BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

404 related articles for article (PubMed ID: 31822694)

  • 1. Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27.
    García-Gutiérrez L; Bretones G; Molina E; Arechaga I; Symonds C; Acosta JC; Blanco R; Fernández A; Alonso L; Sicinski P; Barbacid M; Santamaría D; León J
    Sci Rep; 2019 Dec; 9(1):18693. PubMed ID: 31822694
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins.
    Sangfelt O; Erickson S; Castro J; Heiden T; Gustafsson A; Einhorn S; Grandér D
    Oncogene; 1999 May; 18(18):2798-810. PubMed ID: 10362250
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Adhesion-regulated G1 cell cycle arrest in epithelial cells requires the downregulation of c-Myc.
    Benaud CM; Dickson RB
    Oncogene; 2001 Jul; 20(33):4554-67. PubMed ID: 11494151
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting cyclin-dependent kinase 1 (CDK1) but not CDK4/6 or CDK2 is selectively lethal to MYC-dependent human breast cancer cells.
    Kang J; Sergio CM; Sutherland RL; Musgrove EA
    BMC Cancer; 2014 Jan; 14():32. PubMed ID: 24444383
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Growth arrest by the cyclin-dependent kinase inhibitor p27Kip1 is abrogated by c-Myc.
    Vlach J; Hennecke S; Alevizopoulos K; Conti D; Amati B
    EMBO J; 1996 Dec; 15(23):6595-604. PubMed ID: 8978686
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation.
    Montagnoli A; Fiore F; Eytan E; Carrano AC; Draetta GF; Hershko A; Pagano M
    Genes Dev; 1999 May; 13(9):1181-9. PubMed ID: 10323868
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BCL-x(L) and BCL2 delay Myc-induced cell cycle entry through elevation of p27 and inhibition of G1 cyclin-dependent kinases.
    Greider C; Chattopadhyay A; Parkhurst C; Yang E
    Oncogene; 2002 Nov; 21(51):7765-75. PubMed ID: 12420213
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of murine gammaherpesvirus 68 v-cyclin interactions with cellular cdks.
    Upton JW; van Dyk LF; Speck SH
    Virology; 2005 Oct; 341(2):271-83. PubMed ID: 16102793
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Investigation of the cell cycle regulation of cdk3-associated kinase activity and the role of cdk3 in proliferation and transformation.
    Braun K; Hölzl G; Soucek T; Geisen C; Möröy T; Hengstschläger M
    Oncogene; 1998 Oct; 17(17):2259-69. PubMed ID: 9811456
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1).
    Perez-Roger I; Kim SH; Griffiths B; Sewing A; Land H
    EMBO J; 1999 Oct; 18(19):5310-20. PubMed ID: 10508164
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cyclin A but not cyclin D1 is essential for c-myc-modulated cell-cycle progression.
    Qi Y; Tu Y; Yang D; Chen Q; Xiao J; Chen Y; Fu J; Xiao X; Zhou Z
    J Cell Physiol; 2007 Jan; 210(1):63-71. PubMed ID: 17013808
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transforming growth factor beta(1) selectively inhibits the cyclic AMP-dependent proliferation of primary thyroid epithelial cells by preventing the association of cyclin D3-cdk4 with nuclear p27(kip1).
    Depoortere F; Pirson I; Bartek J; Dumont JE; Roger PP
    Mol Biol Cell; 2000 Mar; 11(3):1061-76. PubMed ID: 10712520
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression.
    O'Hagan RC; Ohh M; David G; de Alboran IM; Alt FW; Kaelin WG; DePinho RA
    Genes Dev; 2000 Sep; 14(17):2185-91. PubMed ID: 10970882
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Induction of apoptosis in human leukemia cells by the CDK1 inhibitor CGP74514A.
    Dai Y; Dent P; Grant S
    Cell Cycle; 2002; 1(2):143-52. PubMed ID: 12429924
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Baicalein induces a dual growth arrest by modulating multiple cell cycle regulatory molecules.
    Hsu SL; Hsieh YC; Hsieh WC; Chou CJ
    Eur J Pharmacol; 2001 Aug; 425(3):165-71. PubMed ID: 11513834
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Induction of G1 phase arrest in MCF human breast cancer cells by pentagalloylglucose through the down-regulation of CDK4 and CDK2 activities and up-regulation of the CDK inhibitors p27(Kip) and p21(Cip).
    Chen WJ; Chang CY; Lin JK
    Biochem Pharmacol; 2003 Jun; 65(11):1777-85. PubMed ID: 12781329
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of structurally related flavonoids on cell cycle progression of human melanoma cells: regulation of cyclin-dependent kinases CDK2 and CDK1.
    Casagrande F; Darbon JM
    Biochem Pharmacol; 2001 May; 61(10):1205-15. PubMed ID: 11322924
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A new pathway for mitogen-dependent cdk2 regulation uncovered in p27(Kip1)-deficient cells.
    Coats S; Whyte P; Fero ML; Lacy S; Chung G; Randel E; Firpo E; Roberts JM
    Curr Biol; 1999 Feb; 9(4):163-73. PubMed ID: 10074425
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Retinoic acid-mediated G1 arrest is associated with induction of p27(Kip1) and inhibition of cyclin-dependent kinase 3 in human lung squamous carcinoma CH27 cells.
    Hsu SL; Hsu JW; Liu MC; Chen LY; Chang CD
    Exp Cell Res; 2000 Aug; 258(2):322-31. PubMed ID: 10896783
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cyclins and CDKS in development and cancer: lessons from genetically modified mice.
    Santamaria D; Ortega S
    Front Biosci; 2006 Jan; 11():1164-88. PubMed ID: 16146805
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.