BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 31776036)

  • 1. Synthesis of d-ring modified acid hydrazide derivatives of podophyllotoxin and their anticancer studies as Tubulin inhibiting agents.
    Nerella S; Kankala S; Paidakula S; Gavaji B
    Bioorg Chem; 2020 Jan; 94():103384. PubMed ID: 31776036
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors.
    Kamal A; Srinivasa Reddy T; Polepalli S; Shalini N; Reddy VG; Subba Rao AV; Jain N; Shankaraiah N
    Bioorg Med Chem; 2014 Oct; 22(19):5466-75. PubMed ID: 25131956
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, biological evaluation, and 3D-QSAR analysis of podophyllotoxin-dioxazole combination as tubulin targeting anticancer agents.
    Wang ZZ; Sun WX; Wang X; Zhang YH; Qiu HY; Qi JL; Pang YJ; Lu GH; Wang XM; Yu FG; Yang YH
    Chem Biol Drug Des; 2017 Aug; 90(2):236-243. PubMed ID: 28079286
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design and synthesis of piperazine acetate podophyllotoxin ester derivatives targeting tubulin depolymerization as new anticancer agents.
    Sun WX; Ji YJ; Wan Y; Han HW; Lin HY; Lu GH; Qi JL; Wang XM; Yang YH
    Bioorg Med Chem Lett; 2017 Sep; 27(17):4066-4074. PubMed ID: 28757065
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Investigation of podophyllotoxin esters as potential anticancer agents: synthesis, biological studies and tubulin inhibition properties.
    Shareef MA; Duscharla D; Ramasatyaveni G; Dhoke NR; Das A; Ummanni R; Srivastava AK
    Eur J Med Chem; 2015 Jan; 89():128-37. PubMed ID: 25462233
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of a series of podophyllotoxins derivatives as a class of potent antitubulin agents.
    Liu Y; Wei D; Zhao Y; Cheng W; Lu Y; Ma Y; Li X; Han C; Wei Y; Cao H; Zhao C
    Bioorg Med Chem; 2012 Nov; 20(21):6285-95. PubMed ID: 23022053
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of new 3-phenyl-1H-indole-2-carbohydrazide derivatives and their structure-activity relationships as potent tubulin inhibitors and anticancer agents: A combined in silico, in vitro and synthetic study.
    Saruengkhanphasit R; Butkinaree C; Ornnork N; Lirdprapamongkol K; Niwetmarin W; Svasti J; Ruchirawat S; Eurtivong C
    Bioorg Chem; 2021 May; 110():104795. PubMed ID: 33730670
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of benzo[b]furo[3,4-e][1,4]diazepin-1-one derivatives as anti-cancer agents.
    Malayeri SO; Tayarani-Najaran Z; Behbahani FS; Rashidi R; Delpazir S; Ghodsi R
    Bioorg Chem; 2018 Oct; 80():631-638. PubMed ID: 30041139
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design and Synthesis of Novel Podophyllotoxins Hybrids and the Effects of Different Functional Groups on Cytotoxicity.
    Yang Z; Zhou Z; Luo X; Luo X; Luo H; Luo L; Yang W
    Molecules; 2021 Dec; 27(1):. PubMed ID: 35011453
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of podophyllotoxin derivatives as selective antitumor agents.
    Wu GR; Xu B; Yang YQ; Zhang XY; Fang K; Ma T; Wang H; Xue NN; Chen M; Guo WB; Jia XH; Wang PL; Lei HM
    Eur J Med Chem; 2018 Jul; 155():183-196. PubMed ID: 29886322
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel Podophyllotoxin Derivatives as Potential Tubulin Inhibitors: Design, Synthesis, and Antiproliferative Activity Evaluation.
    Han HW; Lin HY; He DL; Ren Y; Sun WX; Liang L; Du MH; Li DC; Chu YC; Yang MK; Wang XM; Yang YH
    Chem Biodivers; 2018 Nov; 15(11):e1800289. PubMed ID: 30194898
    [TBL] [Abstract][Full Text] [Related]  

  • 12. One-pot synthesis and biological evaluation of N-(aminosulfonyl)-4-podophyllotoxin carbamates as potential anticancer agents.
    Xu XH; Guan XW; Feng SL; Ma YZ; Chen SW; Hui L
    Bioorg Med Chem Lett; 2017 Jul; 27(13):2890-2894. PubMed ID: 28512026
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 4β-[(4-Alkyl)-1,2,3-triazol-1-yl] podophyllotoxins as anticancer compounds: design, synthesis and biological evaluation.
    Reddy DM; Srinivas J; Chashoo G; Saxena AK; Sampath Kumar HM
    Eur J Med Chem; 2011 Jun; 46(6):1983-91. PubMed ID: 21477899
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of 4beta-[(4-substituted)-1,2,3-triazol-1-yl]podophyllotoxins as potential anticancer agents.
    Reddy PB; Agrawal SK; Singh S; Bhat BA; Saxena AK; Kumar HM; Qazi GN
    Chem Biodivers; 2008 Sep; 5(9):1792-802. PubMed ID: 18816530
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of podophyllotoxin linked β-carboline congeners as potential anticancer agents and DNA topoisomerase II inhibitors.
    Sathish M; Kavitha B; Nayak VL; Tangella Y; Ajitha A; Nekkanti S; Alarifi A; Shankaraiah N; Nagesh N; Kamal A
    Eur J Med Chem; 2018 Jan; 144():557-571. PubMed ID: 29289881
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of novel potent cytotoxicy podophyllotoxin-naphthoquinone compounds via microwave-assited multicomponent domino reactions.
    Nguyen Thi QG; Le-Nhat-Thuy G; Dang Thi TA; Hoang Thi P; Nguyen Tuan A; Nguyen Thi TH; Nguyen TT; Nguyen Ha T; Hoang Mai H; Nguyen TV
    Bioorg Med Chem Lett; 2021 Apr; 37():127841. PubMed ID: 33556568
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tubulin inhibitors: Discovery of a new scaffold targeting extra-binding residues within the colchicine site through anchoring substituents properly adapted to their pocket by a semi-flexible linker.
    Maklad RM; AbdelHafez EMN; Abdelhamid D; Aly OM
    Bioorg Chem; 2020 Jun; 99():103767. PubMed ID: 32325332
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and cytotoxic activity on human cancer cells of carbamate derivatives of 4β-(1,2,3-triazol-1-yl)podophyllotoxin.
    Liu JF; Sang CY; Xu XH; Zhang LL; Yang X; Hui L; Zhang JB; Chen SW
    Eur J Med Chem; 2013 Jun; 64():621-8. PubMed ID: 23711769
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regioselective synthesis and in vitro anticancer activity of 4-aza-podophyllotoxin derivatives catalyzed by L-proline.
    Shi C; Wang J; Chen H; Shi D
    J Comb Chem; 2010 Jul; 12(4):430-4. PubMed ID: 20503973
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and anticancer activity of dimeric podophyllotoxin derivatives.
    Zi CT; Yang L; Xu FQ; Dong FW; Yang D; Li Y; Ding ZT; Zhou J; Jiang ZH; Hu JM
    Drug Des Devel Ther; 2018; 12():3393-3406. PubMed ID: 30349193
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.