BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

108 related articles for article (PubMed ID: 31805259)

  • 1. Relax, Don't RAN Translate It.
    Wilson KM; Muralidharan B; Isaacs AM
    Neuron; 2019 Dec; 104(5):827-829. PubMed ID: 31805259
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation.
    Cheng W; Wang S; Zhang Z; Morgens DW; Hayes LR; Lee S; Portz B; Xie Y; Nguyen BV; Haney MS; Yan S; Dong D; Coyne AN; Yang J; Xian F; Cleveland DW; Qiu Z; Rothstein JD; Shorter J; Gao FB; Bassik MC; Sun S
    Neuron; 2019 Dec; 104(5):885-898.e8. PubMed ID: 31587919
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The RNA helicase DHX36-G4R1 modulates C9orf72 GGGGCC hexanucleotide repeat-associated translation.
    Tseng YJ; Sandwith SN; Green KM; Chambers AE; Krans A; Raimer HM; Sharlow ME; Reisinger MA; Richardson AE; Routh ED; Smaldino MA; Wang YH; Vaughn JP; Todd PK; Smaldino PJ
    J Biol Chem; 2021 Aug; 297(2):100914. PubMed ID: 34174288
    [TBL] [Abstract][Full Text] [Related]  

  • 4. All in the Family: Repeats and ALS/FTD.
    Pattamatta A; Cleary JD; Ranum LPW
    Trends Neurosci; 2018 May; 41(5):247-250. PubMed ID: 29703376
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TMPyP4 porphyrin distorts RNA G-quadruplex structures of the disease-associated r(GGGGCC)n repeat of the C9orf72 gene and blocks interaction of RNA-binding proteins.
    Zamiri B; Reddy K; Macgregor RB; Pearson CE
    J Biol Chem; 2014 Feb; 289(8):4653-9. PubMed ID: 24371143
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Helicase Unwinds Hexanucleotide Repeat RNA G-Quadruplexes and Facilitates Repeat-Associated Non-AUG Translation.
    Liu H; Lu YN; Paul T; Periz G; Banco MT; Ferré-D'Amaré AR; Rothstein JD; Hayes LR; Myong S; Wang J
    J Am Chem Soc; 2021 May; 143(19):7368-7379. PubMed ID: 33855846
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [Impact of C9orf72 on Japanese Patients with Amytrophic Lateral Sclerosis (ALS)/Frontotemporal Dementia (FTD)].
    Tomiyama H
    Brain Nerve; 2019 Nov; 71(11):1190-1208. PubMed ID: 31722305
    [TBL] [Abstract][Full Text] [Related]  

  • 8. C9ORF72 GGGGCC repeat-associated non-AUG translation is upregulated by stress through eIF2α phosphorylation.
    Cheng W; Wang S; Mestre AA; Fu C; Makarem A; Xian F; Hayes LR; Lopez-Gonzalez R; Drenner K; Jiang J; Cleveland DW; Sun S
    Nat Commun; 2018 Jan; 9(1):51. PubMed ID: 29302060
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The clinical and pathological phenotype of C9ORF72 hexanucleotide repeat expansions.
    Simón-Sánchez J; Dopper EG; Cohn-Hokke PE; Hukema RK; Nicolaou N; Seelaar H; de Graaf JR; de Koning I; van Schoor NM; Deeg DJ; Smits M; Raaphorst J; van den Berg LH; Schelhaas HJ; De Die-Smulders CE; Majoor-Krakauer D; Rozemuller AJ; Willemsen R; Pijnenburg YA; Heutink P; van Swieten JC
    Brain; 2012 Mar; 135(Pt 3):723-35. PubMed ID: 22300876
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Measuring Repeat-Associated Non-AUG (RAN) Translation.
    Wang S; Sun S
    Methods Mol Biol; 2022; 2428():113-132. PubMed ID: 35171477
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders.
    Boivin M; Pfister V; Gaucherot A; Ruffenach F; Negroni L; Sellier C; Charlet-Berguerand N
    EMBO J; 2020 Feb; 39(4):e100574. PubMed ID: 31930538
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Amyotrophic lateral sclerosis/frontotemporal dementia with predominant manifestations of obsessive-compulsive disorder associated to GGGGCC expansion of the c9orf72 gene.
    Calvo A; Moglia C; Canosa A; Cistaro A; Valentini C; Carrara G; Soldano E; Ilardi A; Bersano E; Bertuzzo D; Brunetti M; Ossola I; Restagno G; Chiò A
    J Neurol; 2012 Dec; 259(12):2723-5. PubMed ID: 22918453
    [No Abstract]   [Full Text] [Related]  

  • 13. Insights into the pathogenic mechanisms of Chromosome 9 open reading frame 72 (C9orf72) repeat expansions.
    Todd TW; Petrucelli L
    J Neurochem; 2016 Aug; 138 Suppl 1():145-62. PubMed ID: 27016280
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RANTing about C9orf72.
    Lashley T; Hardy J; Isaacs AM
    Neuron; 2013 Feb; 77(4):597-8. PubMed ID: 23439112
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Repeat-associated non-AUG (RAN) translation mechanisms are running into focus for GGGGCC-repeat associated ALS/FTD.
    Goodman LD; Bonini NM
    Prog Neurobiol; 2019 Dec; 183():101697. PubMed ID: 31550516
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dual-gRNA approach with limited off-target effect corrects C9ORF72 repeat expansion in vivo.
    Piao X; Meng D; Zhang X; Song Q; Lv H; Jia Y
    Sci Rep; 2022 Apr; 12(1):5672. PubMed ID: 35383205
    [TBL] [Abstract][Full Text] [Related]  

  • 17. New developments in RAN translation: insights from multiple diseases.
    Cleary JD; Ranum LP
    Curr Opin Genet Dev; 2017 Jun; 44():125-134. PubMed ID: 28365506
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reconstitution of C9orf72 GGGGCC repeat-associated non-AUG translation with purified human translation factors.
    Ito H; Machida K; Hasumi M; Ueyama M; Nagai Y; Imataka H; Taguchi H
    Sci Rep; 2023 Dec; 13(1):22826. PubMed ID: 38129650
    [TBL] [Abstract][Full Text] [Related]  

  • 19. There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALS.
    Gitler AD; Tsuiji H
    Brain Res; 2016 Sep; 1647():19-29. PubMed ID: 27059391
    [TBL] [Abstract][Full Text] [Related]  

  • 20. RAN translation-What makes it run?
    Green KM; Linsalata AE; Todd PK
    Brain Res; 2016 Sep; 1647():30-42. PubMed ID: 27060770
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.