BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 31772299)

  • 1. Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL.
    Rodriguez S; Abundis C; Boccalatte F; Mehrotra P; Chiang MY; Yui MA; Wang L; Zhang H; Zollman A; Bonfim-Silva R; Kloetgen A; Palmer J; Sandusky G; Wunderlich M; Kaplan MH; Mulloy JC; Marcucci G; Aifantis I; Cardoso AA; Carlesso N
    Leukemia; 2020 May; 34(5):1241-1252. PubMed ID: 31772299
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The p27-Skp2 axis mediates glucocorticoid-induced cell cycle arrest in T-lymphoma cells.
    Kullmann MK; Grubbauer C; Goetsch K; Jäkel H; Podmirseg SR; Trockenbacher A; Ploner C; Cato AC; Weiss C; Kofler R; Hengst L
    Cell Cycle; 2013 Aug; 12(16):2625-35. PubMed ID: 23907123
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DLL4 regulates NOTCH signaling and growth of T acute lymphoblastic leukemia cells in NOD/SCID mice.
    Minuzzo S; Agnusdei V; Pusceddu I; Pinazza M; Moserle L; Masiero M; Rossi E; Crescenzi M; Hoey T; Ponzoni M; Amadori A; Indraccolo S
    Carcinogenesis; 2015 Jan; 36(1):115-21. PubMed ID: 25355291
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nuclear pro-IL-16 regulation of T cell proliferation: p27(KIP1)-dependent G0/G1 arrest mediated by inhibition of Skp2 transcription.
    Center DM; Cruikshank WW; Zhang Y
    J Immunol; 2004 Feb; 172(3):1654-60. PubMed ID: 14734747
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeted Inhibition of the E3 Ligase SCF
    Zhao H; Iqbal NJ; Sukrithan V; Nicholas C; Xue Y; Yu C; Locker J; Zou J; Schwartz EL; Zhu L
    Cancer Res; 2020 Jun; 80(11):2355-2367. PubMed ID: 32265224
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication.
    Nakayama K; Nagahama H; Minamishima YA; Matsumoto M; Nakamichi I; Kitagawa K; Shirane M; Tsunematsu R; Tsukiyama T; Ishida N; Kitagawa M; Nakayama K; Hatakeyama S
    EMBO J; 2000 May; 19(9):2069-81. PubMed ID: 10790373
    [TBL] [Abstract][Full Text] [Related]  

  • 7. STAT1 represses Skp2 gene transcription to promote p27Kip1 stabilization in Ras-transformed cells.
    Wang S; Raven JF; Koromilas AE
    Mol Cancer Res; 2010 May; 8(5):798-805. PubMed ID: 20407011
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27 Kip1 degradation.
    Sarmento LM; Huang H; Limon A; Gordon W; Fernandes J; Tavares MJ; Miele L; Cardoso AA; Classon M; Carlesso N
    J Exp Med; 2005 Jul; 202(1):157-68. PubMed ID: 15998794
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cell adhesion induces p27Kip1-associated cell-cycle arrest through down-regulation of the SCFSkp2 ubiquitin ligase pathway in mantle-cell and other non-Hodgkin B-cell lymphomas.
    Lwin T; Hazlehurst LA; Dessureault S; Lai R; Bai W; Sotomayor E; Moscinski LC; Dalton WS; Tao J
    Blood; 2007 Sep; 110(5):1631-8. PubMed ID: 17502456
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of F-Box protein p45(SKP2) expression and stabilization of cyclin-dependent kinase inhibitor p27(KIP1) in vitamin D analog-treated cancer cells.
    Lin R; Wang TT; Miller WH; White JH
    Endocrinology; 2003 Mar; 144(3):749-53. PubMed ID: 12586749
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Skp2-mediated p27(Kip1) degradation during S/G2 phase progression of adipocyte hyperplasia.
    Auld CA; Fernandes KM; Morrison RF
    J Cell Physiol; 2007 Apr; 211(1):101-11. PubMed ID: 17096381
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells.
    Koga H; Harada M; Ohtsubo M; Shishido S; Kumemura H; Hanada S; Taniguchi E; Yamashita K; Kumashiro R; Ueno T; Sata M
    Hepatology; 2003 May; 37(5):1086-96. PubMed ID: 12717389
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bortezomib (Velcade) induces p27Kip1 expression through S-phase kinase protein 2 degradation in colorectal cancer.
    Uddin S; Ahmed M; Bavi P; El-Sayed R; Al-Sanea N; AbdulJabbar A; Ashari LH; Alhomoud S; Al-Dayel F; Hussain AR; Al-Kuraya KS
    Cancer Res; 2008 May; 68(9):3379-88. PubMed ID: 18451165
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proteomic identification of the oncoprotein STAT3 as a target of a novel Skp1 inhibitor.
    Cheng X; Liu YQ; Wang GZ; Yang LN; Lu YZ; Li XC; Zhou B; Qu LW; Wang XL; Cheng YX; Liu J; Tao SC; Zhou GB
    Oncotarget; 2017 Jan; 8(2):2681-2693. PubMed ID: 27835873
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel roles of Skp2 E3 ligase in cellular senescence, cancer progression, and metastasis.
    Wang G; Chan CH; Gao Y; Lin HK
    Chin J Cancer; 2012 Apr; 31(4):169-77. PubMed ID: 22200179
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2).
    Mamillapalli R; Gavrilova N; Mihaylova VT; Tsvetkov LM; Wu H; Zhang H; Sun H
    Curr Biol; 2001 Feb; 11(4):263-7. PubMed ID: 11250155
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The SKP2 E3 ligase regulates basal homeostasis and stress-induced regeneration of HSCs.
    Rodriguez S; Wang L; Mumaw C; Srour EF; Lo Celso C; Nakayama K; Carlesso N
    Blood; 2011 Jun; 117(24):6509-19. PubMed ID: 21502543
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanisms in cardiac fibroblast growth: an obligate role for Skp2 and FOXO3a in ERK1/2 MAPK-dependent regulation of p27kip1.
    Pramod S; Shivakumar K
    Am J Physiol Heart Circ Physiol; 2014 Mar; 306(6):H844-55. PubMed ID: 24441545
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of S-phase kinase-associated protein 2 (Skp2) reprograms and converts diabetogenic T cells to Foxp3+ regulatory T cells.
    Wang D; Qin H; Du W; Shen YW; Lee WH; Riggs AD; Liu CP
    Proc Natl Acad Sci U S A; 2012 Jun; 109(24):9493-8. PubMed ID: 22645357
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Early mitotic inhibitor-1, an anaphase-promoting complex/cyclosome inhibitor, can control tumor cell proliferation in hepatocellular carcinoma: correlation with Skp2 stability and degradation of p27(Kip1).
    Zhao Y; Tang Q; Ni R; Huang X; Wang Y; Lu C; Shen A; Wang Y; Li C; Yuan Q; Chen H; Cheng C; He S
    Hum Pathol; 2013 Mar; 44(3):365-73. PubMed ID: 22995332
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.