These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

387 related articles for article (PubMed ID: 31812544)

  • 1. Review of the anti-inflammatory effect of SIRT1 and SIRT2 modulators on neurodegenerative diseases.
    Zhang Y; Anoopkumar-Dukie S; Arora D; Davey AK
    Eur J Pharmacol; 2020 Jan; 867():172847. PubMed ID: 31812544
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SIRT1 and SIRT2: emerging targets in neurodegeneration.
    Donmez G; Outeiro TF
    EMBO Mol Med; 2013 Mar; 5(3):344-52. PubMed ID: 23417962
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tissue-specific deregulation of selected HDACs characterizes ALS progression in mouse models: pharmacological characterization of SIRT1 and SIRT2 pathways.
    Valle C; Salvatori I; Gerbino V; Rossi S; Palamiuc L; René F; Carrì MT
    Cell Death Dis; 2014 Jun; 5(6):e1296. PubMed ID: 24946089
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential sirtuin expression patterns in amyotrophic lateral sclerosis (ALS) postmortem tissue: neuroprotective or neurotoxic properties of sirtuins in ALS?
    Körner S; Böselt S; Thau N; Rath KJ; Dengler R; Petri S
    Neurodegener Dis; 2013; 11(3):141-52. PubMed ID: 22796962
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression of sirtuin 1 and 2 is associated with poor prognosis in non-small cell lung cancer patients.
    Grbesa I; Pajares MJ; Martínez-Terroba E; Agorreta J; Mikecin AM; Larráyoz M; Idoate MA; Gall-Troselj K; Pio R; Montuenga LM
    PLoS One; 2015; 10(4):e0124670. PubMed ID: 25915617
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SIRT1 and SIRT2 Modulators: Potential Anti-Inflammatory Treatment for Depression?
    Zhang Y; Anoopkumar-Dukie S; Davey AK
    Biomolecules; 2021 Feb; 11(3):. PubMed ID: 33669121
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and structure-activity relationship studies of novel sirtuin 2 (SIRT2) inhibitors with a benzamide skeleton.
    Sakai T; Matsumoto Y; Ishikawa M; Sugita K; Hashimoto Y; Wakai N; Kitao A; Morishita E; Toyoshima C; Hayashi T; Akiyama T
    Bioorg Med Chem; 2015 Jan; 23(2):328-39. PubMed ID: 25515955
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression/localization patterns of sirtuins (SIRT1, SIRT2, and SIRT7) during progression of cervical cancer and effects of sirtuin inhibitors on growth of cervical cancer cells.
    Singh S; Kumar PU; Thakur S; Kiran S; Sen B; Sharma S; Rao VV; Poongothai AR; Ramakrishna G
    Tumour Biol; 2015 Aug; 36(8):6159-71. PubMed ID: 25794641
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SIRT1 activation with neuroheal is neuroprotective but SIRT2 inhibition with AK7 is detrimental for disconnected motoneurons.
    Romeo-Guitart D; Leiva-Rodríguez T; Espinosa-Alcantud M; Sima N; Vaquero A; Domínguez-Martín H; Ruano D; Casas C
    Cell Death Dis; 2018 May; 9(5):531. PubMed ID: 29748539
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis, in-vitro evaluation and molecular docking studies of novel indole derivatives as inhibitors of SIRT1 and SIRT2.
    Manjula R; Gokhale N; Unni S; Deshmukh P; Reddyrajula R; Srinivas Bharath MM; Dalimba U; Padmanabhan B
    Bioorg Chem; 2019 Nov; 92():103281. PubMed ID: 31561106
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cooperative effects of SIRT1 and SIRT2 on APP acetylation.
    Li N; Bai N; Zhao X; Cheng R; Wu X; Jiang B; Li X; Xue M; Xu H; Guo Q; Guo W; Ma M; Cao S; Feng Y; Song X; Wang Z; Zhang X; Zou Y; Wang D; Liu H; Cao L
    Aging Cell; 2023 Oct; 22(10):e13967. PubMed ID: 37602729
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SIRT1 and SIRT2 modulators reduce LPS-induced inflammation in HAPI microglial cells and protect SH-SY5Y neuronal cells in vitro.
    Zhang Y; Anoopkumar-Dukie S; Mallik SB; Davey AK
    J Neural Transm (Vienna); 2021 May; 128(5):631-644. PubMed ID: 33821324
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of bicyclic pyrazoles as class III histone deacetylase SIRT1 and SIRT2 inhibitors.
    Therrien E; Larouche G; Nguyen N; Rahil J; Lemieux AM; Li Z; Fournel M; Yan TP; Landry AJ; Lefebvre S; Wang JJ; MacBeth K; Heise C; Nguyen A; Besterman JM; Déziel R; Wahhab A
    Bioorg Med Chem Lett; 2015 Jun; 25(12):2514-8. PubMed ID: 25971769
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Beneficial Roles of SIRT1 in Neuroinflammation-Related Diseases.
    Jiao F; Gong Z
    Oxid Med Cell Longev; 2020; 2020():6782872. PubMed ID: 33014276
    [TBL] [Abstract][Full Text] [Related]  

  • 15. SIRT1 is a novel regulator of key pathways of human labor.
    Lappas M; Mitton A; Lim R; Barker G; Riley C; Permezel M
    Biol Reprod; 2011 Jan; 84(1):167-78. PubMed ID: 20844277
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Recent advances in inhibitors of sirtuin1/2: an update and perspective.
    Zhou Z; Ma T; Zhu Q; Xu Y; Zha X
    Future Med Chem; 2018 Apr; 10(8):907-934. PubMed ID: 29642711
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The discovery of a highly selective 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one SIRT2 inhibitor that is neuroprotective in an in vitro Parkinson's disease model.
    Di Fruscia P; Zacharioudakis E; Liu C; Moniot S; Laohasinnarong S; Khongkow M; Harrison IF; Koltsida K; Reynolds CR; Schmidtkunz K; Jung M; Chapman KL; Steegborn C; Dexter DT; Sternberg MJ; Lam EW; Fuchter MJ
    ChemMedChem; 2015 Jan; 10(1):69-82. PubMed ID: 25395356
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SIRT2 in age-related neurodegenerative disorders.
    Fourcade S; Outeiro TF; Pujol A
    Aging (Albany NY); 2018 Mar; 10(3):295-296. PubMed ID: 29514133
    [No Abstract]   [Full Text] [Related]  

  • 19. Finding Potent Sirt Inhibitor in Coffee: Isolation, Confirmation and Synthesis of Javamide-II (N-Caffeoyltryptophan) as Sirt1/2 Inhibitor.
    Park JB
    PLoS One; 2016; 11(3):e0150392. PubMed ID: 26986569
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functional characterization of NAD dependent de-acetylases SIRT1 and SIRT2 in B-Cell Chronic Lymphocytic Leukemia (CLL).
    Bhalla S; Gordon LI
    Cancer Biol Ther; 2016; 17(3):300-9. PubMed ID: 26794150
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.