123 related articles for article (PubMed ID: 31784322)
1. Discovery of pyrazolone spirocyclohexadienone derivatives with potent antitumor activity.
Wang L; Yang Z; Ni T; Shi W; Guo Y; Li K; Shi A; Wu S; Sheng C
Bioorg Med Chem Lett; 2020 Jan; 30(1):126662. PubMed ID: 31784322
[TBL] [Abstract][Full Text] [Related]
2. Novel spiropyrazolone antitumor scaffold with potent activity: Design, synthesis and structure-activity relationship.
Wu S; Li Y; Xu G; Chen S; Zhang Y; Liu N; Dong G; Miao C; Su H; Zhang W; Sheng C
Eur J Med Chem; 2016 Jun; 115():141-7. PubMed ID: 27016707
[TBL] [Abstract][Full Text] [Related]
3. Pyrazolone structural motif in medicinal chemistry: Retrospect and prospect.
Zhao Z; Dai X; Li C; Wang X; Tian J; Feng Y; Xie J; Ma C; Nie Z; Fan P; Qian M; He X; Wu S; Zhang Y; Zheng X
Eur J Med Chem; 2020 Jan; 186():111893. PubMed ID: 31761383
[TBL] [Abstract][Full Text] [Related]
4. A cell-based screen for anticancer activity of 13 pyrazolone derivatives.
Wang XH; Wang XK; Liang YJ; Shi Z; Zhang JY; Chen LM; Fu LW
Chin J Cancer; 2010 Dec; 29(12):980-7. PubMed ID: 21114917
[TBL] [Abstract][Full Text] [Related]
5. Stereoselective Assembly of Multifunctional Spirocyclohexene Pyrazolones That Induce Autophagy-Dependent Apoptosis in Colorectal Cancer Cells.
Li X; Chen FY; Kang JW; Zhou J; Peng C; Huang W; Zhou MK; He G; Han B
J Org Chem; 2019 Jul; 84(14):9138-9150. PubMed ID: 31267754
[TBL] [Abstract][Full Text] [Related]
6. Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-
Kurasawa O; Miyazaki T; Homma M; Oguro Y; Imada T; Uchiyama N; Iwai K; Yamamoto Y; Ohori M; Hara H; Sugimoto H; Iwata K; Skene R; Hoffman I; Ohashi A; Nomura T; Cho N
J Med Chem; 2020 Feb; 63(3):1084-1104. PubMed ID: 31895562
[TBL] [Abstract][Full Text] [Related]
7. Pyrazolone-fused combretastatins and their precursors: synthesis, cytotoxicity, antitubulin activity and molecular modeling studies.
Burja B; Cimbora-Zovko T; Tomić S; Jelusić T; Kocevar M; Polanc S; Osmak M
Bioorg Med Chem; 2010 Apr; 18(7):2375-87. PubMed ID: 20338766
[TBL] [Abstract][Full Text] [Related]
8. Tertiary Amine Pyrazolones and Their Salts as Inhibitors of Mutant Superoxide Dismutase 1-Dependent Protein Aggregation for the Treatment of Amyotrophic Lateral Sclerosis.
Zhang Y; Zhao KT; Fox SG; Kim J; Kirsch DR; Ferrante RJ; Morimoto RI; Silverman RB
J Med Chem; 2015 Aug; 58(15):5942-9. PubMed ID: 26186011
[TBL] [Abstract][Full Text] [Related]
9. Discovery of novel pyrimidine-based benzothiazole derivatives as potent cyclin-dependent kinase 2 inhibitors with anticancer activity.
Diao PC; Lin WY; Jian XE; Li YH; You WW; Zhao PL
Eur J Med Chem; 2019 Oct; 179():196-207. PubMed ID: 31254921
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis and biological evaluation of novel thieno[3,2-d]pyrimidine and quinazoline derivatives as potent antitumor agents.
