BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

475 related articles for article (PubMed ID: 31761566)

  • 1. Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis.
    Sun X; Seidman JS; Zhao P; Troutman TD; Spann NJ; Que X; Zhou F; Liao Z; Pasillas M; Yang X; Magida JA; Kisseleva T; Brenner DA; Downes M; Evans RM; Saltiel AR; Tsimikas S; Glass CK; Witztum JL
    Cell Metab; 2020 Jan; 31(1):189-206.e8. PubMed ID: 31761566
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice.
    Que X; Hung MY; Yeang C; Gonen A; Prohaska TA; Sun X; Diehl C; Määttä A; Gaddis DE; Bowden K; Pattison J; MacDonald JG; Ylä-Herttuala S; Mellon PL; Hedrick CC; Ley K; Miller YI; Glass CK; Peterson KL; Binder CJ; Tsimikas S; Witztum JL
    Nature; 2018 Jun; 558(7709):301-306. PubMed ID: 29875409
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nobiletin mitigates hepatocytes death, liver inflammation, and fibrosis in a murine model of NASH through modulating hepatic oxidative stress and mitochondrial dysfunction.
    Li S; Li X; Chen F; Liu M; Ning L; Yan Y; Zhang S; Huang S; Tu C
    J Nutr Biochem; 2022 Feb; 100():108888. PubMed ID: 34695558
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fucoxanthin inhibits hepatic oxidative stress, inflammation, and fibrosis in diet-induced nonalcoholic steatohepatitis model mice.
    Takatani N; Kono Y; Beppu F; Okamatsu-Ogura Y; Yamano Y; Miyashita K; Hosokawa M
    Biochem Biophys Res Commun; 2020 Jul; 528(2):305-310. PubMed ID: 32475638
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nonalcoholic steatohepatitis severity is defined by a failure in compensatory antioxidant capacity in the setting of mitochondrial dysfunction.
    Boland ML; Oldham S; Boland BB; Will S; Lapointe JM; Guionaud S; Rhodes CJ; Trevaskis JL
    World J Gastroenterol; 2018 Apr; 24(16):1748-1765. PubMed ID: 29713129
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice.
    Bettaieb A; Jiang JX; Sasaki Y; Chao TI; Kiss Z; Chen X; Tian J; Katsuyama M; Yabe-Nishimura C; Xi Y; Szyndralewiez C; Schröder K; Shah A; Brandes RP; Haj FG; Török NJ
    Gastroenterology; 2015 Aug; 149(2):468-80.e10. PubMed ID: 25888330
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ezetimibe suppresses development of liver tumors by inhibiting angiogenesis in mice fed a high-fat diet.
    Miura K; Ohnishi H; Morimoto N; Minami S; Ishioka M; Watanabe S; Tsukui M; Takaoka Y; Nomoto H; Isoda N; Yamamoto H
    Cancer Sci; 2019 Feb; 110(2):771-783. PubMed ID: 30520543
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gemcabene downregulates inflammatory, lipid-altering and cell-signaling genes in the STAM™ model of NASH.
    Oniciu DC; Hashiguchi T; Shibazaki Y; Bisgaier CL
    PLoS One; 2018; 13(5):e0194568. PubMed ID: 29847555
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The indole derivative NecroX-7 improves nonalcoholic steatohepatitis in ob/ob mice through suppression of mitochondrial ROS/RNS and inflammation.
    Chung HK; Kim YK; Park JH; Ryu MJ; Chang JY; Hwang JH; Lee CH; Kim SH; Kim HJ; Kweon GR; Kim KS; Shong M
    Liver Int; 2015 Apr; 35(4):1341-53. PubMed ID: 25443620
    [TBL] [Abstract][Full Text] [Related]  

