KVR
    Biomol NMR Assign; 2019 Apr; 13(1):43-47. PubMed ID: 30232732
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Preferential and specific binding of human αB-crystallin to a cataract-related variant of γS-crystallin.
    Kingsley CN; Brubaker WD; Markovic S; Diehl A; Brindley AJ; Oschkinat H; Martin RW
    Structure; 2013 Dec; 21(12):2221-7. PubMed ID: 24183572
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel F30S mutation in γS-crystallin causes autosomal dominant congenital nuclear cataract by increasing susceptibility to stresses.
    Wang KJ; Liao XY; Lin K; Xi YB; Wang S; Wan XH; Yan YB
    Int J Biol Macromol; 2021 Mar; 172():475-482. PubMed ID: 33454329
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Separating instability from aggregation propensity in γS-crystallin variants.
    Brubaker WD; Freites JA; Golchert KJ; Shapiro RA; Morikis V; Tobias DJ; Martin RW
    Biophys J; 2011 Jan; 100(2):498-506. PubMed ID: 21244846
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The cataract-associated V41M mutant of human γS-crystallin shows specific structural changes that directly enhance local surface hydrophobicity.
    Bharat SV; Shekhtman A; Pande J
    Biochem Biophys Res Commun; 2014 Jan; 443(1):110-4. PubMed ID: 24287181
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Multiple Aggregation Pathways in Human γS-Crystallin and Its Aggregation-Prone G18V Variant.
    Roskamp KW; Montelongo DM; Anorma CD; Bandak DN; Chua JA; Malecha KT; Martin RW
    Invest Ophthalmol Vis Sci; 2017 Apr; 58(4):2397-2405. PubMed ID: 28444328
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.