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5. Co-targeting HGF/cMET Signaling with MEK Inhibitors in Metastatic Uveal Melanoma. Cheng H; Chua V; Liao C; Purwin TJ; Terai M; Kageyama K; Davies MA; Sato T; Aplin AE Mol Cancer Ther; 2017 Mar; 16(3):516-528. PubMed ID: 28138035 [TBL] [Abstract][Full Text] [Related]
6. Combination small molecule MEK and PI3K inhibition enhances uveal melanoma cell death in a mutant GNAQ- and GNA11-dependent manner. Khalili JS; Yu X; Wang J; Hayes BC; Davies MA; Lizee G; Esmaeli B; Woodman SE Clin Cancer Res; 2012 Aug; 18(16):4345-55. PubMed ID: 22733540 [TBL] [Abstract][Full Text] [Related]
7. Paracrine Effect of NRG1 and HGF Drives Resistance to MEK Inhibitors in Metastatic Uveal Melanoma. Cheng H; Terai M; Kageyama K; Ozaki S; McCue PA; Sato T; Aplin AE Cancer Res; 2015 Jul; 75(13):2737-48. PubMed ID: 25952648 [TBL] [Abstract][Full Text] [Related]
8. Active notch protects MAPK activated melanoma cell lines from MEK inhibitor cobimetinib. Porcelli L; Mazzotta A; Garofoli M; Di Fonte R; Guida G; Guida M; Tommasi S; Azzariti A Biomed Pharmacother; 2021 Jan; 133():111006. PubMed ID: 33202284 [TBL] [Abstract][Full Text] [Related]
9. Preclinical evaluation of drug combinations identifies co-inhibition of Bcl-2/XL/W and MDM2 as a potential therapy in uveal melanoma. Decaudin D; Frisch Dit Leitz E; Nemati F; Tarin M; Naguez A; Zerara M; Marande B; Vivet-Noguer R; Halilovic E; Fabre C; Jochemsen A; Roman-Roman S; Alsafadi S Eur J Cancer; 2020 Feb; 126():93-103. PubMed ID: 31927215 [TBL] [Abstract][Full Text] [Related]
10. HDAC11 activity contributes to MEK inhibitor escape in uveal melanoma. Sriramareddy SN; Faião-Flores F; Emmons MF; Saha B; Chellappan S; Wyatt C; Smalley I; Licht JD; Durante MA; Harbour JW; Smalley KSM Cancer Gene Ther; 2022 Dec; 29(12):1840-1846. PubMed ID: 35332245 [TBL] [Abstract][Full Text] [Related]
12. The protein kinase C inhibitor enzastaurin exhibits antitumor activity against uveal melanoma. Wu X; Zhu M; Fletcher JA; Giobbie-Hurder A; Hodi FS PLoS One; 2012; 7(1):e29622. PubMed ID: 22253748 [TBL] [Abstract][Full Text] [Related]
13. Dasatinib sensitises KRAS-mutant cancer cells to mitogen-activated protein kinase kinase inhibitor via inhibition of TAZ activity. Rao G; Kim IK; Conforti F; Liu J; Zhang YW; Giaccone G Eur J Cancer; 2018 Aug; 99():37-48. PubMed ID: 29902613 [TBL] [Abstract][Full Text] [Related]
14. Inhibition of MEK suppresses hepatocellular carcinoma growth through independent MYC and BIM regulation. Zhou X; Zhu A; Gu X; Xie G Cell Oncol (Dordr); 2019 Jun; 42(3):369-380. PubMed ID: 30788663 [TBL] [Abstract][Full Text] [Related]
15. The synergistic antitumor effect of combination therapy with a MEK inhibitor and YAP inhibitor on pERK-positive neuroblastoma. Takemoto M; Tanaka T; Tsuji R; Togashi Y; Higashi M; Fumino S; Tajiri T Biochem Biophys Res Commun; 2021 Sep; 570():41-46. PubMed ID: 34271435 [TBL] [Abstract][Full Text] [Related]
16. In vitro and in vivo anti-uveal melanoma activity of JSL-1, a novel HDAC inhibitor. Wang Y; Liu M; Jin Y; Jiang S; Pan J Cancer Lett; 2017 Aug; 400():47-60. PubMed ID: 28455241 [TBL] [Abstract][Full Text] [Related]
17. Monosomy 3 Is Linked to Resistance to MEK Inhibitors in Uveal Melanoma. Mergener S; Siveke JT; Peña-Llopis S Int J Mol Sci; 2021 Jun; 22(13):. PubMed ID: 34201614 [TBL] [Abstract][Full Text] [Related]
18. BRAF and MEK Inhibitors Increase PD-1-Positive Melanoma Cells Leading to a Potential Lymphocyte-Independent Synergism with Anti-PD-1 Antibody. Sanlorenzo M; Vujic I; Floris A; Novelli M; Gammaitoni L; Giraudo L; Macagno M; Leuci V; Rotolo R; Donini C; Basiricò M; Quaglino P; Fierro MT; Giordano S; Sibilia M; Carnevale-Schianca F; Aglietta M; Sangiolo D Clin Cancer Res; 2018 Jul; 24(14):3377-3385. PubMed ID: 29650750 [No Abstract] [Full Text] [Related]
19. Combined Inhibition of SHP2 and MEK Is Effective in Models of NF1-Deficient Malignant Peripheral Nerve Sheath Tumors. Wang J; Pollard K; Allen AN; Tomar T; Pijnenburg D; Yao Z; Rodriguez FJ; Pratilas CA Cancer Res; 2020 Dec; 80(23):5367-5379. PubMed ID: 33032988 [TBL] [Abstract][Full Text] [Related]
20. The HSP90 inhibitor, NVP-AUY922, sensitizes KRAS-mutant non-small cell lung cancer with intrinsic resistance to MEK inhibitor, trametinib. Park KS; Oh B; Lee MH; Nam KY; Jin HR; Yang H; Choi J; Kim SW; Lee DH Cancer Lett; 2016 Mar; 372(1):75-81. PubMed ID: 26723875 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]