These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 31745860)

  • 21. CSF levels of the BACE1 substrate NRG1 correlate with cognition in Alzheimer's disease.
    Mouton-Liger F; Dumurgier J; Cognat E; Hourregue C; Zetterberg H; Vanderstichele H; Vanmechelen E; Bouaziz-Amar E; Blennow K; Hugon J; Paquet C
    Alzheimers Res Ther; 2020 Jul; 12(1):88. PubMed ID: 32690068
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
    Ye X; Feng T; Tammineni P; Chang Q; Jeong YY; Margolis DJ; Cai H; Kusnecov A; Cai Q
    J Neurosci; 2017 Mar; 37(10):2639-2655. PubMed ID: 28159908
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Genetic association of BACE1 gene polymorphism C786G with late-onset Alzheimer's disease in Chinese.
    Kan R; Wang B; Zhang C; Jin F; Yang Z; Ji S; Lu Z; Zheng C; Wang L
    J Mol Neurosci; 2005; 25(2):127-31. PubMed ID: 15784960
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Increased CSF-BACE1 activity associated with decreased hippocampus volume in Alzheimer's disease.
    Ewers M; Cheng X; Zhong Z; Nural HF; Walsh C; Meindl T; Teipel SJ; Buerger K; He P; Shen Y; Hampel H
    J Alzheimers Dis; 2011; 25(2):373-81. PubMed ID: 21460439
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Levels of beta-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment.
    Zhong Z; Ewers M; Teipel S; Bürger K; Wallin A; Blennow K; He P; McAllister C; Hampel H; Shen Y
    Arch Gen Psychiatry; 2007 Jun; 64(6):718-26. PubMed ID: 17548753
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Decrease in brain soluble amyloid precursor protein β (sAPPβ) in Alzheimer's disease cortex.
    Wu G; Sankaranarayanan S; Hsieh SH; Simon AJ; Savage MJ
    J Neurosci Res; 2011 Jun; 89(6):822-32. PubMed ID: 21433051
    [TBL] [Abstract][Full Text] [Related]  

  • 27. BACE1 Cleavage Site Selection Critical for Amyloidogenesis and Alzheimer's Pathogenesis.
    Zhang S; Wang Z; Cai F; Zhang M; Wu Y; Zhang J; Song W
    J Neurosci; 2017 Jul; 37(29):6915-6925. PubMed ID: 28626014
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Energy inhibition elevates beta-secretase levels and activity and is potentially amyloidogenic in APP transgenic mice: possible early events in Alzheimer's disease pathogenesis.
    Velliquette RA; O'Connor T; Vassar R
    J Neurosci; 2005 Nov; 25(47):10874-83. PubMed ID: 16306400
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Camelid heavy chain only antibody fragment domain against β-site of amyloid precursor protein cleaving enzyme 1 inhibits β-secretase activity in vitro and in vivo.
    Dorresteijn B; Rotman M; Faber D; Schravesande R; Suidgeest E; van der Weerd L; van der Maarel SM; Verrips CT; El Khattabi M
    FEBS J; 2015 Sep; 282(18):3618-31. PubMed ID: 26147692
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The Cerebrospinal Fluid Neurogranin/BACE1 Ratio is a Potential Correlate of Cognitive Decline in Alzheimer's Disease.
    De Vos A; Struyfs H; Jacobs D; Fransen E; Klewansky T; De Roeck E; Robberecht C; Van Broeckhoven C; Duyckaerts C; Engelborghs S; Vanmechelen E
    J Alzheimers Dis; 2016 Jul; 53(4):1523-38. PubMed ID: 27392859
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
    Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
    Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
    [TBL] [Abstract][Full Text] [Related]  

  • 32. BACE1 Function and Inhibition: Implications of Intervention in the Amyloid Pathway of Alzheimer's Disease Pathology.
    Koelsch G
    Molecules; 2017 Oct; 22(10):. PubMed ID: 29027981
    [TBL] [Abstract][Full Text] [Related]  

  • 33. BACE1: from biomarker to Alzheimer's disease therapeutical target.
    Cervellati C; Valacchi G; Zuliani G
    Aging (Albany NY); 2021 May; 13(9):12299-12300. PubMed ID: 33982671
    [No Abstract]   [Full Text] [Related]  

  • 34. Beta-secretase inhibitors in phase I and phase II clinical trials for Alzheimer's disease.
    Moussa CE
    Expert Opin Investig Drugs; 2017 Oct; 26(10):1131-1136. PubMed ID: 28817311
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The transmembrane domain of the Alzheimer's beta-secretase (BACE1) determines its late Golgi localization and access to beta -amyloid precursor protein (APP) substrate.
    Yan R; Han P; Miao H; Greengard P; Xu H
    J Biol Chem; 2001 Sep; 276(39):36788-96. PubMed ID: 11466313
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Reduction of the expression of the late-onset Alzheimer's disease (AD) risk-factor
    Andrew RJ; De Rossi P; Nguyen P; Kowalski HR; Recupero AJ; Guerbette T; Krause SV; Rice RC; Laury-Kleintop L; Wagner SL; Thinakaran G
    J Biol Chem; 2019 Mar; 294(12):4477-4487. PubMed ID: 30692199
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Cerebrospinal fluid BACE1 activity and brain amyloid load in Alzheimer's disease.
    Grimmer T; Alexopoulos P; Tsolakidou A; Guo LH; Henriksen G; Yousefi BH; Förstl H; Sorg C; Kurz A; Drzezga A; Perneczky R
    ScientificWorldJournal; 2012; 2012():712048. PubMed ID: 22272179
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) as a biological candidate marker of Alzheimer's disease.
    Hampel H; Shen Y
    Scand J Clin Lab Invest; 2009; 69(1):8-12. PubMed ID: 18609117
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Identification of a BACE1 Binding Peptide Candidate for the Prevention of Amyloid Beta in Alzheimer's Disease.
    Read J; Suphioglu C
    Cell Physiol Biochem; 2019; 53(2):413-428. PubMed ID: 31415717
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The cysteine protease inhibitor, E64d, reduces brain amyloid-β and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, β-secretase activity.
    Hook G; Hook V; Kindy M
    J Alzheimers Dis; 2011; 26(2):387-408. PubMed ID: 21613740
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.