BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 31800202)

  • 1. Three-Dimensional Structure of RNA Monomeric G-Quadruplex Containing ALS and FTD Related G4C2 Repeat and Its Binding with TMPyP4 Probed by Homology Modeling based on Experimental Constraints and Molecular Dynamics Simulations.
    Mulholland K; Sullivan HJ; Garner J; Cai J; Chen B; Wu C
    ACS Chem Neurosci; 2020 Jan; 11(1):57-75. PubMed ID: 31800202
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD.
    Zhou B; Liu C; Geng Y; Zhu G
    Sci Rep; 2015 Nov; 5():16673. PubMed ID: 26564809
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structure of parallel G-quadruplex formed by the two-repeat ALS- and FTD-related GGGGCC sequence.
    Geng Y; Liu C; Cai Q; Luo Z; Miao H; Shi X; Xu N; Fung CP; Choy TT; Yan B; Li N; Qian P; Zhou B; Zhu G
    Nucleic Acids Res; 2021 Jun; 49(10):5881-5890. PubMed ID: 34048588
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterizations of distinct parallel and antiparallel G-quadruplexes formed by two-repeat ALS and FTD related GGGGCC sequence.
    Zhou B; Geng Y; Liu C; Miao H; Ren Y; Xu N; Shi X; You Y; Lee T; Zhu G
    Sci Rep; 2018 Feb; 8(1):2366. PubMed ID: 29402965
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A synthetic Pur-based peptide binds and alters G-quadruplex secondary structure present in the expanded RNA repeat of C9orf72 ALS/FTD.
    Wortman MJ; Dagdanova AV; Clark AM; Godfrey EW; Pascal SM; Johnson EM; Daniel DC
    Biochim Biophys Acta Mol Cell Res; 2020 Jun; 1867(6):118674. PubMed ID: 32035967
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TMPyP4 porphyrin distorts RNA G-quadruplex structures of the disease-associated r(GGGGCC)n repeat of the C9orf72 gene and blocks interaction of RNA-binding proteins.
    Zamiri B; Reddy K; Macgregor RB; Pearson CE
    J Biol Chem; 2014 Feb; 289(8):4653-9. PubMed ID: 24371143
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Solution structure of a DNA quadruplex containing ALS and FTD related GGGGCC repeat stabilized by 8-bromodeoxyguanosine substitution.
    Brčić J; Plavec J
    Nucleic Acids Res; 2015 Sep; 43(17):8590-600. PubMed ID: 26253741
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thermodynamic and spectroscopic investigations of TMPyP4 association with guanine- and cytosine-rich DNA and RNA repeats of C9orf72.
    Alniss H; Zamiri B; Khalaj M; Pearson CE; Macgregor RB
    Biochem Biophys Res Commun; 2018 Jan; 495(4):2410-2417. PubMed ID: 29274339
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural insight into C9orf72 hexanucleotide repeat expansions: Towards new therapeutic targets in FTD-ALS.
    Kumar V; Kashav T; Islam A; Ahmad F; Hassan MI
    Neurochem Int; 2016 Nov; 100():11-20. PubMed ID: 27539655
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Formation of RNA G-wires by G
    Bose K; Maity A; Ngo KH; Vandana JJ; Shneider NA; Phan AT
    Biochem Biophys Res Commun; 2022 Jun; 610():113-118. PubMed ID: 35462091
    [TBL] [Abstract][Full Text] [Related]  

  • 11. C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes.
    Fratta P; Mizielinska S; Nicoll AJ; Zloh M; Fisher EM; Parkinson G; Isaacs AM
    Sci Rep; 2012; 2():1016. PubMed ID: 23264878
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ALS/FTD-Associated C9ORF72 Repeat RNA Promotes Phase Transitions In Vitro and in Cells.
    Fay MM; Anderson PJ; Ivanov P
    Cell Rep; 2017 Dec; 21(12):3573-3584. PubMed ID: 29262335
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ALS and FTD linked GGGGCC-repeat containing DNA oligonucleotide folds into two distinct G-quadruplexes.
    Brčić J; Plavec J
    Biochim Biophys Acta Gen Subj; 2017 May; 1861(5 Pt B):1237-1245. PubMed ID: 27856299
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural and Dynamical Characterization of DNA and RNA Quadruplexes Obtained from the GGGGCC and GGGCCT Hexanucleotide Repeats Associated with C9FTD/ALS and SCA36 Diseases.
    Zhang Y; Roland C; Sagui C
    ACS Chem Neurosci; 2018 May; 9(5):1104-1117. PubMed ID: 29281254
    [TBL] [Abstract][Full Text] [Related]  

  • 15. G-Quadruplexes Formation by the
    Zhang Y; Huang J; Yu K; Cui X
    Molecules; 2023 Jun; 28(12):. PubMed ID: 37375224
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The porphyrin TMPyP4 inhibits elongation during the noncanonical translation of the FTLD/ALS-associated GGGGCC repeat in the C9orf72 gene.
    Mori K; Gotoh S; Yamashita T; Uozumi R; Kawabe Y; Tagami S; Kamp F; Nuscher B; Edbauer D; Haass C; Nagai Y; Ikeda M
    J Biol Chem; 2021 Oct; 297(4):101120. PubMed ID: 34450161
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NMR structure of a G-quadruplex formed by four d(G4C2) repeats: insights into structural polymorphism.
    Brcic J; Plavec J
    Nucleic Acids Res; 2018 Nov; 46(21):11605-11617. PubMed ID: 30277522
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conformational dynamics of RNA G4C2 and G2C4 repeat expansions causing ALS/FTD using NMR and molecular dynamics studies.
    Taghavi A; Baisden JT; Childs-Disney JL; Yildirim I; Disney MD
    Nucleic Acids Res; 2023 Jun; 51(11):5325-5340. PubMed ID: 37216594
    [TBL] [Abstract][Full Text] [Related]  

  • 19. C9orf72 and triplet repeat disorder RNAs: G-quadruplex formation, binding to PRC2 and implications for disease mechanisms.
    Wang X; Goodrich KJ; Conlon EG; Gao J; Erbse AH; Manley JL; Cech TR
    RNA; 2019 Aug; 25(8):935-947. PubMed ID: 31048495
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural Features of Small Molecules Targeting the RNA Repeat Expansion That Causes Genetically Defined ALS/FTD.
    Ursu A; Wang KW; Bush JA; Choudhary S; Chen JL; Baisden JT; Zhang YJ; Gendron TF; Petrucelli L; Yildirim I; Disney MD
    ACS Chem Biol; 2020 Dec; 15(12):3112-3123. PubMed ID: 33196168
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.