Hu H; Dong Y; Li M; Wang R; Zhang X; Gong P; Zhao Y
Bioorg Chem; 2019 Sep; 90():103086. PubMed ID: 31280016
[TBL] [Abstract][Full Text] [Related]
11. Pyrazolone incorporating bipyridyl metallointercalators as effective DNA, protein and lung cancer targets: Synthesis, characterization and in vitro biocidal evaluation.
Vyas KM; Devkar RV; Prajapati A; Jadeja RN
Chem Biol Interact; 2015 Oct; 240():250-66. PubMed ID: 26341650
[TBL] [Abstract][Full Text] [Related]
12. Reduction of cisplatin-induced nephrotoxicity by pyrazolone compounds, derivatives of tetrahydroindazolonedicarboxylic acid.
Marijic VF; Makarevic J; Stojkovic R; Kalinic L; Katalenic D; Radacic M
Methods Find Exp Clin Pharmacol; 2008 Nov; 30(9):675-80. PubMed ID: 19229375
[TBL] [Abstract][Full Text] [Related]
13. A novel pyrazolone-based derivative induces apoptosis in human esophageal cells via reactive oxygen species (ROS) generation and caspase-dependent mitochondria-mediated pathway.
Zhao J; Zhang L; Li J; Wu T; Wang M; Xu G; Zhang F; Liu L; Yang J; Sun S
Chem Biol Interact; 2015 Apr; 231():1-9. PubMed ID: 25684395
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis and in vitro anticancer activity of novel quinoline and oxadiazole derivatives of ursolic acid.
Gu W; Jin XY; Li DD; Wang SF; Tao XB; Chen H
Bioorg Med Chem Lett; 2017 Sep; 27(17):4128-4132. PubMed ID: 28733083
[TBL] [Abstract][Full Text] [Related]
15. Discovery of novel diaryl urea derivatives bearing a triazole moiety as potential antitumor agents.
Qin M; Yan S; Wang L; Zhang H; Zhao Y; Wu S; Wu D; Gong P
Eur J Med Chem; 2016 Jun; 115():1-13. PubMed ID: 26991938
[TBL] [Abstract][Full Text] [Related]
16. Synthesis, anticancer activity and effects on cell cycle profile and apoptosis of novel thieno[2,3-d]pyrimidine and thieno[3,2-e] triazolo[4,3-c]pyrimidine derivatives.
Kandeel MM; Refaat HM; Kassab AE; Shahin IG; Abdelghany TM
Eur J Med Chem; 2015 Jan; 90():620-32. PubMed ID: 25499930
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis, biological evaluation and molecular docking study of novel thieno[3,2-d]pyrimidine derivatives as potent FAK inhibitors.
Wang R; Yu S; Zhao X; Chen Y; Yang B; Wu T; Hao C; Zhao D; Cheng M
Eur J Med Chem; 2020 Feb; 188():112024. PubMed ID: 31923858
[TBL] [Abstract][Full Text] [Related]
18. A Therapeutic Journey of 5-Pyrazolones as a Versatile Scaffold: A Review.
Sharma R; Chawla PA; Chawla V; Verma R; Nawal N; Gupta V
Mini Rev Med Chem; 2021; 21(13):1770-1795. PubMed ID: 33397258
[TBL] [Abstract][Full Text] [Related]
19. Discovery of novel 2-substituted-4-(2-fluorophenoxy) pyridine derivatives possessing pyrazolone and triazole moieties as dual c-Met/VEGFR-2 receptor tyrosine kinase inhibitors.
Gu W; Dai Y; Qiang H; Shi W; Liao C; Zhao F; Huang W; Qian H
Bioorg Chem; 2017 Jun; 72():116-122. PubMed ID: 28411406
[TBL] [Abstract][Full Text] [Related]
20. New series of antiprion compounds: pyrazolone derivatives have the potent activity of inhibiting protease-resistant prion protein accumulation.
Kimata A; Nakagawa H; Ohyama R; Fukuuchi T; Ohta S; Doh-ura K; Suzuki T; Miyata N
J Med Chem; 2007 Oct; 50(21):5053-6. PubMed ID: 17850126
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
