These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
13. Discovery of a selective M₄ positive allosteric modulator based on the 3-amino-thieno[2,3-b]pyridine-2-carboxamide scaffold: development of ML253, a potent and brain penetrant compound that is active in a preclinical model of schizophrenia. Le U; Melancon BJ; Bridges TM; Vinson PN; Utley TJ; Lamsal A; Rodriguez AL; Venable D; Sheffler DJ; Jones CK; Blobaum AL; Wood MR; Daniels JS; Conn PJ; Niswender CM; Lindsley CW; Hopkins CR Bioorg Med Chem Lett; 2013 Jan; 23(1):346-50. PubMed ID: 23177787 [TBL] [Abstract][Full Text] [Related]
14. Discovery, Optimization, and Biological Characterization of 2,3,6-Trisubstituted Pyridine-Containing M Schubert JW; Harrison ST; Mulhearn J; Gomez R; Tynebor R; Jones K; Bunda J; Hanney B; Wai JM; Cox C; McCauley JA; Sanders JM; Magliaro B; O'Brien J; Pajkovic N; Huszar Agrapides SL; Taylor A; Gotter A; Smith SM; Uslaner J; Browne S; Risso S; Egbertson M ChemMedChem; 2019 May; 14(9):943-951. PubMed ID: 30920765 [TBL] [Abstract][Full Text] [Related]
16. Development of a radioligand, [(3)H]LY2119620, to probe the human M(2) and M(4) muscarinic receptor allosteric binding sites. Schober DA; Croy CH; Xiao H; Christopoulos A; Felder CC Mol Pharmacol; 2014 Jul; 86(1):116-23. PubMed ID: 24807966 [TBL] [Abstract][Full Text] [Related]