BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 31744261)

  • 1. Targeting the Stress-Induced Protein NUPR1 to Treat Pancreatic Adenocarcinoma.
    Santofimia-Castaño P; Xia Y; Peng L; Velázquez-Campoy A; Abián O; Lan W; Lomberk G; Urrutia R; Rizzuti B; Soubeyran P; Neira JL; Iovanna J
    Cells; 2019 Nov; 8(11):. PubMed ID: 31744261
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.
    Lan W; Santofimia-Castaño P; Swayden M; Xia Y; Zhou Z; Audebert S; Camoin L; Huang C; Peng L; Jiménez-Alesanco A; Velázquez-Campoy A; Abián O; Lomberk G; Urrutia R; Rizzuti B; Geli V; Soubeyran P; Neira JL; Iovanna J
    JCI Insight; 2020 Sep; 5(18):. PubMed ID: 32780723
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design of Inhibitors of the Intrinsically Disordered Protein NUPR1: Balance between Drug Affinity and Target Function.
    Rizzuti B; Lan W; Santofimia-Castaño P; Zhou Z; Velázquez-Campoy A; Abián O; Peng L; Neira JL; Xia Y; Iovanna JL
    Biomolecules; 2021 Oct; 11(10):. PubMed ID: 34680086
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis.
    Santofimia-Castaño P; Xia Y; Lan W; Zhou Z; Huang C; Peng L; Soubeyran P; Velázquez-Campoy A; Abián O; Rizzuti B; Neira JL; Iovanna J
    J Clin Invest; 2019 Mar; 129(6):2500-2513. PubMed ID: 30920390
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of a Drug Targeting an Intrinsically Disordered Protein Involved in Pancreatic Adenocarcinoma.
    Neira JL; Bintz J; Arruebo M; Rizzuti B; Bonacci T; Vega S; Lanas A; Velázquez-Campoy A; Iovanna JL; Abián O
    Sci Rep; 2017 Jan; 7():39732. PubMed ID: 28054562
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Amphipathic helical peptides hamper protein-protein interactions of the intrinsically disordered chromatin nuclear protein 1 (NUPR1).
    Santofimia-Castaño P; Rizzuti B; Abián O; Velázquez-Campoy A; Iovanna JL; Neira JL
    Biochim Biophys Acta Gen Subj; 2018 Jun; 1862(6):1283-1295. PubMed ID: 29530795
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Phosphorylation-Induced Switch in the Nuclear Localization Sequence of the Intrinsically Disordered NUPR1 Hampers Binding to Importin.
    Neira JL; Rizzuti B; Jiménez-Alesanco A; Palomino-Schätzlein M; Abián O; Velázquez-Campoy A; Iovanna JL
    Biomolecules; 2020 Sep; 10(9):. PubMed ID: 32933064
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting NUPR1 with the small compound ZZW-115 is an efficient strategy to treat hepatocellular carcinoma.
    Lan W; Santofimia-Castaño P; Xia Y; Zhou Z; Huang C; Fraunhoffer N; Barea D; Cervello M; Giannitrapani L; Montalto G; Peng L; Iovanna J
    Cancer Lett; 2020 Aug; 486():8-17. PubMed ID: 32446862
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting NUPR1-dependent stress granules formation to induce synthetic lethality in Kras
    Santofimia-Castaño P; Fraunhoffer N; Liu X; Bessone IF; di Magliano MP; Audebert S; Camoin L; Estaras M; Brenière M; Modesti M; Lomberk G; Urrutia R; Soubeyran P; Neira JL; Iovanna J
    EMBO Mol Med; 2024 Mar; 16(3):475-505. PubMed ID: 38360999
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combination of AAV‑mediated NUPR1 knockdown and trifluoperazine induces premature senescence in human lung adenocarcinoma A549 cells in nude mice.
    Li Y; Yin Y; Ma J; Sun Y; Zhou R; Cui B; Zhang Y; Yang J; Yan X; Liu Z; Ma Z
    Oncol Rep; 2020 Feb; 43(2):681-688. PubMed ID: 31922247
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosis.
    Santofimia-Castaño P; Lan W; Bintz J; Gayet O; Carrier A; Lomberk G; Neira JL; González A; Urrutia R; Soubeyran P; Iovanna J
    Sci Rep; 2018 Nov; 8(1):16999. PubMed ID: 30451898
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis.
    Hamidi T; Algül H; Cano CE; Sandi MJ; Molejon MI; Riemann M; Calvo EL; Lomberk G; Dagorn JC; Weih F; Urrutia R; Schmid RM; Iovanna JL
    J Clin Invest; 2012 Jun; 122(6):2092-103. PubMed ID: 22565310
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The chromatin nuclear protein NUPR1L is intrinsically disordered and binds to the same proteins as its paralogue.
    Neira JL; López MB; Sevilla P; Rizzuti B; Cámara-Artigas A; Vidal M; Iovanna JL
    Biochem J; 2018 Jul; 475(14):2271-2291. PubMed ID: 29925531
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nupr1-aurora kinase A pathway provides protection against metabolic stress-mediated autophagic-associated cell death.
    Hamidi T; Cano CE; Grasso D; Garcia MN; Sandi MJ; Calvo EL; Dagorn JC; Lomberk G; Urrutia R; Goruppi S; Carracedo A; Velasco G; Iovanna JL
    Clin Cancer Res; 2012 Oct; 18(19):5234-46. PubMed ID: 22899799
    [TBL] [Abstract][Full Text] [Related]  

  • 15. NUPR1 is a critical repressor of ferroptosis.
    Liu J; Song X; Kuang F; Zhang Q; Xie Y; Kang R; Kroemer G; Tang D
    Nat Commun; 2021 Jan; 12(1):647. PubMed ID: 33510144
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NUPR1, a new target in liver cancer: implication in controlling cell growth, migration, invasion and sorafenib resistance.
    Emma MR; Iovanna JL; Bachvarov D; Puleio R; Loria GR; Augello G; Candido S; Libra M; Gulino A; Cancila V; McCubrey JA; Montalto G; Cervello M
    Cell Death Dis; 2016 Jun; 7(6):e2269. PubMed ID: 27336713
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functional Characterization of Nupr1L, A Novel p53-Regulated Isoform of the High-Mobility Group (HMG)-Related Protumoral Protein Nupr1.
    Lopez MB; Garcia MN; Grasso D; Bintz J; Molejon MI; Velez G; Lomberk G; Neira JL; Urrutia R; Iovanna J
    J Cell Physiol; 2015 Dec; 230(12):2936-50. PubMed ID: 25899918
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lentivirus-mediated RNAi knockdown of NUPR1 inhibits human nonsmall cell lung cancer growth in vitro and in vivo.
    Guo X; Wang W; Hu J; Feng K; Pan Y; Zhang L; Feng Y
    Anat Rec (Hoboken); 2012 Dec; 295(12):2114-21. PubMed ID: 22961798
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dendrimers as Competitors of Protein-Protein Interactions of the Intrinsically Disordered Nuclear Chromatin Protein NUPR1.
    Neira JL; Correa J; Rizzuti B; Santofimia-Castaño P; Abian O; Velázquez-Campoy A; Fernandez-Megia E; Iovanna JL
    Biomacromolecules; 2019 Jul; 20(7):2567-2576. PubMed ID: 31181156
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hepatitis B virus X promotes hepatocellular carcinoma development via nuclear protein 1 pathway.
    Bak Y; Shin HJ; Bak Is; Yoon DY; Yu DY
    Biochem Biophys Res Commun; 2015 Oct; 466(4):676-81. PubMed ID: 26392315
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.