BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

484 related articles for article (PubMed ID: 31825716)

  • 1. The extent of Ssa1/Ssa2 Hsp70 chaperone involvement in nuclear protein quality control degradation varies with the substrate.
    Jones RD; Enam C; Ibarra R; Borror HR; Mostoller KE; Fredrickson EK; Lin J; Chuang E; March Z; Shorter J; Ravid T; Kleiger G; Gardner RG
    Mol Biol Cell; 2020 Feb; 31(3):221-233. PubMed ID: 31825716
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Degradation Signals for Ubiquitin-Proteasome Dependent Cytosolic Protein Quality Control (CytoQC) in Yeast.
    Maurer MJ; Spear ED; Yu AT; Lee EJ; Shahzad S; Michaelis S
    G3 (Bethesda); 2016 Jul; 6(7):1853-66. PubMed ID: 27172186
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ubiquitin conjugation triggers misfolded protein sequestration into quality control foci when Hsp70 chaperone levels are limiting.
    Shiber A; Breuer W; Brandeis M; Ravid T
    Mol Biol Cell; 2013 Jul; 24(13):2076-87. PubMed ID: 23637465
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hsp70 targets a cytoplasmic quality control substrate to the San1p ubiquitin ligase.
    Guerriero CJ; Weiberth KF; Brodsky JL
    J Biol Chem; 2013 Jun; 288(25):18506-20. PubMed ID: 23653356
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Type II Hsp40 Sis1 cooperates with Hsp70 and the E3 ligase Ubr1 to promote degradation of terminally misfolded cytosolic protein.
    Summers DW; Wolfe KJ; Ren HY; Cyr DM
    PLoS One; 2013; 8(1):e52099. PubMed ID: 23341891
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Direct involvement of Hsp70 ATP hydrolysis in Ubr1-dependent quality control.
    Singh A; Vashistha N; Heck J; Tang X; Wipf P; Brodsky JL; Hampton RY
    Mol Biol Cell; 2020 Nov; 31(24):2669-2686. PubMed ID: 32966159
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Distinct proteostasis circuits cooperate in nuclear and cytoplasmic protein quality control.
    Samant RS; Livingston CM; Sontag EM; Frydman J
    Nature; 2018 Nov; 563(7731):407-411. PubMed ID: 30429547
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hsp70-Hsp110 chaperones deliver ubiquitin-dependent and -independent substrates to the 26S proteasome for proteolysis in yeast.
    Kandasamy G; Andréasson C
    J Cell Sci; 2018 Mar; 131(6):. PubMed ID: 29507114
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Exposed hydrophobicity is a key determinant of nuclear quality control degradation.
    Fredrickson EK; Rosenbaum JC; Locke MN; Milac TI; Gardner RG
    Mol Biol Cell; 2011 Jul; 22(13):2384-95. PubMed ID: 21551067
    [TBL] [Abstract][Full Text] [Related]  

  • 10. N-Myristoylation of the Rpt2 subunit of the yeast 26S proteasome is implicated in the subcellular compartment-specific protein quality control system.
    Kimura A; Kurata Y; Nakabayashi J; Kagawa H; Hirano H
    J Proteomics; 2016 Jan; 130():33-41. PubMed ID: 26344132
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The San1 Ubiquitin Ligase Functions Preferentially with Ubiquitin-conjugating Enzyme Ubc1 during Protein Quality Control.
    Ibarra R; Sandoval D; Fredrickson EK; Gardner RG; Kleiger G
    J Biol Chem; 2016 Sep; 291(36):18778-90. PubMed ID: 27405755
    [TBL] [Abstract][Full Text] [Related]  

  • 12. How a disordered ubiquitin ligase maintains order in nuclear protein homeostasis.
    Rosenbaum JC; Gardner RG
    Nucleus; 2011; 2(4):264-70. PubMed ID: 21941105
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular mass as a determinant for nuclear San1-dependent targeting of misfolded cytosolic proteins to proteasomal degradation.
    Amm I; Wolf DH
    FEBS Lett; 2016 Jun; 590(12):1765-75. PubMed ID: 27173001
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular chaperones of the Hsp70 family assist in the assembly of 20S proteasomes.
    Hammack LJ; Firestone K; Chang W; Kusmierczyk AR
    Biochem Biophys Res Commun; 2017 Apr; 486(2):438-443. PubMed ID: 28322792
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Previously unknown role for the ubiquitin ligase Ubr1 in endoplasmic reticulum-associated protein degradation.
    Stolz A; Besser S; Hottmann H; Wolf DH
    Proc Natl Acad Sci U S A; 2013 Sep; 110(38):15271-6. PubMed ID: 23988329
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The stress response against denatured proteins in the deletion of cytosolic chaperones SSA1/2 is different from heat-shock response in Saccharomyces cerevisiae.
    Matsumoto R; Akama K; Rakwal R; Iwahashi H
    BMC Genomics; 2005 Oct; 6():141. PubMed ID: 16209719
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HSP70-binding motifs function as protein quality control degrons.
    Abildgaard AB; Voutsinos V; Petersen SD; Larsen FB; Kampmeyer C; Johansson KE; Stein A; Ravid T; Andréasson C; Jensen MK; Lindorff-Larsen K; Hartmann-Petersen R
    Cell Mol Life Sci; 2023 Jan; 80(1):32. PubMed ID: 36609589
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The cytoplasmic Hsp70 chaperone machinery subjects misfolded and endoplasmic reticulum import-incompetent proteins to degradation via the ubiquitin-proteasome system.
    Park SH; Bolender N; Eisele F; Kostova Z; Takeuchi J; Coffino P; Wolf DH
    Mol Biol Cell; 2007 Jan; 18(1):153-65. PubMed ID: 17065559
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hsp70 nucleotide exchange factor Fes1 is essential for ubiquitin-dependent degradation of misfolded cytosolic proteins.
    Gowda NK; Kandasamy G; Froehlich MS; Dohmen RJ; Andréasson C
    Proc Natl Acad Sci U S A; 2013 Apr; 110(15):5975-80. PubMed ID: 23530227
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein.
    Huyer G; Piluek WF; Fansler Z; Kreft SG; Hochstrasser M; Brodsky JL; Michaelis S
    J Biol Chem; 2004 Sep; 279(37):38369-78. PubMed ID: 15252059
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.