These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 31748641)

  • 1. Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis.
    Flora GD; Sahli KA; Sasikumar P; Holbrook LM; Stainer AR; AlOuda SK; Crescente M; Sage T; Unsworth AJ; Gibbins JM
    Sci Rep; 2019 Nov; 9(1):17210. PubMed ID: 31748641
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pregnane X Receptor Activation Triggers Rapid ATP Release in Primed Macrophages That Mediates NLRP3 Inflammasome Activation.
    Hudson G; Flannigan KL; Venu VKP; Alston L; Sandall CF; MacDonald JA; Muruve DA; Chang TKH; Mani S; Hirota SA
    J Pharmacol Exp Ther; 2019 Jul; 370(1):44-53. PubMed ID: 31004077
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Coactivator binding promotes the specific interaction between ligand and the pregnane X receptor.
    Watkins RE; Davis-Searles PR; Lambert MH; Redinbo MR
    J Mol Biol; 2003 Aug; 331(4):815-28. PubMed ID: 12909012
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Platelet Activation and Thrombus Formation over IgG Immune Complexes Requires Integrin αIIbβ3 and Lyn Kinase.
    Zhi H; Dai J; Liu J; Zhu J; Newman DK; Gao C; Newman PJ
    PLoS One; 2015; 10(8):e0135738. PubMed ID: 26291522
    [TBL] [Abstract][Full Text] [Related]  

  • 5. NLRP3 regulates platelet integrin αIIbβ3 outside-in signaling, hemostasis and arterial thrombosis.
    Qiao J; Wu X; Luo Q; Wei G; Xu M; Wu Y; Liu Y; Li X; Zi J; Ju W; Fu L; Chen C; Wu Q; Zhu S; Qi K; Li D; Li Z; Andrews RK; Zeng L; Gardiner EE; Xu K
    Haematologica; 2018 Sep; 103(9):1568-1576. PubMed ID: 29794149
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mice lacking the SLAM family member CD84 display unaltered platelet function in hemostasis and thrombosis.
    Hofmann S; Braun A; Pozgaj R; Morowski M; Vögtle T; Nieswandt B
    PLoS One; 2014; 9(12):e115306. PubMed ID: 25551754
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Receptor-interacting protein kinase 3 promotes platelet activation and thrombosis.
    Zhang Y; Zhang J; Yan R; Tian J; Zhang Y; Zhang J; Chen M; Cui Q; Zhao L; Hu R; Jiang M; Li Z; Ruan C; He S; Dai K
    Proc Natl Acad Sci U S A; 2017 Mar; 114(11):2964-2969. PubMed ID: 28242694
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Xenobiotic Nuclear Receptors Pregnane X Receptor and Constitutive Androstane Receptor Regulate Antiretroviral Drug Efflux Transporters at the Blood-Testis Barrier.
    Whyte-Allman SK; Hoque MT; Jenabian MA; Routy JP; Bendayan R
    J Pharmacol Exp Ther; 2017 Dec; 363(3):324-335. PubMed ID: 28970358
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The role of platelet and endothelial GARP in thrombosis and hemostasis.
    Vermeersch E; Denorme F; Maes W; De Meyer SF; Vanhoorelbeke K; Edwards J; Shevach EM; Unutmaz D; Fujii H; Deckmyn H; Tersteeg C
    PLoS One; 2017; 12(3):e0173329. PubMed ID: 28278197
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A pharmacophore for human pregnane X receptor ligands.
    Ekins S; Erickson JA
    Drug Metab Dispos; 2002 Jan; 30(1):96-9. PubMed ID: 11744617
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The G-protein βγ subunits regulate platelet function.
    Alarabi AB; Karim ZA; Hinojos V; Lozano PA; Hernandez KR; Montes Ramirez JE; Ali HEA; Khasawneh FT; Alshbool FZ
    Life Sci; 2020 Dec; 262():118481. PubMed ID: 32971104
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The pregnane X receptor down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for ("squelching") SRC-1 coactivator.
    Hyrsova L; Smutny T; Carazo A; Moravcik S; Mandikova J; Trejtnar F; Gerbal-Chaloin S; Pavek P
    Br J Pharmacol; 2016 May; 173(10):1703-15. PubMed ID: 26920453
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The role of residues T248, Y249 and T422 in the function of human pregnane X receptor.
    Doricakova A; Novotna A; Vrzal R; Pavek P; Dvorak Z
    Arch Toxicol; 2013 Feb; 87(2):291-301. PubMed ID: 22976785
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functional Interaction between Pregnane X Receptor and Yes-Associated Protein in Xenobiotic-Dependent Liver Hypertrophy and Drug Metabolism.
    Abe T; Shizu R; Sasaki T; Shimizu Y; Hosaka T; Kodama S; Matsuzawa A; Yoshinari K
    J Pharmacol Exp Ther; 2019 Dec; 371(3):590-601. PubMed ID: 31533970
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Strategies for developing pregnane X receptor antagonists: Implications from metabolism to cancer.
    Chai SC; Wright WC; Chen T
    Med Res Rev; 2020 May; 40(3):1061-1083. PubMed ID: 31782213
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gintonin modulates platelet function and inhibits thrombus formation via impaired glycoprotein VI signaling.
    Irfan M; Jeong D; Saba E; Kwon HW; Shin JH; Jeon BR; Kim S; Kim SD; Lee DH; Nah SY; Rhee MH
    Platelets; 2019; 30(5):589-598. PubMed ID: 29870296
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dietary phytochemicals as modulators of human pregnane X receptor.
    Zhang J; Pavek P; Kamaraj R; Ren L; Zhang T
    Crit Rev Food Sci Nutr; 2023; 63(19):3279-3301. PubMed ID: 34698593
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Vascular Smooth Muscle Cells Stimulate Platelets and Facilitate Thrombus Formation through Platelet CLEC-2: Implications in Atherothrombosis.
    Inoue O; Hokamura K; Shirai T; Osada M; Tsukiji N; Hatakeyama K; Umemura K; Asada Y; Suzuki-Inoue K; Ozaki Y
    PLoS One; 2015; 10(9):e0139357. PubMed ID: 26418160
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New opportunities for pregnane X receptor (PXR) targeting in drug development. lessons from Enantio- and species-specific PXR ligands identified from a discovery library of amino acid analogues.
    Wipf P; Gong H; Janjic JM; Li S; Day BW; Xie W
    Mini Rev Med Chem; 2007 Jun; 7(6):617-25. PubMed ID: 17584160
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Platycodin D inhibits platelet function and thrombus formation through inducing internalization of platelet glycoprotein receptors.
    Luo Q; Wei G; Wu X; Tang K; Xu M; Wu Y; Liu Y; Li X; Sun Z; Ju W; Qi K; Chen C; Yan Z; Cheng H; Zhu F; Li Z; Zeng L; Xu K; Qiao J
    J Transl Med; 2018 Nov; 16(1):311. PubMed ID: 30442147
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.