BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 31772034)

  • 1. Characterization and Optimization of the Novel Transient Receptor Potential Melastatin 2 Antagonist tatM2NX.
    Cruz-Torres I; Backos DS; Herson PS
    Mol Pharmacol; 2020 Feb; 97(2):102-111. PubMed ID: 31772034
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349.
    Fliegert R; Watt JM; Schöbel A; Rozewitz MD; Moreau C; Kirchberger T; Thomas MP; Sick W; Araujo AC; Harneit A; Potter BVL; Guse AH
    Biochem J; 2017 Jun; 474(13):2159-2175. PubMed ID: 28515263
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selective inhibition of TRPM2 channel by two novel synthesized ADPR analogues.
    Luo X; Li M; Zhan K; Yang W; Zhang L; Wang K; Yu P; Zhang L
    Chem Biol Drug Des; 2018 Feb; 91(2):552-566. PubMed ID: 29034580
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibitory effects of AG490 on H2O2-induced TRPM2-mediated Ca(2+) entry.
    Shimizu S; Yonezawa R; Hagiwara T; Yoshida T; Takahashi N; Hamano S; Negoro T; Toda T; Wakamori M; Mori Y; Ishii M
    Eur J Pharmacol; 2014 Nov; 742():22-30. PubMed ID: 25179574
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TRPM2 cation channels, oxidative stress and neurological diseases: where are we now?
    Nazıroğlu M
    Neurochem Res; 2011 Mar; 36(3):355-66. PubMed ID: 21140288
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Protective Effects of Duloxetine against Cerebral Ischemia-Reperfusion Injury via Transient Receptor Potential Melastatin 2 Inhibition.
    Toda T; Yamamoto S; Umehara N; Mori Y; Wakamori M; Shimizu S
    J Pharmacol Exp Ther; 2019 Feb; 368(2):246-254. PubMed ID: 30523061
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-activity relationship of adenosine 5'-diphosphoribose at the transient receptor potential melastatin 2 (TRPM2) channel: rational design of antagonists.
    Moreau C; Kirchberger T; Swarbrick JM; Bartlett SJ; Fliegert R; Yorgan T; Bauche A; Harneit A; Guse AH; Potter BV
    J Med Chem; 2013 Dec; 56(24):10079-102. PubMed ID: 24304219
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Divalent copper is a potent extracellular blocker for TRPM2 channel.
    Zeng B; Chen GL; Xu SZ
    Biochem Biophys Res Commun; 2012 Jul; 424(2):279-84. PubMed ID: 22750002
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism of TRPM2 channel gating revealed by cryo-EM.
    Xia S; Wang L; Fu TM; Wu H
    FEBS J; 2019 Sep; 286(17):3333-3339. PubMed ID: 31144442
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of TRPM2 channel in mediating H2O2-induced Ca2+ entry and endothelial hyperpermeability.
    Hecquet CM; Ahmmed GU; Vogel SM; Malik AB
    Circ Res; 2008 Feb; 102(3):347-55. PubMed ID: 18048770
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and biological activities of 2,3-dihydroquinazolin-4(1H)-one derivatives as TRPM2 inhibitors.
    Zhang H; Liu H; Luo X; Wang Y; Liu Y; Jin H; Liu Z; Yang W; Yu P; Zhang L; Zhang L
    Eur J Med Chem; 2018 May; 152():235-252. PubMed ID: 29723786
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and biological activities of benzo[d]imidazo[1,2-a]imidazole derivatives as TRPM2-specfic inhibitors.
    Zhao S; Zhang H; Jin H; Cai X; Zhang R; Jin Z; Yang W; Yu P; Zhang L; Liu Z
    Eur J Med Chem; 2021 Dec; 225():113750. PubMed ID: 34416664
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of TRPM2 by extra- and intracellular calcium.
    Starkus J; Beck A; Fleig A; Penner R
    J Gen Physiol; 2007 Oct; 130(4):427-40. PubMed ID: 17893195
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase.
    Fonfria E; Marshall IC; Benham CD; Boyfield I; Brown JD; Hill K; Hughes JP; Skaper SD; McNulty S
    Br J Pharmacol; 2004 Sep; 143(1):186-92. PubMed ID: 15302683
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation of TRPM2 and TRPV1 Channels in Dorsal Root Ganglion by NADPH Oxidase and Protein Kinase C Molecular Pathways: a Patch Clamp Study.
    Nazıroğlu M
    J Mol Neurosci; 2017 Mar; 61(3):425-435. PubMed ID: 28097492
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of the transient receptor potential cation channel TRPM2 by 2-aminoethoxydiphenyl borate (2-APB).
    Togashi K; Inada H; Tominaga M
    Br J Pharmacol; 2008 Mar; 153(6):1324-30. PubMed ID: 18204483
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transient receptor potential melastatin 2 is required for lipopolysaccharide-induced cytokine production in human monocytes.
    Wehrhahn J; Kraft R; Harteneck C; Hauschildt S
    J Immunol; 2010 Mar; 184(5):2386-93. PubMed ID: 20107186
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Endogenous ADP-ribose enables calcium-regulated cation currents through TRPM2 channels in neutrophil granulocytes.
    Heiner I; Eisfeld J; Warnstedt M; Radukina N; Jüngling E; Lückhoff A
    Biochem J; 2006 Sep; 398(2):225-32. PubMed ID: 16719842
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sensitization of H2O2-induced TRPM2 activation and subsequent interleukin-8 (CXCL8) production by intracellular Fe(2+) in human monocytic U937 cells.
    Shimizu S; Yonezawa R; Negoro T; Yamamoto S; Numata T; Ishii M; Mori Y; Toda T
    Int J Biochem Cell Biol; 2015 Nov; 68():119-27. PubMed ID: 26386353
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Critical intracellular Ca2+ dependence of transient receptor potential melastatin 2 (TRPM2) cation channel activation.
    McHugh D; Flemming R; Xu SZ; Perraud AL; Beech DJ
    J Biol Chem; 2003 Mar; 278(13):11002-6. PubMed ID: 12529379
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.