BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

314 related articles for article (PubMed ID: 31782083)

  • 1. Eukaryotic initiation factor 4E is a novel effector of mTORC1 signaling pathway in cross talk with Mnk1.
    Batool A; Majeed ST; Aashaq S; Majeed R; Bhat NN; Andrabi KI
    Mol Cell Biochem; 2020 Feb; 465(1-2):13-26. PubMed ID: 31782083
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphorylation dynamics of eukaryotic initiation factor 4E binding protein 1 (4E-BP1) is discordant with its potential to interact with eukaryotic initiation factor 4E (eIF4E).
    Showkat M; Beigh MA; Bhat BB; Batool A; Andrabi KI
    Cell Signal; 2014 Oct; 26(10):2117-21. PubMed ID: 24975846
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Eukaryotic Initiation Factor 4E (eIF4E) sequestration mediates 4E-BP1 response to rapamycin.
    Batool A; Majeed ST; Aashaq S; Majeed R; Shah G; Nazir N; Andrabi KI
    Int J Biol Macromol; 2019 Mar; 125():651-659. PubMed ID: 30552925
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation.
    Wang X; Yue P; Chan CB; Ye K; Ueda T; Watanabe-Fukunaga R; Fukunaga R; Fu H; Khuri FR; Sun SY
    Mol Cell Biol; 2007 Nov; 27(21):7405-13. PubMed ID: 17724079
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function.
    Schalm SS; Fingar DC; Sabatini DM; Blenis J
    Curr Biol; 2003 May; 13(10):797-806. PubMed ID: 12747827
    [TBL] [Abstract][Full Text] [Related]  

  • 6. mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E.
    Fingar DC; Richardson CJ; Tee AR; Cheatham L; Tsou C; Blenis J
    Mol Cell Biol; 2004 Jan; 24(1):200-16. PubMed ID: 14673156
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells.
    Marzec M; Liu X; Wysocka M; Rook AH; Odum N; Wasik MA
    PLoS One; 2011; 6(9):e24849. PubMed ID: 21949767
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reciprocal signaling between mTORC1 and MNK2 controls cell growth and oncogenesis.
    Xie J; Shen K; Jones AT; Yang J; Tee AR; Shen MH; Yu M; Irani S; Wong D; Merrett JE; Lenchine RV; De Poi S; Jensen KB; Trim PJ; Snel MF; Kamei M; Martin SK; Fitter S; Tian S; Wang X; Butler LM; Zannettino ACW; Proud CG
    Cell Mol Life Sci; 2021 Jan; 78(1):249-270. PubMed ID: 32170339
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation.
    George A; Panda S; Kudmulwar D; Chhatbar SP; Nayak SC; Krishnan HH
    J Biol Chem; 2012 Feb; 287(7):5042-58. PubMed ID: 22184107
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MNK1 pathway activity maintains protein synthesis in rapalog-treated gliomas.
    Grzmil M; Huber RM; Hess D; Frank S; Hynx D; Moncayo G; Klein D; Merlo A; Hemmings BA
    J Clin Invest; 2014 Feb; 124(2):742-54. PubMed ID: 24401275
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The androgen receptor is a negative regulator of eIF4E phosphorylation at S209: implications for the use of mTOR inhibitors in advanced prostate cancer.
    D'Abronzo LS; Bose S; Crapuchettes ME; Beggs RE; Vinall RL; Tepper CG; Siddiqui S; Mudryj M; Melgoza FU; Durbin-Johnson BP; deVere White RW; Ghosh PM
    Oncogene; 2017 Nov; 36(46):6359-6373. PubMed ID: 28745319
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins.
    Wang X; Beugnet A; Murakami M; Yamanaka S; Proud CG
    Mol Cell Biol; 2005 Apr; 25(7):2558-72. PubMed ID: 15767663
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dual inhibition by S6K1 and Elf4E is essential for controlling cellular growth and invasion in bladder cancer.
    Kyou Kwon J; Kim SJ; Hoon Kim J; Mee Lee K; Ho Chang I
    Urol Oncol; 2014 Jan; 32(1):51.e27-35. PubMed ID: 24239466
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of eukaryotic initiation factor 4E (eIF4E) phosphorylation by mitogen-activated protein kinase occurs through modulation of Mnk1-eIF4G interaction.
    Shveygert M; Kaiser C; Bradrick SS; Gromeier M
    Mol Cell Biol; 2010 Nov; 30(21):5160-7. PubMed ID: 20823271
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulatory effects of a Mnk2-eIF4E feedback loop during mTORC1 targeting of human medulloblastoma cells.
    Eckerdt F; Beauchamp E; Bell J; Iqbal A; Su B; Fukunaga R; Lulla RR; Goldman S; Platanias LC
    Oncotarget; 2014 Sep; 5(18):8442-51. PubMed ID: 25193863
    [TBL] [Abstract][Full Text] [Related]  

  • 16. eIF4E-Overexpression imparts perillyl alcohol and rapamycin-mediated regulation of telomerase reverse transcriptase.
    Sundin T; Peffley D; Hentosh P
    Exp Cell Res; 2013 Aug; 319(13):2103-2112. PubMed ID: 23747720
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lost in translation: a neglected mTOR target for lymphangioleiomyomatosis.
    Evans JF; McCormack FX; Sonenberg N; Krymskaya VP
    Eur Respir Rev; 2023 Sep; 32(169):. PubMed ID: 37758276
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Overexpressed eIF4E is functionally active in surgical margins of head and neck cancer patients via activation of the Akt/mammalian target of rapamycin pathway.
    Nathan CO; Amirghahari N; Abreo F; Rong X; Caldito G; Jones ML; Zhou H; Smith M; Kimberly D; Glass J
    Clin Cancer Res; 2004 Sep; 10(17):5820-7. PubMed ID: 15355912
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Intestinal cell kinase, a MAP kinase-related kinase, regulates proliferation and G1 cell cycle progression of intestinal epithelial cells.
    Fu Z; Kim J; Vidrich A; Sturgill TW; Cohn SM
    Am J Physiol Gastrointest Liver Physiol; 2009 Oct; 297(4):G632-40. PubMed ID: 19696144
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The translation regulatory subunit eIF3f controls the kinase-dependent mTOR signaling required for muscle differentiation and hypertrophy in mouse.
    Csibi A; Cornille K; Leibovitch MP; Poupon A; Tintignac LA; Sanchez AM; Leibovitch SA
    PLoS One; 2010 Feb; 5(2):e8994. PubMed ID: 20126553
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.