BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

267 related articles for article (PubMed ID: 31821048)

  • 1. Modulation of expression/function of intestinal P-glycoprotein under disease states.
    Murakami T; Bodor E; Bodor N
    Expert Opin Drug Metab Toxicol; 2020 Jan; 16(1):59-78. PubMed ID: 31821048
    [No Abstract]   [Full Text] [Related]  

  • 2. Factors and dosage formulations affecting the solubility and bioavailability of P-glycoprotein substrate drugs.
    Murakami T; Bodor E; Bodor N
    Expert Opin Drug Metab Toxicol; 2021 May; 17(5):555-580. PubMed ID: 33703995
    [No Abstract]   [Full Text] [Related]  

  • 3. Evaluation of the Role of P-glycoprotein (P-gp)-Mediated Efflux in the Intestinal Absorption of Common Substrates with Elacridar, a P-gp Inhibitor, in Rats.
    Suzuki K; Taniyama K; Aoyama T; Watanabe Y
    Eur J Drug Metab Pharmacokinet; 2020 Jun; 45(3):385-392. PubMed ID: 32078103
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Predicting drug-drug interactions involving the inhibition of intestinal CYP3A4 and P-glycoprotein.
    Tachibana T; Kato M; Takano J; Sugiyama Y
    Curr Drug Metab; 2010 Nov; 11(9):762-77. PubMed ID: 21189139
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Intestinal transporters: enhanced absorption through P-glycoprotein-related drug interactions.
    Zakeri-Milani P; Valizadeh H
    Expert Opin Drug Metab Toxicol; 2014 Jun; 10(6):859-71. PubMed ID: 24708201
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Quantitative evaluation of the function of small intestinal P-glycoprotein: comparative studies between in situ and in vitro.
    Adachi Y; Suzuki H; Sugiyama Y
    Pharm Res; 2003 Aug; 20(8):1163-9. PubMed ID: 12948013
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Strategies to overcome simultaneous P-glycoprotein mediated efflux and CYP3A4 mediated metabolism of drugs.
    Patel J; Mitra AK
    Pharmacogenomics; 2001 Nov; 2(4):401-15. PubMed ID: 11722289
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interplay of metabolism and transport in determining oral drug absorption and gut wall metabolism: a simulation assessment using the "Advanced Dissolution, Absorption, Metabolism (ADAM)" model.
    Darwich AS; Neuhoff S; Jamei M; Rostami-Hodjegan A
    Curr Drug Metab; 2010 Nov; 11(9):716-29. PubMed ID: 21189140
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prediction of Atorvastatin Pharmacokinetics in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats Using a Semiphysiologically Based Pharmacokinetic Model Involving Both Enzymes and Transporters.
    Wang Z; Yang H; Xu J; Zhao K; Chen Y; Liang L; Li P; Chen N; Geng D; Zhang X; Liu X; Liu L
    Drug Metab Dispos; 2019 Oct; 47(10):1066-1079. PubMed ID: 31399507
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of variations in the amounts of P-glycoprotein (ABCB1), BCRP (ABCG2) and CYP3A4 along the human small intestine on PBPK models for predicting intestinal first pass.
    Bruyère A; Declèves X; Bouzom F; Ball K; Marques C; Treton X; Pocard M; Valleur P; Bouhnik Y; Panis Y; Scherrmann JM; Mouly S
    Mol Pharm; 2010 Oct; 7(5):1596-607. PubMed ID: 20604570
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The pharmacological role of P-glycoprotein in the intestinal epithelium.
    Van Asperen J; Van Tellingen O; Beijnen JH
    Pharmacol Res; 1998 Jun; 37(6):429-35. PubMed ID: 9695116
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanistic analysis for drug permeation through intestinal membrane.
    Hayashi M; Tomita M
    Drug Metab Pharmacokinet; 2007 Apr; 22(2):67-77. PubMed ID: 17495413
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Baicalin reduces ciclosporin bioavailability by inducing intestinal p-glycoprotein in rats.
    Tian X; Chang Y; Wei J; Liu R; Wang L; Zhang J; Zhang X
    J Pharm Pharmacol; 2019 May; 71(5):788-796. PubMed ID: 30663770
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Crohn's Disease Is Associated with Decreased CYP3A4 and P-Glycoprotein Protein Expression.
    Wilson A; Urquhart BL; Ponich T; Chande N; Gregor JC; Beaton M; Kim RB
    Mol Pharm; 2019 Sep; 16(9):4059-4064. PubMed ID: 31393129
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium.
    Troutman MD; Thakker DR
    Pharm Res; 2003 Aug; 20(8):1210-24. PubMed ID: 12948019
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Impact of inflammation on the duodenal mRNA expression of CYP3A and P-glycoprotein in children with Crohn's disease.
    Fakhoury M; Lecordier J; Medard Y; Peuchmaur M; Jacqz-Agrain E
    Inflamm Bowel Dis; 2006 Aug; 12(8):745-9. PubMed ID: 16917230
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Intestinal efflux transporters and drug absorption.
    Murakami T; Takano M
    Expert Opin Drug Metab Toxicol; 2008 Jul; 4(7):923-39. PubMed ID: 18624680
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional alterations of intestinal P-glycoprotein under diabetic conditions.
    Kobori T; Harada S; Nakamoto K; Tokuyama S
    Biol Pharm Bull; 2013; 36(9):1381-90. PubMed ID: 23995645
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The gut as a barrier to drug absorption: combined role of cytochrome P450 3A and P-glycoprotein.
    Zhang Y; Benet LZ
    Clin Pharmacokinet; 2001; 40(3):159-68. PubMed ID: 11327196
    [TBL] [Abstract][Full Text] [Related]  

  • 20. P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel.
    Hendrikx JJ; Lagas JS; Rosing H; Schellens JH; Beijnen JH; Schinkel AH
    Int J Cancer; 2013 May; 132(10):2439-47. PubMed ID: 23090875
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.