246 related articles for article (PubMed ID: 31812695)
1. Acidosis-induced metabolic reprogramming in tumor cells enhances the anti-proliferative activity of the PDK inhibitor dichloroacetate.
Schoonjans CA; Joudiou N; Brusa D; Corbet C; Feron O; Gallez B
Cancer Lett; 2020 Feb; 470():18-28. PubMed ID: 31812695
[TBL] [Abstract][Full Text] [Related]
2. Impact of Sodium Dichloroacetate Alone and in Combination Therapies on Lung Tumor Growth and Metastasis.
Al-Azawi A; Sulaiman S; Arafat K; Yasin J; Nemmar A; Attoub S
Int J Mol Sci; 2021 Nov; 22(22):. PubMed ID: 34830434
[TBL] [Abstract][Full Text] [Related]
3. Multi-modality imaging to assess metabolic response to dichloroacetate treatment in tumor models.
Neveu MA; De Preter G; Joudiou N; Bol A; Brender JR; Saito K; Kishimoto S; Grégoire V; Jordan BF; Krishna MC; Feron O; Gallez B
Oncotarget; 2016 Dec; 7(49):81741-81749. PubMed ID: 28082726
[TBL] [Abstract][Full Text] [Related]
4. Natural Product Albiziabioside A Conjugated with Pyruvate Dehydrogenase Kinase Inhibitor Dichloroacetate To Induce Apoptosis-Ferroptosis-M2-TAMs Polarization for Combined Cancer Therapy.
Wei G; Sun J; Luan W; Hou Z; Wang S; Cui S; Cheng M; Liu Y
J Med Chem; 2019 Oct; 62(19):8760-8772. PubMed ID: 31509699
[TBL] [Abstract][Full Text] [Related]
5. Dichloroacetate and Pyruvate Metabolism: Pyruvate Dehydrogenase Kinases as Targets Worth Investigating for Effective Therapy of Toxoplasmosis.
Ferrarini MG; Nisimura LM; Girard RMBM; Alencar MB; Fragoso MSI; Araújo-Silva CA; Veiga AA; Abud APR; Nardelli SC; Vommaro RC; Silber AM; France-Sagot M; Ávila AR
mSphere; 2021 Jan; 6(1):. PubMed ID: 33408226
[TBL] [Abstract][Full Text] [Related]
6. Dichloroacetate enhances apoptotic cell death via oxidative damage and attenuates lactate production in metformin-treated breast cancer cells.
Haugrud AB; Zhuang Y; Coppock JD; Miskimins WK
Breast Cancer Res Treat; 2014 Oct; 147(3):539-50. PubMed ID: 25212175
[TBL] [Abstract][Full Text] [Related]
7. Antitumor and chemosensitizing action of dichloroacetate implicates modulation of tumor microenvironment: a role of reorganized glucose metabolism, cell survival regulation and macrophage differentiation.
Kumar A; Kant S; Singh SM
Toxicol Appl Pharmacol; 2013 Nov; 273(1):196-208. PubMed ID: 24051182
[TBL] [Abstract][Full Text] [Related]
8. Sensitization of metformin-cytotoxicity by dichloroacetate via reprogramming glucose metabolism in cancer cells.
Choi YW; Lim IK
Cancer Lett; 2014 May; 346(2):300-8. PubMed ID: 24480191
[TBL] [Abstract][Full Text] [Related]
9. Suppression of Pyruvate Dehydrogenase Kinase by Dichloroacetate in Cancer and Skeletal Muscle Cells Is Isoform Specific and Partially Independent of HIF-1α.
Škorja Milić N; Dolinar K; Miš K; Matkovič U; Bizjak M; Pavlin M; Podbregar M; Pirkmajer S
Int J Mol Sci; 2021 Aug; 22(16):. PubMed ID: 34445316
[TBL] [Abstract][Full Text] [Related]
10. Metabolic Modulation of Clear-cell Renal Cell Carcinoma with Dichloroacetate, an Inhibitor of Pyruvate Dehydrogenase Kinase.