  • 10. STARD1 promotes NASH-driven HCC by sustaining the generation of bile acids through the alternative mitochondrial pathway.
    Conde de la Rosa L; Garcia-Ruiz C; Vallejo C; Baulies A; Nuñez S; Monte MJ; Marin JJG; Baila-Rueda L; Cenarro A; Civeira F; Fuster J; Garcia-Valdecasas JC; Ferrer J; Karin M; Ribas V; Fernandez-Checa JC
    J Hepatol; 2021 Jun; 74(6):1429-1441. PubMed ID: 33515644
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mitochondria- and NOX4-dependent antioxidant defense mitigates progression to nonalcoholic steatohepatitis in obesity.
    Greatorex S; Kaur S; Xirouchaki CE; Goh PK; Wiede F; Genders AJ; Tran M; Jia Y; Raajendiran A; Brown WA; McLean CA; Sadoshima J; Watt MJ; Tiganis T
    J Clin Invest; 2023 Dec; 134(3):. PubMed ID: 38060313
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Neutralization of oxidized phospholipids attenuates age-associated bone loss in mice.
    Palmieri M; Almeida M; Nookaew I; Gomez-Acevedo H; Joseph TE; Que X; Tsimikas S; Sun X; Manolagas SC; Witztum JL; Ambrogini E
    Aging Cell; 2021 Aug; 20(8):e13442. PubMed ID: 34278710
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Toyocamycin attenuates free fatty acid-induced hepatic steatosis and apoptosis in cultured hepatocytes and ameliorates nonalcoholic fatty liver disease in mice.
    Takahara I; Akazawa Y; Tabuchi M; Matsuda K; Miyaaki H; Kido Y; Kanda Y; Taura N; Ohnita K; Takeshima F; Sakai Y; Eguchi S; Nakashima M; Nakao K
    PLoS One; 2017; 12(3):e0170591. PubMed ID: 28278289
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Polydatin attenuates diet-induced nonalcoholic steatohepatitis and fibrosis in mice.
    Li R; Li J; Huang Y; Li H; Yan S; Lin J; Chen Y; Wu L; Liu B; Wang G; Lan T
    Int J Biol Sci; 2018; 14(11):1411-1425. PubMed ID: 30262993
    [No Abstract]   [Full Text] [Related]  

  • 15. Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC.
    Grohmann M; Wiede F; Dodd GT; Gurzov EN; Ooi GJ; Butt T; Rasmiena AA; Kaur S; Gulati T; Goh PK; Treloar AE; Archer S; Brown WA; Muller M; Watt MJ; Ohara O; McLean CA; Tiganis T
    Cell; 2018 Nov; 175(5):1289-1306.e20. PubMed ID: 30454647
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitochondrial Adaptation in Nonalcoholic Fatty Liver Disease: Novel Mechanisms and Treatment Strategies.
    Sunny NE; Bril F; Cusi K
    Trends Endocrinol Metab; 2017 Apr; 28(4):250-260. PubMed ID: 27986466
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting oxidized phospholipids by AAV-based gene therapy in mice with established hepatic steatosis prevents progression to fibrosis.
    Upchurch CM; Yeudall S; Pavelec CM; Merk D; Greulich J; Manjegowda M; Raghavan SS; Bochkis IM; Scott MM; Perez-Reyes E; Leitinger N
    Sci Adv; 2022 Jul; 8(28):eabn0050. PubMed ID: 35857497
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A TNFα/Miz1-positive feedback loop inhibits mitophagy in hepatocytes and propagates non-alcoholic steatohepatitis.
    Jin K; Shi Y; Zhang H; Zhangyuan G; Wang F; Li S; Chen C; Zhang J; Wang H; Zhang W; Sun B
    J Hepatol; 2023 Aug; 79(2):403-416. PubMed ID: 37040844
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Disruption of hepatic small heterodimer partner induces dissociation of steatosis and inflammation in experimental nonalcoholic steatohepatitis.
    Magee N; Zou A; Ghosh P; Ahamed F; Delker D; Zhang Y
    J Biol Chem; 2020 Jan; 295(4):994-1008. PubMed ID: 31831621
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Oxidative Stress in NAFLD: Role of Nutrients and Food Contaminants.
    Rives C; Fougerat A; Ellero-Simatos S; Loiseau N; Guillou H; Gamet-Payrastre L; Wahli W
    Biomolecules; 2020 Dec; 10(12):. PubMed ID: 33371482
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.