Kinnaird A; Dromparis P; Saleme B; Gurtu V; Watson K; Paulin R; Zervopoulos S; Stenson T; Sutendra G; Pink DB; Carmine-Simmen K; Moore R; Lewis JD; Michelakis ED
Eur Urol; 2016 Apr; 69(4):734-744. PubMed ID: 26433571
[TBL] [Abstract][Full Text] [Related]
11. Dichloroacetate Affects Mitochondrial Function and Stemness-Associated Properties in Pancreatic Cancer Cell Lines.
Tataranni T; Agriesti F; Pacelli C; Ruggieri V; Laurenzana I; Mazzoccoli C; Sala GD; Panebianco C; Pazienza V; Capitanio N; Piccoli C
Cells; 2019 May; 8(5):. PubMed ID: 31109089
[TBL] [Abstract][Full Text] [Related]
12. Dichloroacetate enhances adriamycin-induced hepatoma cell toxicity in vitro and in vivo by increasing reactive oxygen species levels.
Dai Y; Xiong X; Huang G; Liu J; Sheng S; Wang H; Qin W
PLoS One; 2014; 9(4):e92962. PubMed ID: 24728083
[TBL] [Abstract][Full Text] [Related]
13. Combinatorial Effect of DCA and Let-7a on Triple-Negative MDA-MB-231 Cells: A Metabolic Approach of Treatment.
Sharma P; Singh S
Integr Cancer Ther; 2020; 19():1534735420911437. PubMed ID: 32248711
[TBL] [Abstract][Full Text] [Related]
14. Metformin enhances antitumor action of sodium dichloroacetate against glioma C6.
Kolesnik DL; Pyaskovskaya ON; Yurchenko OV; Solyanik GI
Exp Oncol; 2019 Jun; 41(2):123-129. PubMed ID: 31262158
[TBL] [Abstract][Full Text] [Related]
15. Targeting aerobic glycolysis by dichloroacetate improves Newcastle disease virus-mediated viro-immunotherapy in hepatocellular carcinoma.
Meng G; Li B; Chen A; Zheng M; Xu T; Zhang H; Dong J; Wu J; Yu D; Wei J
Br J Cancer; 2020 Jan; 122(1):111-120. PubMed ID: 31819179
[TBL] [Abstract][Full Text] [Related]
16. Synergistic antitumor effect of dichloroacetate in combination with 5-fluorouracil in colorectal cancer.
Tong J; Xie G; He J; Li J; Pan F; Liang H
J Biomed Biotechnol; 2011; 2011():740564. PubMed ID: 21403907
[TBL] [Abstract][Full Text] [Related]
17. Targeting of two aspects of metabolism in breast cancer treatment.
Gang BP; Dilda PJ; Hogg PJ; Blackburn AC
Cancer Biol Ther; 2014; 15(11):1533-41. PubMed ID: 25482950
[TBL] [Abstract][Full Text] [Related]
18. Targeted reversal and phosphorescence lifetime imaging of cancer cell metabolism via a theranostic rhenium(I)-DCA conjugate.
Yang J; Cao Q; Zhang H; Hao L; Zhou D; Gan Z; Li Z; Tong YX; Ji LN; Mao ZW
Biomaterials; 2018 Sep; 176():94-105. PubMed ID: 29870900
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of the pentose phosphate pathway by dichloroacetate unravels a missing link between aerobic glycolysis and cancer cell proliferation.
De Preter G; Neveu MA; Danhier P; Brisson L; Payen VL; Porporato PE; Jordan BF; Sonveaux P; Gallez B
Oncotarget; 2016 Jan; 7(3):2910-20. PubMed ID: 26543237
[TBL] [Abstract][Full Text] [Related]
20. Antitumor Therapy under Hypoxic Microenvironment by the Combination of 2-Methoxyestradiol and Sodium Dichloroacetate on Human Non-Small-Cell Lung Cancer.
Romero Y; Castillejos-López M; Romero-García S; Aguayo AS; Herrera I; Garcia-Martin MO; Torres-Espíndola LM; Negrete-García MC; Olvera AC; Huerta-Cruz JC; Cruz RV; Cisneros J; Soto EF; Solís-Chagoyán H; Mendoza-Milla C; Cabello-Gutiérrez C; Ruiz V; Aquino-Gálvez A
Oxid Med Cell Longev; 2020; 2020():3176375. PubMed ID: 33149807
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
